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      • KCI등재

        EXISTENCE OF THE SOLUTION OF COUNTABLY INFINITE SYSTEM OF DIFFERENTIAL EQUATIONS IN SEQUENCE SPACES m<sup>p</sup>(𝜙) AND n<sup>p</sup>(𝜙) WITH THE HELP OF MEASURE OF NON-COMPACTNESS

        KHAN, MOHD SHOAIB,UDDIN, IZHAR,LOHANI, Q.M. DANISH The Korean Society for Computational and Applied M 2019 Journal of applied mathematics & informatics Vol.37 No.5

        The Banach spaces $m^p(\phi)$ and $n^p(\phi)$ are very important sequence spaces related to $l_p$, which were defined to fill the gaps between $l_p(1{\leq}p{\leq}{\infty})$. In this paper, we investigated the solubility of the infinite system of differential equations in $m^p(\phi)$ and $n^p(\phi)$ by proving related theorems. Moreover, one example has been included for the justification of the claim of this paper.

      • KCI등재

        PROXIMITY POINTS FOR CYCLIC 2-CONVEX CONTRACTION MAPPINGS

        M. S. Khan,M. Menaka,Geno Kadwin Jacob,M. Marudai 경남대학교 기초과학연구소 2020 Nonlinear Functional Analysis and Applications Vol.25 No.1

        In this paper, the existence of proximity point for cyclic 2-convex contractionmappings, weakly cyclic 2-convex contraction mappings and M-weakly cyclic 2-convex con-traction mappings are proved in the metric space setting. Our result is an natural general-ization to result discussed in Istraescu [6].

      • Novel Ag@TiO<sub>2</sub> nanocomposite synthesized by electrochemically active biofilm for nonenzymatic hydrogen peroxide sensor

        Khan, M.M.,Ansari, S.A.,Lee, J.,Cho, M.H. Elsevier 2013 Materials science & engineering. C, Materials for Vol.33 No.8

        A novel nonenzymatic sensor for H<SUB>2</SUB>O<SUB>2</SUB> was developed based on an Ag@TiO<SUB>2</SUB> nanocomposite synthesized using a simple and cost effective approach with an electrochemically active biofilm. The optical, structural, morphological and electrochemical properties of the as-prepared Ag@TiO<SUB>2</SUB> nanocomposite were examined by UV-vis spectroscopy, X-ray diffraction, transmission electron microscopy and cyclic voltammetry (CV). The Ag@TiO<SUB>2</SUB> nanocomposite was fabricated on a glassy carbon electrode (GCE) and their electrochemical performance was analyzed by CV, differential pulse voltammetry and electrochemical impedance spectroscopy. The Ag@TiO<SUB>2</SUB> nanocomposite modified GCE (Ag@TiO<SUB>2</SUB>/GCE) displayed excellent performance towards H<SUB>2</SUB>O<SUB>2</SUB> sensing at -0.73V in the linear response range from 0.83μM to 43.3μM, within a detection limit and sensitivity of 0.83μM and ~65.2328+/-0.01μAμM<SUP>-1</SUP>cm<SUP>-2</SUP>, respectively. In addition, Ag@TiO<SUB>2</SUB>/GCE exhibited good operational reproducibility and long term stability.

      • SCISCIESCOPUS

        Metal-organic frameworks as efficient catalytic systems for the synthesis of 1,5-benzodiazepines from 1,2-phenylenediamine and ketones

        Timofeeva, M.N.,Panchenko, V.N.,Prikhod'ko, S.A.,Ayupov, A.B.,Larichev, Yu.V.,Khan, Nazmul Abedin,Jhung, Sung Hwa Academic Press 2017 Journal of catalysis Vol.354 No.-

        <P><B>Abstract</B></P> <P>Benzodiazepines and their derivatives are a very important class of nitrogen-containing heterocyclic compounds with biological activity that are widely used in medicine. In this study, we demonstrated synthesis of 1,5-benzodiazepines from 1,2-phenylenediamine and ketones (acetone, cyclohexanone, acetophenone, methyl ethyl ketone) in the presence of isostructural porous metal-benzenetricarboxylates of the families MIL-100(M) (M: V<SUP>3+</SUP>, Al<SUP>3+</SUP>, Fe<SUP>3+</SUP> and Cr<SUP>3+</SUP>) and three porous aluminium trimesates Al-BTCs (MIL-96(Al), MIL-100(Al) and MIL-110(Al)). A combination of catalytic, theoretical and physicochemical methods showed that reaction rates and yields of 1,5-benzodiazepines were adjusted by the type of metal ions and accessibility of active sites. The yield of 1,5-benzodiazepines in the presence of MIL-100(M) was comparable with zeolites, such as HY, H-ZSM−5, β-zeolite and heulandite.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Synthesis of 1,5-benzodiazepines over MIL-100(M), MIL-110 and MIL-96 was studied. </LI> <LI> Effect of Brønsted and Lewis acidity on MIL’s performance was investigated. </LI> <LI> Lewis acidity of MIL-100(Fe, Cr, Al, V) was studied by EPR spectroscopy. </LI> <LI> The type of M<SUP>3+</SUP>(Al, Fe, Cr, V) and structure of MILs affect the yield of product. </LI> <LI> MIL-100(M) samples perform well in compared with zeolites. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재후보

