예비언어재활사의 협력적 태도에 관한 연구

권미지 ( Miji Kwon ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.5

본 연구는 임상현장에서 직무를 수행하게 될 예비언어재활사들을 대상으로 협력적 태도를 알아보기 위함이다. 연구방법은 언어재활 전공 대학생 166명을 대상으로 온라인 설문을 실시하였다. 연구결과 첫째, 협력 태도에 대한 언어재활사의 전반적인 인식이 높게 나타났다. 둘째, 협력 태도의 하위 범주 간 모든 항목에서 유의미한 상관이 나타났다. 셋째, 예비언어재활사의 학년에 따른 협력 태도 차이 결과 모든 항목에서 유의미한 차이가 나타났다. 또한 예비언어재활사의 실습 경험 여부에 따른 협력 태도 차이 결과, ‘가족 협력 인식’에서 유의미한 차이가 나타났다. 이러한 결과를 통해 예비언어재활사들의 팀 접근에서의 상호협력의 중요성을 위한 협력 태도 교육의 기초자료가 될 것으로 사료된다. The purpose of this study is to investigate the cooperative attitude of pre-service speech-language pathologists who will perform their duties in the clinical field. As a research method, an online questionnaire was conducted targeting 166 college students majoring in speech rehabilitation. As a result of the study, first, the overall perception of pre-service speech-language pathologists on cooperative attitudes was high. Second, significant correlations were found in all items between subcategories of cooperative attitudes. Third, as a result of differences in cooperative attitudes according to grades of pre-service speech-language pathologists, significant differences were found in all items. In addition, as a result of the difference in cooperative attitude according to the practical experience of pre-service speech-language pathologists, there was a significant difference in ‘recognition of family cooperation.’ Through these results, it is thought that it will be a basic data for cooperative attitude education for the importance of mutual cooperation in the team approach of pre-service speech-language pathologists.

빅카인즈 시스템을 통한 언어치료 관련 언론보도 분석

권미지 ( Miji Kwon ),손은남 ( Eunnam Sohn ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.3

이 연구에서는 언론 뉴스기사에 보도되고 있는 언어치료에 대한 키워드 및 노출건수 등을 분석하였다. 분석 결과를 바탕으로 언어치료의 언론보도 전략 및 방향 등을 수립하는데 기초 자료를 제공하는 데 목적을 두고자 한다. 이 연구의 자료는 빅카인즈(Bigkinds)를 활용하여 최근 31년 동안의 언어치료에 대한 언론보도 1,820건을 논문 분석에 활용하였다. 첫째, 1990년대 언어치료 관련 언론보도 건수는 10년간 총 84건으로 언어치료 관련 언론보도가 매우 저조한 것을 볼 수 있었다. 둘째, 2000년대 언어치료 관련 언론보도 건수는 10년간 총 402건으로 보도되었다. 이는 전국적으로 언어치료 양성 대학 및 대학원들이 생겨났으며, 언어치료학에 대한 학문적인 발전을 도모한 시기로 분석할 수 있다. 셋째, 2010년대 언어치료 관련 언론보도 건수는 11년간 총 1,334건으로 급격히 증가하였다. 이는 언어치료 양성 대학에서의 언론 보도와 직업군으로서의 언어치료사에 대한 보도들이 증가한 것으로 파악되었다. 앞으로는 언어치료 관련 키워드 노출 건수가 많아지고, 긍정적인 연관어들이 많이 파생되어 언어치료 및 언어치료학에 대한 발전을 도모할 것을 기대한다. In this study, we understand the flow and characteristics of keywords and exposure to speech therapy that are being reported in the media. In addition, the purpose is to provide basic resources to provide language therapy direction and media reporting strategies in the future. The study’s data was utilized by Bigkinds to use 1,820 press reports on speech therapy in the last 31 years for the paper’s analysis. First, in the 1990s, there were a total of 84 press reports related to speech therapy, and the number of media reports related to speech therapy was very poor. Second, in the 2000s, a total of 402 media reports related to speech therapy were reported over a decade. This is a time when language therapy training colleges and graduate schools have sprung up across the country, and academic advances in speech therapy can be analyzed. Third, in the 2010s, the number of media reports related to speech therapy increased dramatically to a total of 1,334 over 11 years. This was seen as an increase in media coverage at the College of Speech Therapy Training and reports of speech therapists as a profession. In the future, we expect to see a lot of keyword impressions related to speech therapy, and a lot of positive associations will be derived to promote the development of speech therapy and speech therapy.

