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RISS 인기검색어
- 검색키워드
- 저자 : Ming-Jyh Chern (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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3D Scaffold with PCL Combined Biomedical Ceramic Materials for Bone Tissue Regeneration
Ming-Jyh Chern,Liang-Yo Yang,Yung-Kang Shen,Jia-Hsiang Hung 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
Three-dimensional porous biodegradable polymer scaffolds have been widely used for tissue engineering of bone repair or regeneration. The primary function of scaffolds is to provide structure support for the cells adhesion and proliferation. This study selects the Poly-ε-caprolactone (PCL) as material, NaCl mixed with hydroxyapatite (HA) or nano-aluminum oxide (nAl2O3) for porous scaffold. This study uses the solvent casting/particulate leaching method to fabricate the porous scaffold. The authors discuss the compression mechanical properties, physical properties (porosity, moisture content, contact angle) of a pure PCL, PCL/mHA,PCL/nHA and PCL/nAl2O3 scaffolds. In vitro cell culture is used for osteoblast cell (MG63) and the microculture tetrazolium test (MTT) is undertaken in the scaffold. The scaffolds are implanted to the femur of rats and histological examination is attempted after 2 weeks. The experimental results indicate that HA and nAl2O3 can improve the hydrophilic property. In conclusion, the PCL/nHA scaffold exhibits splendid in vivo biocompatibility and osteogenesis.
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Incompressible smoothed particle hydrodynamics modeling of thermal convection
Moballa, Burniadi,Chern, Ming-Jyh,Odhiambo, Ernest Techno-Press 2013 Interaction and multiscale mechanics Vol.6 No.2
An incompressible smoothed particle hydrodynamics (ISPH) method based on the incremental pressure projection method is developed in this study. The Rayleigh-B$\acute{e}$nard convection in a square enclosure is used as a validation case and the results obtained by the proposed ISPH model are compared to the benchmark solutions. The comparison shows that the established ISPH method has a good performance in terms of accuracy. Subsequently, the proposed ISPH method is employed to simulate natural convection from a heated cylinder in a square enclosure. It shows that the predictions obtained by the ISPH method are in good agreements with the results obtained by previous studies using alternative numerical methods. A rotating and heated cylinder is also considered to study the effect of the rotation on the heat transfer process in the enclosure space. The numerical results show that for a square enclosure at, the addition of kinetic energy in the form of rotation does not enhance the heat transfer process. The method is also applied to simulate forced convection from a circular cylinder in an unbounded uniform flow. In terms of results, it turns out that the proposed ISPH model is capable to simulate heat transfer problems with the complex and moving boundaries.
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