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- 저자 : Rasoulian, Javid (검색결과 3 건)
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Alijani Babak,Rasoulian Javid 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.3
Study Design: This was a prospective clinical study.Purpose: Previous studies have indicated that cervical lordosis is a parameter influenced by segmental and global spinal sagittal balance parameters. However, this correlation still remains unclear. Therefore, a better understanding of the normal values and interdependencies between inter-segmental alignment parameters is needed. This is a preliminary analysis that helps to understand these factors.Overview of Literature: Change in global sagittal alignment is associated with poor health-related quality of life. Questions regarding which parameters play the primary roles in the progression of spinal sagittal imbalance and which might be compensatory factors remain unanswered.Methods: Prospectively, 420 adults (105 asymptomatic, 105 cervical symptomatic, 105 lumbar symptomatic, and 105 post-surgical) were selected. Whole-spine standing lateral radiographs were taken, and spinopelvic, thoracic, and cervical parameters were measured. Then, the data were analyzed using correlation coefficient test and multiple regression analysis.Results: All the parameters showed a normal distribution. The mean values of the cervical parameters are as follows: C<sub>1</sub>C<sub>2</sub> Cobb angle, −27.07°±4.3°; C<sub>2</sub>C<sub>7</sub> Cobb angle, −16.4°±5.6°; O<sub>C</sub>C<sub>2</sub> Cobb angle, −14.5°±3.8°; O<sub>C</sub>C<sub>7</sub> Cobb angle, −29.8°±5.6°; C<sub>2</sub>C<sub>7</sub> Harrison angle, 20.4°±4.3°; and C<sub>7</sub> slope, −25.4°±5.6°. The analysis of these parameters revealed no statistically significant difference between asymptomatic, symptomatic, and post-surgical patients. C<sub>7</sub> sagittal vertical axis (SVA) correlated with the C<sub>2</sub>C<sub>7</sub> Cobb angle (<i>r</i> =0.7) in all groups. No significant correlation was noted between cervical and spinopelvic parameters in asymptomatic patients. However, C<sub>1</sub>C<sub>2</sub> Cobb angle correlated significantly with pelvic incidence (PI, <i>r</i> =−0.2), lumbar lordosis (LL, <i>r</i> =0.2), and pelvic tilt (PT, <i>r</i> =−0.2) in cervical symptomatic patients. Irrespective of the patient symptom sub-group (n=420), C<sub>1</sub>C<sub>2</sub> Cobb angle correlated with LL (<i>r</i> =0.1) and C<sub>2</sub>C<sub>7</sub> Harrison angle correlated with PI and PT (<i>r</i> =0.1).Conclusions: Our results indicate significant interdependence between the spinopelvic and cervical alignment, especially in cervical symptomatic patients. In addition, strong correlation was found between the C<sub>7</sub> SVA and C<sub>2</sub>C<sub>7</sub> Cobb angle. Overall, the results of this study could help to better understand the cervical sagittal alignment and serve as preliminary data for planning surgical reconstruction procedures.
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Reza Sepahvand,Saeed Esmaeili-Mahani,Ardeshir Arzi,Bahram Rasoulian,Mehdi Abbasnejad 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.6
Ginger (Zingiber officinale Roscoe), a well-known spice plant, has been used traditionally in the treatment of a wide variety of ailments. It has been shown that ginger is a calcium channel blocker; however, its influence on morphine analgesic effects has not been elucidated. We examined the effect of ginger root extract on nociceptive threshold and morphine-induced analgesia in male Wistar rats. To determine the effect of ginger on morphine analgesia, ginger extract (200, 400, and 600mg/kg i.p.) was injected before a subeffective dose of morphine (2.5mg/kg i.p.). The radiant heat tail-flick test was used to assess the nociceptive threshold before and at different times after drug administration. Our results showed that ginger extract elicited a significant antinociceptive effect. In addition, in groups that received both morphine and ginger, the observed analgesia was higher than that in groups treated with either morphine or ginger extract alone. Thus, the data indicate that ginger extract has a beneficial influence on morphine analgesia and can be an efficacious adjunct for pain management.
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Knowledge about Colorectal Cancer in Northern Iran: a Population-Based Telephone Survey
Mansour-Ghanaei, Alireza,Joukar, Farahnaz,Mansour-Ghanaei, Fariborz,Rasoulian, Javid,Naghipour, Mohammad Reza,Fani, Arezoo,Kazemnejad, Ehsan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17
Background: Colorectal cancer (CRC) is one of the most common malignancies of the gastrointestinal tract. The aim of this study was to assess the general knowledge of CRC in individuals living in Rasht, Iran, using a population-based cross-sectional telephone survey. Materials and Methods: A total of 1557 participants between 18 and 80 years of age were interviewed using random sampling from the telephone directory. Knowledge of risk factors, symptoms, diagnosis, and prevention of CRC was assessed using a validated questionnaire. Results: The mean knowledge level of the 1,557 respondents (average age 46 y) was $13.5{\pm}4.29$ (maximum possible score = 26), and 46.4% (722/1,557) of the subjects achieved grades lower than the mean score. The mean scores for knowledge of symptoms and risk factors were $3.97{\pm}1.83$ (range: 0-7) and $5.17{\pm}1.65$ (range: 0-9), respectively. Older age, higher education, and employment were significantly associated with better scores for recognition of risk factors and warning symptoms. The majority of subjects correctly identified weight loss (70.2%; 1,093/1,557) and rectal bleeding (63.3%; 986/1,557) as symptoms of CRC, and that smoking (85.9%; 1,337/1,557) and a low-fiber diet (73.4%; 1,143/1,557) were risk factors. Approximately half of the subjects noted increasing age, genetic background and fried food as other risk factors. A considerable number (54.8%; 853/1,557) identified colonoscopy as a screening method for detecting CRC in asymptomatic patients. However, a third of the subjects in the target group for screening (${\geq}50y$) were not interested in undergoing screening, primarily due to a lack of symptoms. Conclusions: Our results suggest that the knowledge of CRC is poor among the public, and therefore greater attempts should be made to increase awareness. Public education emphasizing the risk factors and symptoms of CRC, as well as the importance of regular screening regardless of the presence of symptoms, may help to reduce CRC morbidity and mortality.
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