언어치료전공 대학생의 보완대체의사소통에 대한 이해도와 기대도 연구

권미지 ( Miji Kwon ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.2

본 연구의 목적은 임상현장을 앞두고 있는 예비언어재활사들을 대상으로 보완대체의사소통에 대한 이해도와 기대도를 알아보기 위함이다. 연구방법은 언어치료전공 대학생의 218명을 대상으로 설문조사를 실시하였다. 연구 결과 첫째, ‘AAC 적용은 구어발달을 방해하거나 멈추게 한다’ 문항에서 학년간 이해도 차이가 있는 것으로 나타났다. 또한 AAC 적용에 따른 이해도 차이 결과, ‘4-5세’ 연령과 ‘뇌병변 장애’ 영역에서 AAC를 주로 적용할 것으로 분석되었다. 둘째, 보완대체의사소통의 기대도에 대한 인식차이를 분석 결과, AAC 사용시 긍정적인 기대감, 언어치료사의 역할, AAC 치료방법 소개, 프로그램 개발, 부모교육의 중요성 등에 대한 긍정적인 기대도가 나타났다. 이러한 결과를 통해 임상현장에서 요구되는 보완대체의사소통 지원을 원활하게 하기 위한 프로그램을 개발하는데 기초자료가 될 것으로 사료된다. The purpose of this study is to find out the understanding and expectation of augmentative and alternative communication for preliminary speech rehabilitation practitioners facing the clinical field. As for the research method, a questionnaire survey was conducted on 218 university students majoring in speech therapy. As a result, first, there was a difference in understanding between grades in the question ‘Applying AAC impedes or stops oral development.’ In addition, the difference in understanding of the AAC application results, it was analyzed to apply the AAC mainly in the “4-5 year old” age and “erebral palsy disorder” area. Second, as a result of analyzing the difference in perception about the expectation of augmentative and alternative communication, positive expectation when using AAC, the role of a speech therapist, introduction of AAC treatment methods, program development, and the importance of parental education were revealed. It is believed that these results will serve as basic data for developing a program to facilitate the support of augmentative and alternative communication required in the clinical field.

고형암을 표적으로 한 CAR-T 치료법

권미지(Miji Kwon),박희호(Hee Ho Park) 한국생물공학회 2020 KSBB Journal Vol.35 No.2

The chimeric antigen receptor (CAR) is a receptor that introduces the specificity of the immune cell to the tumor. CAR was first developed in the mid-1980s. CARs have evolved from first-generation CARs to fourth-generation CARs. Generally, CAR-T is made by separating and activating T cells from the patient’s blood and then using virus vectors to form CARs. CAR-T has successful clinical results in the treatment of hematologic malignancies, and there are U.S. FDA-approved drugs. Although solid tumor research is being actively conducted, the results of clinical trials on solid tumor are still not as expected. Therefore, it is necessary to study CAR-T therapy, especially efficacy and stability of CAR-T cells against solid tumors.

