http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Minyoung Sin (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Induction of IL-8 in Periodontal Ligament Cells by H₂O₂
Yang-Sin Lee,Eun Jung Bak,Minyoung Kim,Wonse Park,서정택,Yun-Jung Yoo 한국미생물학회 2008 The journal of microbiology Vol.46 No.5
Periodontitis is an inflammatory disease caused by bacteria. In periodontitis, reactive oxygen species (ROS) are released from inflammatory cells in response to bacteria. Interleukin (IL)-8 is one of pro-inflammatory cytokines. To investigate the role of ROS in pathogenesis of periodontitis, we estimated the effect of H₂O₂, one of ROS, on the expression of IL-8 in human periodontal ligament (PDL) cells. PDL cells were treated with H₂O₂. IL-8 expression was determined by reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). The phosphorylation of extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (p38) and c-jun NH₂-terminal kinase (JNK) was estimated by Western blotting. Treatment with H₂O₂ at concentration of up to 250 μM increased IL-8 mRNA expression and production in a concentration-dependent manner. However, treatment with 500 μM H₂O₂ did not increase IL-8 production. Catalase, an inhibitor of H₂O₂, down-regulated the production of IL-8 induced by H₂O₂. H₂O₂ increased the phosphorylation of ERK, p38, and JNK. Pretreatment with PD98059 (ERK inhibitor), SB203580 (p38 inhibitor), or SP600125 (JNK inhibitor) decreased the IL-8 production induced by H₂O₂. These results indicate that H₂O₂ acts as an inducer of IL-8 secretion via activation of ERK, p38, and JNK in PDL cells. H₂O₂ deposited in periodontal tissue during inflammation against bacteria may accelerate tissue destruction via induction of IL-8 in PDL cells.
-
Kinematics Analysis and Motion Planning For a 7-DOF Redundant Industrial Robot Manipulator
Jayoung Kim,Minyoung Sin,Jihong Lee 제어로봇시스템학회 2011 제어로봇시스템학회 국제학술대회 논문집 Vol.2011 No.10
This paper proposes application methods for utilizing a 7-DOF robot manipulator called YH050 in industrial settings. For finding an optimal method to solve the inverse kinematics problem, we propose three methods: numerical approach, geometrical approach and combined approach for inverse kinematics solution. Also, for efficient application of the robot in a work zone, we present motion planning to avoid singularities, obstacles, and to occupy minimal workspace. In this paper, these studies are theoretically explained and then experimentally verified.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
