http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Lifeng Cui,Qiulin Zhang,Chaochuang Yin,Shifei Kang,Zhigang Ge,Qineng Xia,Yangang Wang,Xi Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3
Water pollution caused by intensive use of organic dyes has become an increasingly serious problem recently. Green and efficient processes are desperately needed to remove persistent organic pollutants from waste waters. Herein, Ag nanoparticles loaded ZnO hollow microspheres were synthesized through a simple solvothermal method and used as a photocatalyst for dye degradation. The calculated band gap of Ag/ZnO — 5% (2.97 eV) is much narrower than that of pure ZnO (3.37 eV). The obtained Ag/ZnO samples show a remarkable photocatalytic activity in photodegradation of Rhodamine B (RhB) under simulated sunlight irradiation. The degradation efficiency of RhB for Ag/ZnO — 5% is 98.8% after 100 min irradiation while only 52.8% degradation rate is obtained over pure ZnO. The enhancement is attributed to the exposed active ZnO (001) plane and the surface plasmon resonance (SPR) effect of Ag nanoparticles that promote the separation of photogeneated electrons and holes.
Manganese induces neuroinflammation via NF-κB/ROS NLRP3 pathway in rat brain striatum and HAPI cells
Xinyuan Zhao,Lifeng Yin,Yifan Wu,Muxi Han,Yin Zhuang,Yewen Cong,Yiming Liu,Gang Chen,Junkang Jiang 대한독성 유전단백체 학회 2019 Molecular & cellular toxicology Vol.15 No.2
Backgrounds: Chronic exposure to excessive Mn can result in neurodegenerative symptoms, whose precise molecular mechanism remains largely unclear. Here, we measured the role and mechanism of NLRP3 in Mninduced neuroinflammation in vivo and vitro. Methods: The effects of Mn on NLRP3 activation were investigated by Westernblot, IHC, immunofluorescence analysis, as well as ELISA. We assessed NF-κB activation through measurement of phosphorylation and nuclear translocation. The mechanisms bywhich Mn induced NLRP3 activation were assessed by specific inhibitors. Results: We found that Mn exposure facilitated the activation of NLRP3 inflammasome to promote the production of IL-1β and IL-18 in dose- and time-dependent manners in HAPI cells. In addition, the NLRP3 inflammasome was also dramatically activated in microglia of rat brain striatum after Mn exposure. We also found increased ROS and NF-κB activation. Notably, the activation of NLRP3 was significantly attenuated by pretreatment with NF-κB and ROS inhibitors. Conclusion: These findings suggest that NLRP3 activation plays an important role in Mn-induced neuroinflammation, and it is associated with NF-κB and ROS.
Fengjie Cui,Zhiqiang Liu,Yin Li,Lifeng Ping,Liying Ping,Zhicai Zhang,Lin Lin,Ying Dong,Daming Huang 한국생물공학회 2010 Biotechnology and Bioprocess Engineering Vol.15 No.2
The Doehlert experimental design was used to optimize the production of mycelial biomass and exopolymer from Hericium erinaceus CZ-2 in this study. Statistical analysis showed that the linear and quadric terms of 3 variables: corn flour, yeast extract, and corn steep liquor had significant effects. The optimized combination of these 3 variables was confirmed through validation experiments. The optimal conditions for higher production of mycelial biomass (19.92 g/L) were estimated when the media composition concentrations were set as: 30.85 g/L,corn flour; 2.81 g/L, yeast extract; 16.9 mL/L, corn steep liquor; 10 g/L, glucose; 1 g/L, KH2PO4; and 0.5 g/L,MgSO4·7H2O; while a maximal exo-polymer yield (1.653g/L) could be achieved when setting concentrations of:32.71 g/L, corn flour; 2.35 g/L, Yeast extract; 14.42 mL/L,Corn steep liquor; 10 g/L, glucose; 1 g/L, KH2PO4; and 0.5g/L, MgSO4·7H2O. The upscale production was also investigated using a 15 L fermentor using the optimized medium.