혈액암을 표적으로 한 키메라항원수용체-T 세포 (CAR-T) 치료법

박현모(Hyunmo Park),권미지(Miji Kwon),임광석(Kwang Suk Lim),박희호(Hee Ho Park) 한국생물공학회 2020 KSBB Journal Vol.35 No.3

Immunotherapy has demonstrated significant potential for the treatment of patients with hematologic malignancies and solid tumors. Among the many immunotherapy treatments, chimeric antigen receptor-T cell (CAR-T) therapy is the most promising treatment. The CAR-T cell is an effector T cell that recognizes and eliminates specific cancer cells, independent of major histocompatibility complex molecules. Currently, CAR-T therapy has many successful clinical results for hematologic malignancies. However, CAR-T has side effects and limits on anti-cancer effectiveness and persistence. Thus, a new CAR-T model is being developed to improve these problems. Although the new CAR-T model still needs more clinical trials, recent clinical trials have reported improvements over traditional CAR-T.

예비언어재활사의 성인언어재활에 대한 인식과 요구도를 통한 교과과정 개발 방향 탐색

박현린 ( Hyunrin Park ),권미지 ( Miji Kwon ),손은남 ( Eunnam Sohn ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.6

본 연구는 성인 대상의 의사소통 평가 및 중재에 대한 예비언어재활사들의 인식과 경험을 살펴 현장의 실태를 파악하고, 이와 관련된 교육에 대한 요구도를 살펴보고자 실시되었다. 국내 4년제 대학 네 곳의 언어재활관련 학과에 재학중인 131명의 예비언어재활사의 설문지를 분석하였다. 설문지는 연구대상자 정보 5문항, 인식에 대한 문항 4문항, 교육 요구도에 대한 문항 5문항, 평가 및 중재 경험에 대한 문항 2문항으로 이루어졌다. 연구 결과, 성인언어재활에 대해 중요하다(매우 그렇다, 그렇다)고 응답한 학생이 약 90%이상이었음에도 불구하고, 평가 및 중재에 자신있다(매우 그렇다, 그렇다)고 응답한 학생이 약 26%에 불과하였다. 또한, 실습을 한 학생들 중 성인언어재활과 관련한 중재 경험이 있는 학생은 20%를 웃도는 수준이었으며, 이와 관련된 추가 교과목 개설에 대해 65% 이상이 필요하다고 응답하였다. 본 연구를 바탕으로 예비언어재활사들이 성인언어재활에 대한 중요성을 인식함에도 임상실습 수업 내에서의 경험 부족으로 인해 자신감이 결여되있음을 알 수 있었다. 대학 교육에서 성인언어재활과 관련된 실습이 효과적으로 이루어질 필요가 있을 것이다. 추후 이에 대한 전문가 집단의 질적 연구가 필요함을 제언하였다. This study was conducted to examine the perception, experience, and educational needs of pre-service SLPs for language evaluation and intervention for adults. We analyzed questionnaires from 131 pre-service SLPs enrolled in language rehabilitation-related departments at four universities. The questionnaire consisted of 5 questions about subject information, 4 questions about perception, 5 questions about educational needs, and 2 questions about evaluation and intervention experience for adults. As a result of the study, although more than 90% (strongly agree, agree) of the students who answered that speech-language rehabilitation for adults is important, only about 26% of the students who answered that they were confident in evaluation and intervention for adults. Also, only about 20% of the students who did the practice had experience with adult intervention. In addition, more than 65% of students answered that they needed additional educational program related to language rehabilitation for adults. Based on this study, it was found that although pre-service SLPs recognize the importance of language rehabilitation for adults, they lack confidence due to lack of experience in clinical practice subject. In university education, adult speech-language rehabilitation program should be effectively learned through practical subjects. In addition, we suggest that qualitative research in expert groups will be required later.

