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- 저자 : Meng Zhaojun (검색결과 4 건)
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Qingli Meng,Kejun Wang,Xiallei Liu,Haishen Zhou,Li Xu,Zhaojun Wang,Meiying Fang 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.4
Objective: The aim of this study is to identify genomic regions or genes controlling growth traits in pigs. Methods: Using a panel of 54,148 single nucleotide polymorphisms (SNPs), we performed a genome-wide Association (GWA) study in 562 pure Yorshire pigs with four growth traits: average daily gain from 30 kg to 100 kg or 115 kg, and days to 100 kg or 115 kg. Fixed and random model Circulating Probability Unification method was used to identify the associations between 54,148 SNPs and these four traits. SNP annotations were performed through the Sus scrofa data set from Ensembl. Bioinformatics analysis, including gene ontology analysis, pathway analysis and network analysis, was used to identify the candidate genes. Results: We detected 6 significant and 12 suggestive SNPs, and identified 9 candidate genes in close proximity to them (suppressor of glucose by autophagy [SOGA1], R-Spondin 2 [RSPO2], mitogen activated protein kinase kinase 6 [MAP2K6], phospholipase C beta 1 [PLCB1], rho GTPASE activating protein 24 [ARHGAP24], cytoplasmic polyadenylation element binding protein 4 [CPEB4], GLI family zinc finger 2 [GLI2], neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 [NYAP2], and zinc finger protein multitype 2 [ZFPM2]). Gene ontology analysis and literature mining indicated that the candidate genes are involved in bone, muscle, fat, and lung development. Pathway analysis revealed that PLCB1 and MAP2K6 participate in the gonadotropin signaling pathway and suggests that these two genes contribute to growth at the onset of puberty. Conclusion: Our results provide new clues for understanding the genetic mechanisms underlying growth traits, and may help improve these traits in future breeding programs.
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Cong Feng,Zhaojun Yang,Chuanhai Chen,Jinyan Guo,Hailong Tian,Fanning Meng 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.6
Accuracy retention is an important performance index of CNC machine tools. At present, research on the evaluation of machining accuracy retention of CNC machine tools mainly focuses on accuracy value of a fixed time point or different time periods, but studies on the fluctuation degree of degradation trajectory related to time change are limited. Extracting simple and effective degradation characteristics of machining accuracy and then evaluating machining accuracy retention considering fluctuation of degradation trajectory are necessary. The volume error model of CNC machine tools is established on the basis of multibody system theory in this study. Three-dimensional volume error vector is transformed into one-dimensional machining accuracy degradation by calculating offset distance between spatial error and origin points. Degradation data obtained via regular measurement and calculation are used to establish the complete degradation trajectory model of the CNC machine tools machining accuracy using radial basis function interpolation method according to the fluctuation degree of degradation trajectory, and concepts of average degradation rate and average degradation amount are defined. Lastly, examples showed that these two indicators can intuitively reflect fluctuation degree of machining accuracy degradation of CNC machine tools and effectively and quantitatively evaluate accuracy retention of CNC machine tools. The quantitative evaluation method of accuracy retention of CNC machine tools defined in this study considers the fluctuation degree of accuracy degradation trajectory. The quantitative evaluation index of accuracy retention demonstrates satisfactory engineering application because it can reflect not only the accuracy change of a single machine tool but also accurately compare the accuracy retention between different machine tools.
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Zhang Jie,Jiang Dun,Dong Xiaowen,Meng Zhaojun,Yan Shanchun 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4
To investigate the accumulation patterns of Cd and/or Pb in various body parts, organs and tissues of the Asian gypsy moth (Lymantria dispar) larvae under Cd and/or Pb stress, Cd and Pb treated artificial diets were used to feed the larvae in the current study. These larval body parts/organs/tissues included the heads, integuments (body walls), alimentary canals, fat bodies and hemolymphs. Our results showed that under Cd and/or Pb stress, their accumulations in larval body parts/organs/tissues were significantly higher than those in the control, with the amounts of tested metals in the fat bodies and hemolymphs and alimentary canals being significantly higher than those in the heads and integuments. Under the single Cd (0, 7.5, 10.5 mg/kg) or Pb stress (0, 55, 90, 125 mg/kg), the accumulations of these heavy metals were positively correlated with their concentrations in diets. Under the combined stress (Cd × Pb), the Cd accumulation at the lower Pb concentrations was higher than that at higher Pb concentrations for the body parts/organs/tissues, similar effects of Cd concentrations on Pb accumulations were also recorded. These results clearly showed that Cd and/or Pb were accumulated in various body parts/organs/tissues at different levels under the heavy metal stress. And accumulations of Pb/Cd were positively correlated with their concentrations in the diets under the single stress. Under the combined stresses, Cd and Pb had synergistic effects at low concentrations whereas antagonistic effects at high concentrations. The accumulations of Cd and/or Pb in the gypsy moth larvae affects normal physiological and biochemical functions, and thus affects their growth and development.
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Preparation of mesoporous silica from coal slag and its metal ion adsorption behavior
Xinying Zhang,Yu Wu,Xuefang Li,Xianlong Meng,Huihu Shi,Zhaojun Wu,Jianbin Zhang 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.5
A novel mesoporous silica (MS) with the high specific surface area up to 1,199m2/g was prepared from coal slag by SO3 2 leaching and hydrothermal synthesis. Its application in metal ion removal was explored using Pb2+, Cu2+, Co2+ and Cd2+ as the model ions. The effects of adsorption time, pH, initial metal ion concentration, adsorbent dosage and adsorption temperature on the metal ion adsorption behaviors of the as-prepared MS were systematically, and the maximum adsorption capacities were measured to be 55.76mg·g1, 33.49mg·g1, 24.29mg·g1 and 22.98mg· g1 for Pb2+, Cu2+, Co2+ and Cd2+, respectively. The metal ion adsorption on the as-prepared MS followed pseudo-second- order kinetics, and the adsorption isotherm fitted the Langmuir isotherm model, indicating that the adsorption was spontaneous, endothermic and enthalpy driven.
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