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Marcelle Michelotti Bettoni,Átila Francisco Mogor,Volnei Pauletti,Nieves Goicoechea 한국원예학회 2017 Horticulture, Environment, and Biotechnology Vol.58 No.5
The combined application of humic substances and mycorrhizal inocula under increased CO2 in the air is apromising horticultural technique for improving the quality of greenhouse-grown onion seedlings. The objective of thisstudy was to evaluate if the development and qualitative characteristics of bulbs from the yellow onion Allium cepaL. Alfa São Francisco improved with the application of the abovementioned agronomic, biotic, and environmentalfactors. The lowest dry matter was achieved in bulbs of onions not inoculated with mycorrhizal fungi, non-amendedwith humic acids (HA), and grown at ambient CO2. Mycorrhizal inoculation significantly increased bulb biomass inplants cultivated at ambient CO2, and not fertilized with HA, which may be a consequence of the enhanced acidphosphatase activity in roots. The application of HA always increased bulb dry matter, which were more evident atelevated rather than ambient CO2 conditions and correlated with improved acid phosphatase activity in the plants atelevated CO2. Mycorrhizal inoculation, HA supplementation, and elevated CO2 in the air had an additive effect ofincreasing the content of soluble sugars, proteins, and phenolics in bulbs. While high levels of sugars and proteinsenhanced the energetic value of onions, the increase in phenolics improved their antioxidant properties. The tripleinteraction between mycorrhization, HA fertilization, and elevated CO2 also increased the ratio between soluble solidsand total titratable acidity, which may enhance the perception of sweetness and make onions more pleasant forconsumption.
Algorithmic approach to the lymphatic leak after vascular reconstruction: a systematic review
Nicksic, Peter John,Condit, Kevin Michael,Nayar, Harry Siva,Michelotti, Brett Foster Korean Society of Plastic and Reconstructive Surge 2021 Archives of Plastic Surgery Vol.48 No.4
Background To date, there are no consensus guidelines for management of lymphatic leak in groin vascular reconstruction patients. The goal of this study is to review the relevant literature to determine alternatives for treatment and to design an evidence-based algorithm to minimize cost and morbidity and maximize efficacy. Methods A systematic review of the literature was conducted per Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. Two independent reviewers applied agreed-upon inclusion and exclusion criteria to eligible records. Studies that included patients who underwent groin dissection for oncologic diagnoses and level 5 data were excluded. Interventions were then categorized by efficacy using predetermined criteria. Results Our search yielded 333 records, of which eight studies were included. In four studies, the success of lymphatic ligation ranged from 75% to 100%, with average days to resolution ranging from 0 to 9. Conservative management in the form of elevation, compression, and bedrest may prolong time to resolution of lymphatic leak (14-24 days) and therefore cost. Conclusions The majority of patients should be offered early operative intervention in the form of lymphatic ligation with or without a primary muscle flap. If the patient is not an operative candidate, a trial of conservative management should be attempted before other nonsurgical interventions.
Yuan, Langtian,Seo, Jin-Soo,Kang, Nam Sook,Keinan, Shahar,Steele, Sarah E.,Michelotti, Gregory A.,Wetsel, William C.,Beratan, David N.,Gong, Young-Dae,Lee, Tong H.,Hong, Jiyong Royal Society of Chemistry 2009 Molecular bioSystems Vol.5 No.9
<P>From a screen of small molecule libraries to identify potential therapeutics for psychostimulant abuse, 3-hydroxy-2-(3-hydroxyphenyl)-4<I>H</I>-1-benzopyran-4-ones were shown to be isoform-selective PKC-ζ inhibitors.</P> <P>Graphic Abstract</P><P>3-hydroxy-2-(3-hydroxyphenyl)-4<I>H</I>-1-benzopyran-4-ones were shown to be isoform-selective PKC-ζ inhibitors. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b903036k'> </P>