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      • Optimization Model of Reliable Data Storage in Cloud Environment Using Genetic Algorithm

        Feng Liu,Haitao Wu,Xiaochun Lu,Xiyang Liu 보안공학연구지원센터 2014 International Journal of Grid and Distributed Comp Vol.7 No.6

        Massive data storage is one of the great challenges for cloud computing service, and reliable storage of sensitive data directly affects quality of storage service. In this paper, based on analysis of data storage process in cloud environment, the cost of massive data storage is considered to be comprised of data storage price, data migration and communication; and the storage reliability consists of data transmission reliability and hardware dependability. A multi-objective optimization model for reliable massive storage is proposed, in which storage cost and reliability are the objectives. Then, a genetic algorithm for solving the model is designed. Finally, experimental results indicate that the proposed model is positive and effective.

      • SCOPUSKCI등재

        Theoretical Study on Interactions between N-Butylpyridinium Nitrate and Thiophenic Compounds

        Lu, Renqing,Liu, Dong,Wang, Shutao,Lu, Yukun Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.6

        By using density functional theory calculations, we have performed a systemic study on the electronic structures and topological properties of interactions between N-butylpyridinium nitrate ($[BPY]^+[NO_3]^-$) and thiophene (TS), benzothiophene (BT), dibenzothiophene (DBT), naphthalene (NAP). The most stable structure of $[BPY]^+[NO_3]^-$ ion pair indicates that hydrogen bonding interactions between oxygen atoms on $[NO_3]^-$ anion and C2-H2 on pyridinium ring play a dominating role in the formation of ion pair. The occurrence of hydrogen bonding, ${\pi}{\cdots}$H-C, and ${\pi}{\cdots}{\pi}$ interactions between $[BPY]^+[NO_3]^-$ and TS, BT, DBT, NAP has been corroborated at the molecular level. But hydrogen bonding and ${\pi}{\cdots}{\pi}$ interactions between $[BPY]^+[NO_3]^-$ and NAP are weak in terms of structural properties and NBO, AIM analyses. DBT is prior to adsorption on N-butylpyridinium nitrate ionic liquid.

      • KCI등재

        Polymer gear contact fatigue reliability evaluation with small data set based on machine learning

        Liu Genshen,Wei Peitang,Chen Kerui,Liu Huaiju,Lu Zehua 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.2

        Polymer gears have shown potential in power transmission by their comprehensive mechanical properties. One of the significant concerns with expanding their applications is the deficiency of reliability evaluation methods considering small data set circumstances. This work conducts a fair number of polyoxymethylene (POM) gear durability tests with adjustable loading and lubrication conditions via a gear durability test rig. A novel machine learning-based reliability model is developed to evaluate contact fatigue reliability for the POM gears with such a data set. Results reveal that the model predicts reasonable POM gear contact fatigue curves of reliability–stress–number of cycles with 2.0% relative error and 18.8% reduction of test specimens compared with the large sample data case. In contrast to grease lubrication, the oil-lubricated POM gear contact fatigue strength improves by 10.4% from 52.1 to 57.6 MPa.

      • KCI등재

        Highly aligned indium zinc oxide nanowire-based artificial synapses with low-energy consumption

        Lu Liu,Binbin Cui,Wenlong Xu,Yao Ni,Shuo Zhang,Wentao Xu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.88 No.-

        Emulating neural activities at individual synapse level has recently attracted tremendous attention. Here,we demonstrate design and fabrication of thefirst digitally aligned nanowire (NW)-based three-terminalsynaptic transistor. The highly-aligned and individually-position-controlled long continuous indium zincoxide (IZO) NW arrays were directly printed on a large area with low cost using a specialelectrohydrodynamic nanowire printing (e-NWP) process. The NWs printed by e-NWP with a diameterof 250 nm emulated the structure of nervefibers. The device emulates plasticity of biological synapsesand showed remarkable advantages in energy consumption compared with previous reports. Uniqueband-edge modulation along the NW axial direction underlies makes excellent electrical properties ofthe device. This approach paves the way to easy fabrication of printed-NW-based artificial neuralnetworks.