        Comparison of Resistance Level to Cotton leaf curl virus (CLCuV)Among Newly Developed Cotton Mutants and Commercial Cultivars

        KhalidP.Akhtar,AzeemI.Khan,M.Hussain 한국식물병리학회 2002 Plant Pathology Journal Vol.18 No.4

        Four newly developed cotton mutants (M-111, M-7662, M-358 and M-218) were compared for their resistance against Cotton leaf curl virus (CLCuV) together with commercial resistant (CIM-443, CIM-482, CIM-473, FH-900 and FH-901) and susceptible (S-12) varieties by artificial inoculation through grafting and under natural field conditions. Infectivity and success of grafting were 100% in all cases. None of the grafted plants were found immune or asymptomatic. All the grafted mutants and most of their single plant progeny rows (SPPRs) showed highly resistant responses as the symptoms displayed by these mutants were milder than the commercial cultivars. Grafted mutants also had delayed disease reactions as they took more time (25-30 days) to produce disease symptoms, as compared with resistant commercial varieties that produced disease 18-22 days after inoculation. Growth of the grafted SPPRs of tested mutants was normal, which is an indication that there will be no production losses. Observations under natural infestation of whitefly showed that two SPPRs of M-11/CE and M-7662-1/2 and one resistant variety CIM-443 exhibited slight incidence of disease, while one SPPR of M-11/59 and S-12 were moderately susceptible and highly susceptible with 21% and 97.1% disease incidence, respectively. This study also showed that plants displaying more disease symptoms through grafting were easily infected under natural conditions. These results suggest that preference should be given to those plants that exhibited highly resistant responses after artificial inoculation.

      • SCIEKCI등재

        Comparison of Resistance Level to Cotton leaf curl virus(CLCuV) Among Newly Developed Cotton Mutants and Commercial Cultivars

        Akhtar, Khalid P.,Khan, Azeem I.,Hussain, M.,Khan, M.S.I. The Korean Society of Plant Pathology 2002 Plant Pathology Journal Vol.18 No.4

        Four newly developed cotton mutants (M-111, M-7662, M-358 and M-218) were compared for their resistance against Cotton leaf curl virus(CLCuV) together with commercial resistant (CIM-443, CIM-482, CIM-473, FH-900 and FH-901) and susceptible (5-12) varieties by artificial inoculation through grafting and under natural field conditions. Infectivity and success of grafting were 100% in all cases. None of the grafted plants were found immune or asymptomatic. All the grafted mutants and most of their single plant progeny rows (SPPRs) showed highly resistant responses as the symptoms displayed by these mutants were milder than the commercial cultivars. Grafted mutants also had delayed disease reactions as they took more time (25-30 days) to produce disease symptoms, as compared with resistant commercial varieties that produced disease 18-22 days after inoculation. Growth of the grafted SPPRs of tested mutants was normal, which is an indication that there will be no production losses. Observations under natural infestation of whitefly showed that two SPPRs of M-ll/CE and M-7662-1/2 and one resistant variety CIM-443 exhibited slight incidence of disease, while one SPPR of M-l1/59 and S-12 were moderately susceptible and highly susceptible with 21% and 97.l% disease incidence, respectively. This study also showed that plants displaying more disease symptoms through grafting were easily infected under natural conditions. These results suggest that preference should be given to those plants that exhibited highly resistant responses after artificial inoculation.

      • Potential antifilarial activity of the fruit, leaf and stem extract of Melia azedarach Linn. on cattle filarial parasite Setaria cervi in vitro

        Ahmed, Qamar U.,Zaidi, S.M.K.R.,Kaleem, M.,Khan, N.U.,Singhal, K.C. Kyung Hee Oriental Medicine Research Center 2006 Oriental pharmacy and experimental medicine Vol.6 No.2

        The effect of aqueous and alcoholic extracts of the fruit, leaf and stem of Melia azedarach Linn. (Meliaceae) on the spontaneous movements of both the whole worm and the nerve-muscle (n.m.) preparation of Setaria (S.) cervi and on the survival of microfilariae in vitro was studied. Alcoholic extracts of fruit, leaf and stem caused inhibition of the spontaneous movements of the whole worm and the n.m. preparation of S. cervi, while only aqueous extract of fruit caused inhibition of the spontaneous movements of the whole worm and the n.m. preparation of S. cervi. The initial stimulatory effect was not observed by the aqueous and alcoholic extracts of fruit on n.m. preparation. The concentrations required to inhibit the movements of the whole worm and n.m. preparation for alcoholic extracts of fruit, leaf and stem were 250, $40\;{\mu}g/ml$; 280, $40\;{\mu}g/ml$ and 270, $25\;{\mu}g/ml$ respectively, whereas an aqueous extract of fruit caused inhibition of whole worm and n.m. preparation at $200\;{\mu}g/ml$ and $40\;{\mu}g/ml$ respectively. Alcoholic extracts of the fruit, leaf and stem and aqueous extract of the fruit of M. azedarach caused concentration related inhibition on the survival of microfilariae (m.f.) of S. cervi. The $LC_{50}$ and $LC_{90}$ as observed after 6 h were found to be 5, 15, 10, 20 ng/ml and 10, 25, 20 and 35 ng/ml, respectively. This work was conducted in view of the exploration of potential antifilarial herbal drug.

