Numerical simulation on mining effect influenced by a normal fault and its induced effect on rock burst

Jiang, Jin-Quan,Wang, Pu,Jiang, Li-Shuai,Zheng, Peng-Qiang,Feng, Fan Techno-Press 2018 Geomechanics & engineering Vol.14 No.4

The study of the mining effect influenced by a normal fault has great significance concerning the prediction and prevention of fault rock burst. According to the occurrence condition of a normal fault, the stress evolution of the working face and fault plane, the movement characteristics of overlying strata, and the law of fault slipping when the working face advances from footwall to hanging wall are studied utilizing UDEC numerical simulation. Then the inducing-mechanism of fault rock burst is revealed. Results show that in pre-mining, the in situ stress distribution of two fault walls in the fault-affected zone is notably different. When the working face mines in the footwall, the abutment stress distributes in a "double peak" pattern. The ratio of shear stress to normal stress and the fault slipping have the obvious spatial and temporal characteristics because they vary gradually from the higher layer to the lower one orderly. The variation of roof subsidence is in S-shape which includes slow deformation, violent slipping, deformation induced by the hanging wall strata rotation, and movement stability. The simulation results are verified via several engineering cases of fault rock burst. Moreover, it can provide a reference for prevention and control of rock burst in a fault-affected zone under similar conditions.

A simple approach to the elasto-plastic coupling analyses of circular tunnels in confining pressure-dependent strain-softening rock masses

Qiang Zhang,Cheng Li,Qiang Guo,Ming Min,Yanning Wang,Binsong Jiang 한국자원공학회 2017 Geosystem engineering Vol.20 No.5

The conventional strain-softening behaviors which assume the strength parameters as the functions of the plastic strain have been studied using various methods. However, rock-like materials have also been found to manifest pressure-dependent behavior for both elastic and plastic rock masses. The realization of the radial stress was found to be continuous, and gradually increased from supporting stress to in situ stress for the circular openings under hydrostatic pressure. The radial stress was spaced as numbers of sections, and each annulus was considered as an ideal plastic rock mass. The close-formed analytical solutions of each annulus can be easily obtained. Therefore, using the displacement continuum and stress boundary conditions, the dimensionless radius corresponding to the spaced radius could be derived. The radial stress and plastic shear strain at the inner radius of the outer adjacent annulus were employed to describe the material property evolution law. Then, the radii could be recursively obtained. Finally, for the conventional strain-softening rock masses, the pressure-dependent elastic rock and elasto-plastic coupling strain-softening rock masses were employed to validate the proposed approach. In this study, having completed the above steps, it was concluded that the results were in accordance with the numerical methods.

Overexpression and Clinicopathological Contribution of DcR3 in Bladder Urothelial Carcinoma Tissues

Jiang, Yi-Qiang,Zhong, Teng-Fei,Dang, Yi-Wu,Zou, Ling-Song,Yang, Liu,Yang, Xia,Chen, Gang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21

Background: To explore the expression of DcR3 protein and its clinicopathological significance in bladder urothelial carcinomas (BUC). Materials and Methods: Immunohistochemistry was performed to detect the expression of DcR3, caspase-3, Bcl-2, VEGF, Ki-67, PCNA and P53 in 166 BUC and 56 normal bladder tissues. Western blotting was used to detect the expression of DcR3 in the supernatants of cultured BUC cells. Results: Overexpression of DcR3 was found in BUC tissues and cell lines, with significant elevation as compared to normal bladder tissues (p<0.0001). Higher DcR3 expression was related to the status of invasion, lymph node metastasis and recurrence. Furthermore, DcR3 expression was negatively correlated with caspase-3 and positively associated with Bcl-2, VEGF, Ki-67 labeling index (LI), PCNA LI and P53 (all p<0.0001), respectively. Conclusions: DcR3 may play a crucial role as an oncogene in tumorigenesis, deterioration and progress of BUC via influencing related pathways of apoptosis, proliferation and angiogenesis. The detection of DcR3 protein in the formalinfixed and paraffin-embedded samples could assist to predict in prognosis of BUC patients.

