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RISS 인기검색어
- 검색키워드
- 저자 : Marina Selina (검색결과 3 건)
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The acute and sub-acute toxicity of C<sub>60</sub>/PVP complex in vivo
Dumpis, Marina A.,Iljin, Viktor V.,Litasova, Elena V.,Nikolaev, Dmitry N.,Bulion, Valentina V.,Krylova, Irina B.,Okunevich, Irina V.,Rodionova, Olga M.,Safonova, Albina F.,Selina, Elena N.,Piotrovsky, Techno-Press 2016 Advances in nano research Vol.4 No.3
The detailed study of acute and sub-acute toxicity of the complex polyvinylpyrrolidon (PVP 20 kDa)-wrapped fullerene $C_{60}$ after intraperitoneal (ip) administration was carried out on adult male Wistar rats. The $LD_{50}$ value of $C_{60}/PVP$ complex was found to be 7, 8 g/kg. In sub-acute study which lasted for 30 days the rats were exposed to daily administration of the complex in the doses of 350 or 700 mg/kg. All animals survived during the study and had no significant changes in clinical signs, organ weight, hematological and biochemical parameters of blood. The electrophysiological properties of myocardium and the excretory function of kidneys remained normal. Histological analysis of liver, kidney and spleen at the end of the study also did not demonstrate toxic alterations. It was thus established that intraperitoneal administration of complex $C_{60}/PVP$ has no toxic effect. These results suggest that $C_{60}/PVP$ has no acute and sub-acute toxicity and is a perspective substance for potential application in biology and medicine.
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On Conditions of Phytoplankton Blooms in the Coastal Waters of the North-Western East/Japan Sea
Zuenko, Yury,Selina, Marina,Stonik, Inna The Korean Society of Oceanography 2006 Ocean science journal Vol.41 No.1
Seasonal changes of abundance of the main phytoplankton groups of species (diatoms, dinoflagellates, chrysophytes, small flagellates and cryptophytes) and a set of environmental parameters were investigated in coastal and pre-estuarine waters of Peter the Great Bay (East/Japan Sea) in May-October of 1998 and 1999. Three periods of mass development were revealed: spring, summer and autumn blooms, with successive change of species. The conditions favourable for each group of species were determined. Driving mechanisms of the succession include nutrients transport through seasonal pycnocline by turbulent mixing, terrestrial nutrients supply by monsoon floods, nutrients supply by upwellings, and light control by the thickness of upper mixed layer. Summer succession could be explained by a simple SST-MLD diagram similar to Pingree S-kh diagram with sea surface temperature as indicator of stratification (S) and mixed layer depth as indicator of light availability (kh).
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On Conditions of Phytoplankton Blooms in the Coastal Waters of the North-Western East/Japan Sea
Yury Zuenko,Marina Selina,Inna Stonik 한국해양과학기술원 2006 Ocean science journal Vol.41 No.1
changes of abundance of the main phytoplankton groups of species (diatoms, dinoflagellates, chrysophytes, small flagellates and cryptophytes) and a set of environmental parameters were investigated in coastal and pre-estuarine waters of Peter the Great Bay (East/Japan Sea) in May-October of 1998 and 1999. Three periods of mass development were revealed: spring, summer and autumn blooms, with successive change of species. The conditions favourable for each group of species were determined. Driving mechanisms of the succession include nutrients transport through seasonal pycnocline by turbulent mixing, terrestrial nutrients supply by monsoon floods, nutrients supply by upwellings, and light control by the thickness of upper mixed layer. Summer succession could be explained by a simple SST-MLD diagram similar to Pingree S-kh diagram with sea surface temperature as indicator of stratification (S) and mixed layer depth as indicator of light availability (kh).
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