      • KCI등재

        Reparative, Neuroprotective and Anti-neurodegenerative Effects of Granulocyte Colony Stimulating Factor in Radiation-Induced Brain Injury Model

        khan Gürkan,Özüm Atasoy,Nilsu Çini,İbrahim Halil Sever,Bahattin Özkul,khan Yaprak,Cansın Şirin,Yiğit Uyanıkgil,Ceren Kızmazoğlu,Mümin Alper Erdoğan,Oytun Erbaş 대한신경외과학회 2023 Journal of Korean neurosurgical society Vol.66 No.5

        Objective : This animal model aimed to compare the rat group that received brain irradiation and did not receive additional treatment (only saline) and the rat group that underwent brain irradiation and received Granulocyte colony stimulating factor (G-CSF) treatment. In addition, the effects of G-CSF on brain functions were examined by magnetic resonance (MR) imaging and histopathologically. Methods : This study used 24 female Wistar albino rats. Drug administration (saline or G-CSF) was started at the beginning of the study and continued for 15 days after whole-brain radiotherapy (WBRT). WBRT was given on day 7 of the start of the study. At the end of 15 days, the behavioral tests, including the three-chamber sociability test, open field test, and passive avoidance learning test, were done. After the behavioral test, the animals performed the MR spectroscopy procedure. At the end of the study, cervical dislocation was applied to all animals. Results : G-CSF treatment positively affected the results of the three-chamber sociability test, open-space test and passive avoidance learning test, cornu Ammonis (CA) 1, CA3, and Purkinje neuron counts, and the brain levels of brain-derived neurotrophic factor and postsynaptic density protein-95. However, G-CSF treatment reduced the glial fibrillary acidic protein immunostaining index and brain levels of malondialdehyde, tumor necrosis factor-alpha, nuclear factor kappa-B, and lactate. In addition, on MR spectroscopy, G-CSF had a reversible effect on brain lactate levels. Conclusion : In this first designed brain irradiation animal model, which evaluated G-CSF effects, we observed that G-CSF had reparative, neuroprotective and anti-neurodegenerative effects and had increased neurotrophic factor expression, neuronal counts, and morphology changes. In addition, G-CSF had a proven lactate-lowering effect in MR spectroscopy and brain materials.

      • SCOPUSKCI등재

        Momordica charantia and Allium sativum : Broad Spectrum Antibacterial Activity

        Khan, M.R.,Omoloso, A.D. The Korean Society of Pharmacognosy 1998 생약학회지 Vol.29 No.3

        In the Asian sub-continent Momordica charantia and Allium sativum are extensively used as food and are popular in herbal medicine. The two were screened against 15 pathogens and both exhibited broard spectrum antimicrobial activity. As compared to the standard antibiotics, M. charantia demonstrated broader and higher level of activity against most of the organisms. On the other hand A. sativum showed comparable activity to the standard antibiotics. Both M. Charantia and A. sativum are proposed as non toxic, safe, broad spectrum antibacterial agents.

      • KCI등재

        Transient Multipath routing protocol for low power and lossy networks

        ( M Ali Lodhi ),( Abdul Rehman ),( Meer M Khan ),( Muhammad Asfand-e-yar ),( Faisal Bashir Hussain ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.4

        RPL routing protocol for low-power and lossy networks is an Internet Engineering Task Force (IETF) recommended IPv6 based protocol for routing over Low power Lossy Networks (LLNs). RPL is proposed for networks with characteristics like small packet size, low bandwidth, low data rate, lossy wireless links and low power. RPL is a proactive routing protocol that creates a Directed Acyclic Graph (DAG) of the network topology. RPL is increasingly used for Internet of Things (IoT) which comprises of heterogeneous networks and applications. RPL proposes a single path routing strategy. The forwarding technique of RPL does not support multiple paths between source and destination. Multipath routing is an important strategy used in both sensor and ad-hoc network for performance enhancement. Multipath routing is also used to achieve multi-fold objectives including higher reliability, increase in throughput, fault tolerance, congestion mitigation and hole avoidance. In this paper, M-RPL (Multi-path extension of RPL) is proposed, which aims to provide temporary multiple paths during congestion over a single routing path. Congestion is primarily detected using buffer size and packet delivery ratio at forwarding nodes. Congestion is mitigated by creating partially disjoint multiple paths and by avoiding forwarding of packets through the congested node. Detailed simulation analysis of M-RPL against RPL in both grid and random topologies shows that M-RPL successfully mitigates congestion and it enhances overall network throughput.

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