      • Time Trends of Esophageal Cancer Mortality in Linzhou City During the Period 1988-2010 and a Bayesian Approach Projection for 2020

        Liu, Shu-Zheng,Zhang, Fang,Quan, Pei-Liang,Lu, Jian-Bang,Liu, Zhi-Cai,Sun, Xi-Bin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

        In recent decades, decreasing trends in esophageal cancer mortality have been observed across China. We here describe esophageal cancer mortality trends in Linzhou city, a high-incidence region of esophageal cancer in China, during 1988-2010 and make a esophageal cancer mortality projection in the period 2011-2020 using a Bayesian approach. Age standardized mortality rates were estimated by direct standardization to the World population structure in 1985. A Bayesian age-period-cohort (BAPC) analysis was carried out in order to investigate the effect of the age, period and birth cohort on esophageal cancer mortality in Linzhou during 1988-2010 and to estimate future trends for the period 2011-2020. Age-adjusted rates for men and women decreased from 1988 to 2005 and changed little thereafter. Risk increased from 30 years of age until the very elderly. Period effects showed little variation in risk throughout 1988-2010. In contrast, a cohort effect showed risk decreased greatly in later cohorts. Forecasting, based on BAPC modeling, resulted in a increasing burden of mortality and a decreasing age standardized mortality rate of esophageal cancer in Linzhou city. The decrease of esophageal cancer mortality risk since the 1930 cohort could be attributable to the improvements of socialeconomic environment and lifestyle. The standardized mortality rates of esophageal cancer should decrease continually. The effect of aging on the population could explain the increase in esophageal mortality projected for 2020.

      • KCI등재

        Coprime Representations and Feedback Stabilization of Discrete Time-varying Linear Systems

        Liu Liu,Yufeng Lu 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.2

        Within the framework of nest algebra, this paper deals with the stabilization problems of causal, discretetime, time-varying linear systems based on the coprime representations. It is shown that a linear system is stabilizableif and only if it admits a left coprime representation or a right coprime representation. The parametrizationof stabilizing controllers, strong stabilizability and simultaneous stabilizability criteria are characterized in terms ofleft coprime representations alone, or analogously right coprime representations alone.

      • KCI등재SCISCIE

        HtrA2 interacts with A beta peptide but does not directly alter its production or degradation.

        Liu, Meng-Lu,Liu, Ming-Jie,Kim, Jin-Man,Kim, Hyeon-Jin,Kim, Jeong-Hak,Hong, Seong-Tshool Korean Society for Molecular Biology 2005 Molecules and cells Vol.20 No.1

        <P>HtrA2/Omi is a mammalian mitochondrial serine protease homologous to the E. coli HtrA/DegP gene products. Recently, HtrA2/Omi was found to have a dual role in mammalian cells, acting as an apoptosis-inducing protein and being involved in maintenance of mitochondrial homeostasis. By screening a human brain cDNA library with A beta peptide as bait in a yeast two-hybrid system, we identified HtrA2/Omi as a binding partner of A beta peptide. The interaction between A beta peptide and HtrA2/Omi was confirmed by an immunoblot binding assay. The possible involvement of HtrA2/Omi in A beta peptide metabolism was investigated. In vitro peptide cleavage assays showed that HtrA2/Omi did not directly promote the production of A beta peptide at the beta/gamma-secretase level, or the degradation of A beta peptide. However, overexpression of HtrA2/Omi in K269 cells decreased the production of A beta40 and A beta42 by up to 30%. These results rule out the involvement of HtrA2/Omi in the etiology of Alzheimer's disease. However, the fact that overexpression of HtrA2/Omi reduces the generation of A beta40 and A beta42 suggests that it may play some positive role in mammalian cells.</P>

      • KCI등재

        A Review of Industrial MIMO Decoupling Control

        Lu Liu,Siyuan Tian,Dingyu Xue,Tao Zhang,YangQuan Chen,Shuo Zhang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.5

        In recent decades, MIMO (Multi-Input-Multi-Output) systems become more and more widely used inindustrial applications. A variety of decoupling control algorithms have been studied in the literature. Therefore,a review of the most extensively applied coupling interaction analysis and decoupler design methods for industrialprocesses is necessary to be carried out. In this paper, in order to benefit researchers and engineers with differentacademic backgrounds, the scattered coupling interaction analysis and decoupling algorithms are collectedand divided into different categories with their characteristics, application domains and informative comments forselection. Moveover, some frequently concerned problems of decoupling control are also discussed.

