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Baocun Zhao,Fenglian Liu,Guiyan Li,Rongjie Xu,Jing Yang 대한금속·재료학회 2013 METALS AND MATERIALS International Vol.19 No.3
Multi-axis deformation (MAD) tests were performed on a low carbon microalloyed steel with different process parameters. The effect of temperature and strain on the microstructure evolution were analyzed. The strain reversal effect was observed from the comparison between the microstructure resulting from the MAD process and the one from a uniaxial deformation process. However, with 0.3 strain per pass and the alternating compression time equal to 10 or more during the MAD process, ultra fine structures were obtained at deformation temperature below 800 °C. Due to the microalloyed elements in the tested steel, nanometer sized precipitates were introduced under MAD conditions, which also contributed to the microstructure refinement.
Zhao, ZhengLin,Kim, Sang Chan,Wu, YiYan,Zhang, Jie,Xu, YanJi,Cho, Il Je,Yang, Chae Ha,Lee, Bong Hyo,Zhao, RongJie Elsevier 2014 Neuroscience Letters Vol.567 No.-
The role of neuropeptide Y (NPY) in the central nucleus of amygdala (CeA) in the preventive effects of acupuncture against ethanol withdrawal-induced anxiety was investigated. Rats were treated with 3 g/kg/day of ethanol for 28 days, followed by 3 days of withdrawal. Bilateral acupuncture treatment at HT7 (Shen-Men), PC6 (Nei-Guan) or a non-acupoint was respectively added to the rats during the withdrawal once a day for three days. Enzyme-linked immunosorbent assays and real-time polymerase chain reaction analyses showed there was a significant decrease in NPY protein and mRNA expression in the CeA during ethanol withdrawal, which was reversed by acupuncture at HT7 but neither at PC6 nor at a non-acupoint. Acupuncture at HT7 also greatly inhibited the decrease in cAMP response element-binding protein (CREB) phosphorylation in the CeA. In elevated plus maze tests, a selective NPY Y1 receptor antagonist BIBP 3226 into the CeA before the acupuncture abolished almost completely the anxiolytic effect of acupuncture at HT7. These results suggest that acupuncture at HT7 rescues the depletion of amygdaloid NPY and reverses the decrease in CREB phosphorylation to produce anxiolytic effects during ethanol withdrawal. (C) 2014 Elsevier Ireland Ltd. All rights reserved.