MicroRNA-214-mediated UBC9 expression in glioma

( Zhi Qiang Zhao ),( Xiao Chao Tan ),( Ani Zhao ),( Li Yuan Zhu ),( Bin Yin ),( Jiang Ang Yuan ),( Bo Qin Qiang ),( Xiao Zhong Peng ) 생화학분자생물학회(구 한국생화학분자생물학회) 2012 BMB Reports Vol.45 No.11

It has been reported that ubiquitin-conjugating enzyme 9 (Ubc9), the unique enzyme2 in the sumoylation pathway, is up-regulated in many cancers. However, the expression and regulation of UBC9 in glioma remains unknown. In this study, we found that Ubc9 was up-regulated in glioma tissues and cell lines compared to a normal control. UBC9 knockdown by small interfering RNA (siRNA) affected cell proliferation and apoptosis in T98G cells. Further experiments revealed that microRNA (miR)-214 directly targeted the 3` untranslated region (UTR) of UBC9 and that there was an inverse relationship between the expression levels of miR-214 and UBC9 protein in glioma tissues and cells. MiR-214 overexpression suppressed the endogenous UBC9 protein and affected T98G cell proliferation. These findings suggest that miR-214 reduction facilitates UBC9 expression and is involved in the regulation of glioma cell proliferation.

Partition of Nitrogen Between Microbial Biomass Nitrogen and Plant Nitrogen Uptake Influenced By Dicyandiamide, Hydroquinone and Carbon Addition

Qiang Ma,Hua Zhou,Chunming Jiang,Yonggang Xu,Wantai Yu 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Design of Course-Keeping Controller for a Ship Based on Backstepping and Neural Networks

Qiang ZHANG,Na JIANG,Yancai HU,Dewei PAN 국제이네비해양경제학회 2017 International Journal of e-Navigation and Maritime Vol.7 No.1

Due to the existence of uncertainties and the unknown time variant environmental disturbances for ship course nonlinear control system, the ship course adaptive neural network robust course-keeping controller is designed by combining the backstepping technique. The neural networks (NNs) are employed for the compensating of the nonlinear term of the nonlinear ship course-keeping control system. The designed adaptive laws are designed to estimate the weights of NNs and the bounds of unknown environmental disturbances. The first order commander are introduced to solve the problem of repeating differential operations in the traditional backstepping design method, which let the designed controller easier to implement in navigation practice and structure simplicity. Theoretically, it indicates that the proposed controller can track the setting course in arbitrary expected accuracy, while keeping all control signals in the ship course control closed-loop system are uniformly ultimately bounded. Finally, the training ship of Dalian Maritime University is taken for example; simulation results illustrated the effectiveness and the robustness of the proposed controller.

Thrust distribution of underwater salvage robot based on PSO optimization algorithm

Jiang Yu An,Guo Gao Yang,Zhang Qiang 국제이네비해양경제학회 2023 International Journal of e-Navigation and Maritime Vol.20 No.-

In order to solve the problem of improper thrust distribution of each thruster of underwater vehicle, the PSO optimization algorithm is used to solve the problem of thrust distribution. According to the spatial layout of the thruster, the algorithm model of the underwater vehicle propulsion system is established. The thrust input is carried out under the broken line search trajectory, and the simulation verifies the thrust allocation results of the PSO algorithm and the traditional pseudo-inverse method. The simulation results show that compared with the traditional algorithm. First of all, the PSO algorithm can set the physical threshold for each thruster to prevent the thruster from having too much thrust. Secondly, it can ensure that the thruster can turn with a reasonable torque to prevent the robot from drifting due to the large thrust gap. This paper provides a theoretical reference for thrust distribution of underwater salvage robot, and has practical engineering significance.

Effects of ultrasonic treatment on the gel properties of microbial transglutaminase crosslinked soy, whey and soy–whey proteins

Qiang Cui,Xibo Wang,Guorong Wang,Rui Li,Xiaodan Wang,Shuang Chen,Jingnan Liu,Lianzhou Jiang 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.5

This paper studied the influences of diverse ultrasonic power treatments on the physico-chemical properties of soy–whey mixed protein induced by microbial transglutaminase. Two groups of 15% (m/v) of protein solution-sole protein (as control group) and mixed protein were prepared and processed under different ultrasonic powers for 30 min. After ultrasonic power treatments, gel properties were significantly increased: under 300 W, the gel hardness of mixed protein reached a maximum of 998.9 g, with its water binding capacity scoring a maximum of 87%. According to the analysis of fluorescence emission spectrum, the fluorescence intensity and maximum absorption peak had changed, for different ultrasonic power treatments had exposed more groups. The Fourier Transform Infrared Spectroscopy also suggested that ultrasonic power treatments could change the secondary structure of gel samples. The scanning electron microscope demonstrated that the network structure of mixed protein gel displayed more regular and uniform after ultrasonic treatments.