      • Conceptual design and optimization of polymer gear system for low-thrust turbofan aeroengine accessory transmission

        Lu Zehua,Liu Chang,Liao Changjun,Zhu Jiazan,Liu Huaiju,CHENYIMING 한국CDE학회 2024 Journal of computational design and engineering Vol.11 No.1

        The advancement in materials and lubrication has significantly improved the load-carrying capability of polymer gears, making them ideal for replacing metallic gears in power transmission. However, this conversion is not as simple as substituting steel with polymer; it requires a thorough redesign of the structural parameters specific to polymer gears. To enable the metallic-to-polymer conversion of gear in power transmission, a model for optimizing polymer gear systems was developed. An investigation of the accessory transmission system of a low-thrust turbofan aeroengine was conducted. A comprehensive performance index for the accessory transmission was developed using combined weighting coefficients to achieve the optimization goals including total mass, transmission efficiency, maximum transmission error, and so on. The polymer gear system developed using the proposed optimization model demonstrated a 70.4% reduction in total mass compared with the metallic gear system, as well as a transmission error decrease of over 29% when compared with polymer gear systems with standard tooth profiles. The contribution analysis results demonstrated that optimizing the tooth width, pressure angle, and addendum height of polymer gears can significantly enhance the load-carrying capacity of the polymer gear system while maximizing tooth profile flexibility.

      • Adjuvant Radiotherapy after Breast Conserving Treatment for Breast Cancer:A Dosimetric Comparison between Volumetric Modulated Arc Therapy and Intensity Modulated Radiotherapy

        Liu, Zhe-Ming,Ge, Xiao-Lin,Chen, Jia-Yan,Wang, Pei-Pei,Zhang, Chi,Yang, Xi,Zhu, Hong-Cheng,Liu, Jia,Qin, Qin,Xu, Li-Ping,Lu, Jing,Zhan, Liang-Liang,Cheng, Hong-Yan,Sun, Xin-Chen Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

        Background: Radiotherapy is an important treatment of choice for breast cancer patients after breast-conserving surgery, and we compare the feasibility of using dual arc volumetric modulated arc therapy (VMAT2), single arc volumetric modulated arc therapy (VMAT1) and Multi-beam Intensity Modulated Radiotherapy (M-IMRT) on patients after breast-conserving surgery. Materials and Methods: Thirty patients with breast cancer (half right-sided and half left-sided) treated by conservative lumpectomy and requiring whole breast radiotherapy with tumor bed boost were planned with three different radiotherapy techniques: 1) VMAT1; 2) VMAT2; 3) M-IMRT. The distributions for the planning target volume (PTV) and organs at risk (OARs) were compared. Dosimetries for all the techniques were compared. Results: All three techniques satisfied the dose constraint well. VMAT2 showed no obvious difference in the homogeneity index (HI) and conformity index (CI) of the PTV with respect to M-IMRT and VMAT1. VMAT2 clearly improved the treatment efficiency and can also decrease the mean dose and V5Gy of the contralateral lung. The mean dose and maximum dose of the spinal cord and contralateral breast were lower for VMAT2 than the other two techniques. The very low dose distribution (V1Gy) of the contralateral breast also showed great reduction in VMAT2 compared with the other two techniques. For the ipsilateral lung of right-sided breast cancer, the mean dose was decreased significantly in VMAT2 compared with VMAT1 and M-IMRT. The V20Gy and V30Gy of the ipsilateral lung of the left-sided breast cancer for VMAT2 showed obvious reduction compared with the other two techniques. The heart statistics of VMAT2 also decreased considerably compared to VMAT1 and M-IMRT. Conclusions: Compared to the other two techniques, the dual arc volumetric modulated arc therapy technique reduced radiation dose exposure to the organs at risk and maintained a reasonable target dose distribution.

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