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      저자 : Richard Wix-Ramos (검색결과 1 건)
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        Drug Treated Schizophrenia, Schizoaffective and Bipolar Disorder Patients Evaluated by qEEG Absolute Spectral Power and Mean Frequency Analysis

        Richard Wix-Ramos,Antonio Eblen-Zajjur,Xiomara Moreno,Eduardo Capote,Gilbert González,Ezequiel Uribe 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.1

        Objective: Research of electroencephalograph (EEG) power spectrum and mean frequency has shown inconsistent results inpatients with schizophrenic, schizoaffective and bipolar disorders during medication when compared to normal subjects thus;the characterization of these parameters is an important task. Methods: We applied quantitative EEG (qEEG) to investigate 38 control, 15 schizophrenic, 7 schizoaffective and 11 bipolar disordersubjects which remained under the administration of psychotropic drugs (except control group). Absolute spectral power (ASP),mean frequency and hemispheric electrical asymmetry were measured by 19 derivation qEEG. Group mean values were comparedwith non parametrical Mann-Whithney test and spectral EEG maps with z-score method at p<0.05. Results: Most frequent drug treatments for schizophrenic patients were neuroleptic+antiepileptic (40% of cases) or 2 neuroleptics(33.3%). Schizoaffective patients received neuroleptic+benzodiazepine (71.4%) and for bipolar disorder patients neuroleptic+antiepileptic (81.8%). Schizophrenic (at all derivations except for Fp1, Fp2, F8 and T6) and schizoaffective (only at C3)show higher values of ASP (+57.7% and +86.1% respectively) compared to control group. ASP of bipolar disorder patients didnot show differences against control group. The mean frequency was higher at Fp1 (+14.2%) and Fp2 (+17.4%) in bipolar disorderpatients than control group, but no differences were found in frequencies between schizophrenic or schizoaffective patientsagainst the control group. Majority of spectral differences were found at the left hemisphere in schizophrenic and schizoaffectivebut not in bipolar disorder subjects. Conclusion: The present report contributes to characterize quantitatively the qEEG in drug treated schizophrenic, schizoaffectiveor bipolar disorder patients.

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