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- 저자 : Oh Sumin (검색결과 104 건)
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( Sumin Oh ),( Hyun Hoon Chung ),( Jae Weon Kim ),( Yong Sang Song ),( Noh Hyun Park ),( Yoo Kyung Lee ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
Objective: Despite the good prognosis of borderline ovarian tumors (BOTs), a few BOT patients experience the relapse of disease. Among them, some reveal the cancerous disease, however, the risk of malignant transformation of BOT is usually thought to be unclear. We intended to find out the specific characteristics and prognosis of cancerous recurrence from BOTs. Methods: Between 1995 and 2012, 130 women were diagnosed with BOTs in our institution. Seven patients diagnosed and treated for cancerous recurrence of BOTs were included for analysis in this retrospective study. Clinicopathological characteristics and surgical procedure as well as follow-up data with overall survival were assessed. Statistical analyses included the χ2 test, t-test and Log-rank test with Cox regression. Result: One hundred and thirty patients with mean follow-up of 65.8 months (range, 1 to 241 months) were evaluated, of whom half were below 40 years-old at their first diagnosis of BOTs and 53.8% received conservative surgery. In our cohort, mucinous pathologic type was the most common one (66.9%). Among 11 patients who were diagnosed relapse of BOTs (8.5%), seven cancerous transformations were detected (5.4%) with median time of 9 months (range, 1 to 54 months). All cancerous relapses arose from premenopausal women of median age of 35 years old. Tumor size and tumor markers level (CA-125 and CA 19-9) did not show any predictive value for the malignant transformation of BOTs. Laparoscopic approach and conservative surgery were revealed that had no significant influence on relapse and overall survival (p=0.602, p=0.543). The median survival time of cancerous recurrent cases is 9 months (range, 3 to 31 months). Among them, four died of recurrent disease (ovarian cancer) and the other 3 has been reached complete remission. Conclusion: Minimal invasive conservative surgery for BOTs can be accepted under close follow-ups. However, survival rate of disease can be expected to be poor if malignant transformation of BOTs occurred.
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Functional roles of CTCF in breast cancer
( Sumin Oh ),( Chaeun Oh ),( Kyung Hyun Yoo ) 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.9
CTCF, Zinc-finger protein, has been identified as a multifunctional transcription factor that regulates gene expression through various mechanisms, including recruitment of other co-activators and binding to promoter regions of target genes. Furthermore, it has been proposed to be an insulator protein that contributes to the establishment of functional threedimensional chromatin structures. It can disrupt transcription through blocking the connection between an enhancer and a promoter. Previous studies revealed that the onset of various diseases, including breast cancer, could be attributed to the aberrant expression of CTCF itself or one or more of its target genes. In this review, we will describe molecular dysfunction involving CTCF that induces tumorigenesis and summarize the functional roles of CTCF in breast cancer. [BMB Reports 2017; 50(9): 445-453]
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Sumin Oh,Sunghoon Jung 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.10
The genus Arboridia Zachvatkin belongs to the tribe Erythroneurini of the subfamily Typhlocybinae (Hemiptera: Auchenorrhyncha: Cicadellidae). A total of 69 valid species have been described in the Palaearctic and Oriental region. So far, seven species of this genus have been recorded in the Korean Peninsula. In this study, we present two new species, Arboridia sp. nov. 1, Arboridia sp. nov. 2, and provide a key to the Arboridia species in the Korean Peninsula with biological information such as host plants and distributions.
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Sumin Oh,Sunghoon Jung 한국응용곤충학회 2015 한국응용곤충학회 학술대회논문집 Vol.2015 No.04
Genus Tautoneura Anufriev, 1969 (Hemiptera: Auchenorrhyncha: Cicadellidae: Typlocybinae) were recorded 59 species in the world. Among them, only 1 species: Tautoneura mori has been recorded so far in the Korean Peninsula. Tautoneura mori is known as a major pest of Mulberry in China and Japan, and we also confirmed that it appears on Mulberry in Korea. In this talk, we confirmed two new records: Tautoneura japonica, Tautoneura tricolor to the Korean typhlocybinae fauna, and we also discovered one new species to science. Additionally, we provide biological information such as host plants and distributional records, with a key to the Korean Tautoneura species. We also discuss potential status of each species as an agricultural pest concerning its biological traits.
