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- 저자 : Pawan Kumar Verma (검색결과 3 건)
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Nitin Kumar,Pawan Kumar Verma,Vinod Kumar 대한전자공학회 2022 IEIE Transactions on Smart Processing & Computing Vol.11 No.1
This paper presents energy-efficient clustering protocols for three-tier heterogeneous wireless sensor networks (WSNs) along with their applications to the systems. The performance of a new dynamic, modified, probability-based approach to finding the most energy-efficient cluster head nodes is intended to extend network lifetime. Mathematical modeling and simulation results from using MATLAB-2017b provide a comparative analysis of several heterogeneous and homogeneous WSN variants in terms of energy consumption, active versus dead nodes, and network lifetime based on first node dead (FND) and last node dead (LND). ADV-LEACH2 in a three-tier heterogeneous network performs better than homogeneous and two-tier heterogeneous networks owing to super nodes with higher energy levels.
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Gaurav Gupta,Ajay Shahbaj,Dharmendra Kumar Pipal,Pawan Saini,Vijay Verma,Sangeeta Gupt,Vibha Rani,Seema Yadav 대한내시경로봇외과학회 2022 Journal of Minimally Invasive Surgery Vol.25 No.4
Purpose: Uncertainty exists about whether early laparoscopic cholecystectomy (LC) is an appropriate surgical treatment for acute calculous cholecystitis. This study aimed to compare early vs. late LC for acute calculous cholecystitis regarding intraoperative difficulty and postoperative outcomes. Methods: This was a prospective randomized study carried out between December 2015 and June 2017; 60 patients with acute calculous cholecystitis were divided into two groups (early and delayed groups), each comprising 30 patients. Thirty patients treated with LC within 3 to 5 days of arrival at the hospital were assigned to the early group. The other 30 patients were placed in the delayed group, first treated conservatively, and followed by LC 3 to 6 weeks later. Results: The conversion rates in both groups were 6.7% and 0%, respectively (p = 0.143). The operating time was 56.67 ± 11.70 minutes in the early group and 75.67 ± 20.52 minutes in the delayed group (p = 0.001), and both groups observed equal levels of postoperative complications. Early LC patients, on the other hand, required much fewer postoperative hospital stay (3.40 ± 1.99 vs. 6.27 ± 2.90 days, p = 0.006). Conclusion: Considering shorter operative time and hospital stay without significant increase of open conversion rates, early LC might have benefits over late LC.
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Naseem, Sania,Sultana, Mudasir,Raina, Rajinder,Pankaj, Nrip Kishore,Verma, Pawan Kumar,Nasir, Nasir Ahmad,Ahanger, Azad Ahmad,Rahman, Shafiqur,Prawez, Shahid The Korean Society of Veterinary Science 2011 大韓獸醫學會誌 Vol.51 No.4
Amikacin is a semisynthetic derivative of kanamycin and primarily active against aerobic Gram-negative-pathogens with limited activity against Gram-positive bacteria. Meager study was reported on pharmacokinetic data on multi-days administration of amikacin. Hence, pharmacokinetics study was done in five clinically healthy goats (n = 5), after intravenous bolus injection of amikacin sulfate at the dose rate of 10 mg/kg body weight daily for three consecutive days. The amikacin concentrations in plasma and pharmacokinetics-parameters were analyzed by using microbiological assay technique and noncompartmental open-model, respectively. The mean peak plasma concentrations (Mean ${\pm}$ SD) of amikacin at time zero ($Cp^{0}$) was $114.19{\pm}20.78$ and $128.67{\pm}14.37{\mu}g/mL$, on day 1st and 3rd, respectively. The mean elimination half-life ($t_{1/2}ke$) was $1.00{\pm}0.28h$ on day 1st and $1.22{\pm}0.29h$ on day 3rd. Mean of area under concentration-time curve ($AUC_{0{\rightarrow}{\infty}}$) was $158.26{\pm}60.10$ and $159.70{\pm}22.74{\mu}g.h/mL$, on day 1st and 3rd respectively. The total body clearance ($Cl_{B}$) and volume of distribution at steady state (Vdss) on day 1st and 3rd were $Cl_{B}=0.07{\pm}0.02$ and $0.06{\pm}0.01L/h.kg$ and $Vdss=0.10{\pm}0.03$ and $0.11{\pm}0.05L/kg$, respectively. No-significant difference was noted in both drug-plasma concentration and pharmacokinetics-parameters, respectively. Amikacin concentration in plasma was found higher up-to 4 h and 6 h onward on down-ward trends favour to reduce toxicity. Which also support the pharmacokinetic-pharmacodynamic way of dosing of aminoglycosides and hence, amikacin may be administered 10 mg/kg intravenously daily to treat principally Gram-negative pathogens and limitedly Gram-positive-pathogens.
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