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Azam Eskandari,Shahrokh Nasseri,Hamid Gholamhosseinian,Sare Hosseini,Mohammad Javad Keikhai Farzaneh,Alireza Keramati,Maryam Naji,Atefeh Rostami,Mehdi Momennezhad 대한방사선종양학회 2020 Radiation Oncology Journal Vol.38 No.1
Purpose: The present study was conducted to compare dosimetric parameters for the heart and left lung between free breathing (FB) and deep inspiration breath hold (DIBH) and determine the most important potential factors associated with increasing the lung dose for left-sided breast radiotherapy using image analysis with 3D Slicer software. Materials and Methods: Computed tomography-simulation scans in FB and DIBH were obtained from 17 patients with left-sided breast cancer. After contouring, three-dimensional conformal plans were generated for them. The prescribed dose was 50 Gy to the clinical target volume. In addition to the dosimetric parameters, the irradiated volumes and both displacement magnitudes and vectors for the heart and left lung were assessed using 3D Slicer software. Results: The average of the heart mean dose (Dmean) decreased from 5.97 to 3.83 Gy and V25 from 7.60% to 3.29% using DIBH (p < 0.001). Furthermore, the average of Dmean for the left lung was changed from 8.67 to 8.95 Gy (p = 0.389) and V20 from 14.84% to 15.44% (p = 0.387). Both of the absolute and relative irradiated heart volumes decreased from 42.12 to 15.82 mL and 8.16% to 3.17%, respectively (p < 0.001); however, these parameters for the left lung increased from 124.32 to 223.27 mL (p < 0.001) and 13.33% to 13.99% (p = 0.350). In addition, the average of heart and left lung displacement magnitudes were calculated at 7.32 and 20.91 mm, respectively. Conclusion: The DIBH is an effective technique in the reduction of the heart dose for tangentially treated left sided-breast cancer patients, without a detrimental effect on the left lung.
Seyed-Mostafa Razavi,Sharareh Gholamin,Ali Eskandari,Nakta Mohsenian,Amir Ghorbanihaghjo,Abbas Delazar,Nadereh Rashtchizadeh,Maryam Keshtkar-Jahromi,Hassan Argani 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.3
Hyperlipidemia can lead to atherosclerosis by lipoprotein deposition inside the vessel wall and oxidative stress induction that leads to the formation of atherosclerotic plaque. Oxidized low-density lipoprotein particles (Ox-LDL) have a key role in the pathogenesis of atherosclerosis. The lipid-lowering properties and antioxidants of the grape seed can be beneficial in atherosclerosis prevention. We conducted a randomized double-blind placebo-controlled crossover clinical trial. Fifty-two mildly hyperlipidemic individuals were divided into two groups that received either 200 mg/day of the red grape seed extract (RGSE) or placebo for 8 weeks. After an 8-week washout period, the groups were crossed over for another 8 weeks. Lipid profiles and Ox-LDL were measured at the beginning and the end of each phase. RGSE consumption reduced total cholesterol (−10.68±26.76 mg/dL, P=.015), LDL cholesterol (−9.66±23.92 mg/dL, P=.014), and Ox-LDL (−5.47±12.12 mg/dL, P=.008). While triglyceride and very low–density lipoprotein cholesterol were decreased and high-density lipoprotein cholesterol was increased by RGSE, the changes were not statistically significant. RGSE consumption decreases Ox-LDL and has beneficial effects on lipid profile—consequently decreasing the risk of atherosclerosis and cardiovascular disorders—in mild hyperlipidemic individuals.
Abdolreza Moghadassi,Shakiba Ghohyei,Samaneh Bandehali,Morteza Habibi,Maryam Eskandari 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.3
Cuprous oxide nanoparticles (Cu2O) were synthesized by electrochemical method and as an add-on toconstruct polyethersulfone (PES) nanofiltration (NF) membranes. Field emission scanning electron microscopy (FESEM),3D surface images, X-ray diffraction (XRD) analysis, and Fourier transform infrared (FTIR) spectroscopy were utilizedto indicate membranes and nanoparticles. Membranes were evaluated by tests of water content, porosity, contact angle,salt rejection, water flux and average pore size measurements. The results show the enhancement of surface hydrophilicityby the addition of Cu2O nanoparticles. The highest unalloyed water flux was obtained by membrane, including0.05 wt% Cu2O nanoparticles, and the highest rejection was revealed by a membrane containing 2 wt% Cu2Onanoparticles. The Na2SO4 rejection reached 66.94%, which was significantly higher than the bare PES membrane. Thisperformance may be owing to increased Na2SO4 adsorption sites. The heavy metals rejection of CrSO4, Pb(NO3)2, andCu (NO3)2 increased 79.38%, 85.08%, and 81% for the M5 membrane, respectively, while it was 45%, 46%, and 49% forbare membrane, respectively. Furthermore, the flux of unalloyed water increased from 9.78 L/m2·h on the pure PESmembrane to 36.78 L/m2·h on the M1 membrane. The decrease of surface roughness and also the increase of hydrophilicgroups improved the antifouling properties of the membranes.