항암제 개발: 토포아이소머라제, HSP90, mTOR 및 티로신키나제 억제제

최경철(Kyoungcheol Choi),이성호(Seongho Lee),권미지(Miji Kwon),홍세영(Seyoung Hong),박희호(Hee Ho Park),임광석(Kwang Suk Lim) 한국생물공학회 2021 KSBB Journal Vol.36 No.2

Chemical anticancer drugs that have been used for a long time for the treatment of cancer have high anticancer effects and many side effects. The side effects of anticancer drugs have also affected normal cells because they induce the death of cancer cells by inhibiting or blocking essential mechanisms for cell survival. Recently, inhibitory drugs that inhibit specific mechanisms of cancer cells are receiving a lot of attention as anticancer drugs. Inhibitory drugs have less effect on normal cells by inhibiting the activity of target proteins that are overexpressed in cancer cells. Representative anticancer inhibitors among many inhibitory drugs are mTOR inhibitors, topoisomerase inhibitors, heat shock protein 90 (HSP90) inhibitors and tyrosine kinase inhibitors. For each of these inhibitor family, new candidate inhibitor drugs are continuously being developed and clinical trials are underway. In this review, we will examine the drug mechanism of each inhibitor drug, and describe the approved drugs and drugs in clinical trials.

암 치료를 위한 항체치료제에 대한 고찰: 면역항암제

유한진(HanJin Yu),홍세영(Seyoung Hong),권미지(Miji Kwon),이지현(Jihyeon Lee),박희호(Hee Ho Park),임광석(Kwang Suk Lim) 한국생물공학회 2020 KSBB Journal Vol.35 No.2

Recently, biopharmaceutical drugs take a big part in the pharmaceutical market with the development of genetic engineering. Therapeutic antibodies, one of the representative biopharmaceuticals, have strong therapeutic efficacy in various diseases such as autoimmune disease, rheumatism and cancer. Antibodies are widely used as targeted delivery systems, diagnostics and therapeutics because of their high specific recognition ability. In addition, the market for therapeutic antibodies is expanding further with the development of new biologic drugs such as biosimilar and biobetter. In particular, cancer immunotherapy has shown excellent efficacy for the treatment of cancer by regulating the immune response. In recent years, antibody-drug conjugates (ADCs), immune checkpoint inhibitors and therapeutic antibodies have been developed by many researchers and pharmaceutical companies and approved by U.S. food and drug administration as a potential strategy for the treatment of cancer. Although cancer immunotherapy has a strong therapeutic efficacy, there are still limitations to overcome such as for the treatment of solid tumor, immunogenicity and resistance. To solve these problems, new biomarkers, bispecific antibodies and combinatorial therapy with chemotherapy are being investigated. In this review, we describe the mechanism of immune response with respect to antibody therapeutics, characteristics of target cancers and discuss the potentials of cancer immunotherapy.

장애 관련 그림책 활용 의사소통장애 수업이 예비언어재활사의 교수효능감과 장애인식에 미치는 영향

박현린 ( Hyunrin Park ),손은남 ( Eunnam Sohn ),권미지 ( Miji Kwon ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.1