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Oh, Sumin,Oh, Sejong Korea Genome Organization 2014 Genomics & informatics Vol.12 No.3
Gastritis is a major disease that has the potential to grow as gastric cancer. Gastric cancer is a very common cancer, and it is related to a very high mortality rate in Korea. This disease is known to have various reasons, including infection with Helicobacter pylori, dietary habits, tobacco, and alcohol. The incidence rate of gastritis has reported to differ between age, population, and gender. However, unlike other factors, there has been no analysis based on gender. So, we examined the high risk factors of gastritis in each gender in the Korean population by focusing on sex. We performed an analysis of 120 clinical characteristics and genome-wide association studies (GWAS) using 349,184 single-nucleotide polymorphisms from the results of Anseong and Ansan cohort study in the Korea Association Resource (KARE) project. As the result, we could not prove a strong relation with these factors and gastritis or gastric ulcer in the GWAS. However, we confirmed several already-known risk factors and also found some differences of clinical characteristics in each gender using logistic regression. As a result of the logistic regression, a relation with hyperlipidemia, coronary artery disease, myocardial infarction, hyperlipidemia therapy, hypotensive or antihypotensive drug, diastolic blood pressure, and gastritis was seen in males; the results of this study suggest that vascular disease has a potential association with gastritis in males.
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Sumin Oh,Bong Woo LEE,Sunghoon Jung 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.04
Grapevines are cultivated globally, and are also damaged by a large number of insect pests especially including leafhoppers. Leafhoppers are one of the important insect pests on various crops including grape. Among them, the genus Arboridia Zachvatkin (Hemiptera: Auchenorrhyncha: Cicadellidae: Typhlocybinae) was known as insect pests against grape farming. Eighty species were described in the genus in the world, and eight species were recorded in the Korean Peninsula so far, which are: Arboridia apicalis, A. kakogawana, A. koreacola, A. maculifrons, A. nigrigena, A. okamotonis, A. silvarum, A. suzukii. Among them, A. apicalis, A. kakogawana, A. maculifrons, A. nigrigena, A. suzukii have been known as important insect pests on grapes. In this talk, we propose a new species from the Korean Peninsula, and confirmed two new records: A. agrillacea and A. lunula. Additionally we present differential diagnoses of the Arboridia species damaging on grapevines for the field of applied biology.
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Perioperative and postoperative morbidity after sacrocolpopexy according to age in Korean women
( Sumin Oh ),( So Hyun Shin ),( Ji Young Kim ),( Maria Lee ),( Myung Jae Jeon ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.1
Objective This study aimed to compare perioperative and postoperative morbidity of older and younger women undergoing sacrocolpopexy (SCP). Methods A retrospective study included 271 patients who underwent laparotomic SCP for symptomatic pelvic organ prolapse from November 2008 to June 2013 at our institution. By the review of medical records, perioperative and postoperative data including the length of the surgery, estimated blood loss, blood transfusion, the length of hospital stay, wound complications and febrile morbidity were collected. In addition, cardiovascular, pulmonary, gastrointestinal, genitourinary,or neurological adverse events were retrieved. The need for an indwelling urinary catheter or performance of clean intermittent self-catheterization, mesh erosion rate and the number of days required for each were included in the postoperative outcomes. For the outcome variable analyzed in this study, the patients was dichomotized into women aged 65 and older and those younger than 65. Results One hundred and thirty-five (49.8%) patients were younger than 65 and 136 (50.2%) were aged 65 and older. Older women had higher body mass index, vaginal parity and prior surgery for hysterectomy than younger women (P<0.05). And older women had higher baseline comorbidities, such as hypertension, diabetes, cardiac disease (P<0.05), and theirAmerican society of Anesthesiologist class was higher (P<0.001). In the perioperative and postoperative complication, older group showed no differences in most of the operation-related complication rates, but gastrointestinal complication rate. Also, mesh erosion rate was not found to be significantly different between the two groups at the last visit. Conclusion Older women undergoing laparotomic SCP have similar perioperative and postoperative morbidities as younger women, suggesting surgeons can counsel older and younger women similarly in terms of operative risks.
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How and on whom to perform uterine-preserving surgery for uterine prolapse
Sumin Oh,전명재 대한산부인과학회 2022 Obstetrics & Gynecology Science Vol.65 No.4
The demand for uterine preservation in pelvic reconstructive surgery for uterovaginal prolapse is steadily increasing,and several procedures have been introduced, such as sacrospinous hysteropexy, uterosacral hysteropexy,sacrohysteropexy, and hysteropectopexy. However, the benefits and risks of uterine-preserving surgeries are notwell understood. This review discusses the current evidence surrounding uterine-preserving surgery for uterovaginalprolapse repair. This may help surgeons and patients have a balanced discussion on how and on whom to performuterine-preserving surgery. 영어
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