Dihydroartemisinin inhibits HepG2.2.15 proliferation by inducing cellular senescence and autophagy

( Jiang Zou ),( Qiang Ma ),( Ru Sun ),( Jiajing Cai ),( Hebin Liao ),( Lei Xu ),( Jingruo Xia ),( Guangcheng Huang ),( Lihua Yao ),( Yan Cai ),( Xiaowu Zhong ),( Xiaolan Guo ) 생화학분자생물학회(구 한국생화학분자생물학회) 2019 BMB Reports Vol.52 No.8

Dihydroartemisinin (DHA) has been reported to possess anti-cancer activity against many cancers. However, the pharmacologic effect of DHA on HBV-positive hepatocellular carcinoma (HCC) remains unknown. Thus, the objective of the present study was to determine whether DHA could inhibit the proliferation of HepG2.2.15 cells and uncover the underlying mechanisms involved in the effect of DHA on HepG2.2.15 cells. We found that DHA effectively inhibited HepG2.2.15 HCC cell proliferation both in vivo and in vitro. DHA also reduced the migration and tumorigenicity capacity of HepG2.2.15 cells. Regarding the underlying mechanisms, results showed that DHA induced cellular senescence by up-regulating expression levels of proteins such as p-ATM, p-ATR, γ-H₂AX, P53, and P21 involved in DNA damage response. DHA also induced autophagy (green LC3 puncta gathered together and LC3II/LC3I ratio increased through AKT-mTOR pathway suppression). Results also revealed that DHA-induced autophagy was not linked to senescence or cell death. TPP1 (telomere shelterin) overexpression could not rescue DHA-induced anticancer activity (cell proliferation). Moreover, DHA down-regulated TPP1 expression. Gene knockdown of TPP1 caused similar phenotypes and mechanisms as DHA induced phenotypes and mechanisms in HepG2.2.15 cells. These results demonstrate that DHA might inhibit HepG2.2.15 cells proliferation through inducing cellular senescence and autophagy. [BMB Reports 2019; 52(8): 520-525]

Dynamic characteristics of the cavitation clouds of submerged Helmholtz self-sustained oscillation jets from high-speed photography

Qiang Wu,Wei Wei,Bo Deng,Pan Jiang,Deng Li,Mengda Zhang,Zhenlong Fang 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.2

Experiments were conducted to investigate the cavitation behavior of Helmholtz self-sustained oscillation jets. In this paper, highspeed photographic technology was used to capture the flow details of cavitation with various nozzle structures and operating pressures from 1.0 MPa to 3.0 MPa. Furthermore, an in-house code based on a matrix approach that processes gray values with various statistical methods was used to quantitatively evaluate the cavitation jet of waters generated by Helmholtz nozzles. The mean values of the normalized gray levels of the images were used as a metric to measure the lengths of the cavitation clouds. When the original data were smoothed by a 15th lowess filter to exclude the noise of the images, the periods of cavitation cloud shedding were obtained accordingly, and the average period had a magnitude of 10 -4 . All of the smoothed results of the original data captured a two-peak shape that comprises a large peak and a mild hump. Image processing results showed that the Helmholtz nozzle produced greater cavitation intensity than a traditional conical nozzle. The shear-layer instability waves disappeared within 10d 1 downstream from the injector exit. The cavitation clouds propagated a distance of approximately 1–10d 1 at various pressure ratios, and the clouds were continuous within this distance. The geometry of the nozzle strongly affected the length and shedding period of the cavitation cloud. As described in the discussion section of this paper, when the cavity length was doubled, the length of the cavitation cloud decreased approximately 26.5 %; however, the period of the cavitation cloud shedding increased approximately 10 %. The longest cavitation cloud appeared when the ratio of the cavity diameter and the upper nozzle diameter was eight. Excessively small or large diameters were not conducive to the development of cavitation, whereas the effect of the pressure ratio on the cavitation cloud length was positive. When other conditions remained unchanged, the lump shedding period decreased as the pressure ratio was increased to 25. When the pressure ratio exceeded 25, the cavitation cloud shedding period remained constant.