본 연구의 목적은 기존에 이론 중심으로 진행되는 ‘의사소통장애개론’ 교과목을 장애관련 그림책을 활용한 수업으로 설계하고 운영하는 과정을 제시하고 수업 운영의 효과를 살펴보는데 있다. 연구방법은 다음과 같다. 운영의 효과는 수업에 참여한 학습자들의 교수효능감을 측정하여 양적인 변화를 확인하고 저널쓰기를 분석하여 질적인 변화를 살피고자 하였다. 연구에 참여하는 학생은 G지역 대학교의 언어치료학과 1학년으로 장애 관련 교육의 경험이 없는 30명이었다. 장애관련 그림책 프로그램은 13주간의 프로그램으로 계획·운영되었으며, 사전·사후에 교수효능감 설문과 저널쓰기가 진행되었다. 연구결과 첫째, 예비언어재활사들은 그림책 프로그램에 참여하기 전에 비해 수업 후 유의미하게 개인적 교수효능감이 높아진 것을 알 수 있었다. 둘째, 저널쓰기를 살펴본 결과 예비언어재활사들의 장애와 관련된 지식이 확장, 그림책을 통한 장애인식의 긍정적 개선, 자기반성과 노력의지에 대한 언급이 가장 많은 것을 알 수 있었다. 본 연구를 바탕으로 예비언어재활사 양성과정에 있어서 장애관련 그림책을 이용한 다양한 프로그램 필요성을 제안하였다. 더불어 교과목의 설계 및 운영, 효과검토에 대한 제언을 기술하였다. This study proposes the redesigning of the current theory-based introductory course to communication disorders to a course that utilizes picture books related to disabilities, and looks into the effectiveness of such classes. The effectiveness was evaluated by examining quantitative changes, measured by the teaching efficacy of the learners who participated in the new type of course, and qualitative changes, achieved through the learners’ journal writing. A total of 30 freshmen from the Department of Communication Disorders of an undisclosed regional university who had no prior disability-related education were studied. The program was 13 weeks long, and a questionnaire on teaching efficacy and journal writing was conducted before and after the program. The results of the study are as follows: first, prospective speech and language therapists’ personal teaching efficacy significantly increased after the program; and second, examination of their written journals showed that the therapist candidates’ knowledge related to disabilities had expanded, their awareness of disabilities was positively enhanced through picture books, and self-reflection and willingness were mentioned most often. This study suggests the necessity of various programs that utilize picture books related to disabilities in the curriculum for prospective speech and language therapists. Furthermore, detailed proposals for the design and implementation of the program are laid out and the analyzed evaluation is explained.

언어재활사의 코로나19에 대한 불안도와 예방행위 실천도와의 관계

박현린 ( Hyunrin Park ),손은남 ( Eunnam Sohn ),권미지 ( Miji Kwon ) 인문사회 21 2023 인문사회 21 Vol.14 No.1

연구 목적: 언어재활사의 감염병에 대한 불안도와 예방행위 실천도를 파악하여 신종감염병 대응전략 및 신종감염병 예방 교육을 수립하기 위한 기초자료를 제공하기 위함이다. 연구 방법: 언어재활사들에게 설문을 배부하여 회수된 167부로 설문연구를 실시하였다. 연구 결과: 첫째, 신종감염병에 대한 언어재활사들의 불안도의 전체 평균은 3.7점, 예방행위 실천도의 전체 평균은 4.1점으로 나타났다. 둘째, 언어재활사의 불안도와 예방행위 실천도에서 정적 상관이 나타났다. 셋째, 코로나19 감염 경험 유무에 따라 감염병에 대한 예방행위 실천도에서 집단 간 유의미한 차이가 나타났다. 결론 및 제언: 본 연구를 통해 언어재활사들의 감염병에 대한 불안도와 예방행위 실천도를 살펴볼 수 있었다. 이를 바탕으로 언어재활사를 위한 신종감염병과 관련하여 예방행위 실천 교육 및 언어재활사의 불안도를 낮추기 위한 실제적인 방안 마련 등의 구체적인 변화가 필요할 것이다. The purpose of this study is to identify the level of anxiety and preventive behaviors about infectious diseases in SLPs (speech-language pathologists). Based on the results of this study, we intend to provide basic data for establishing new infectious disease response strategies and prevention education. A survey was conducted with 167 copies collected by distributing questionnaires to SLPs. First, the overall average of SLPs’ anxiety about new infectious diseases was 3.7 points, and the overall average of preventive behavior practice was 4.1 points. Second, there was a positive correlation between the SLPs’s anxiety and preventive behavior practice. Third, there was a significant difference between groups in the preventive behavior practice of infectious diseases according to the experience of COVID-19 infection. Through this study, it was possible to examine the level of preventive behavior practice and anxiety about infectious diseases of SLPs. Based on this, it will be necessary to make concrete changes, such as education for practicing preventive behaviors in relation to new infectious diseases for SLPs, and preparation of practical measures to lower the level of anxiety of SLPs.