消火器疾患과 蛋白同化 Steroid療法

高侊道 중앙대부설한국의과학연구소 1970 한국의과학 Vol.2 No.4

肝生檢法(Biopsy of the Liver)에 依한 輕度 肝腫大例의 組織像과 臨床像과의 比較硏究 : 第3編 肝吸蟲卵을 證明하는 輕度 肝腫大例에 關한 硏究 Studies on mild cases of clonorchiasis with slightly enlarged liver which were confirmed by fecal examination

高侊道 의약계사 1957 의약계 Vol.2 No.2

韓國과 日本과의 早期 胃癌의 比較

高侊道 고려대학교 의과대학 1981 고려대 의대 잡지 Vol.18 No.2

In this report, a comparative study was made on the early gastric cancer in Korea and Japan with respect to the age of patients and the type, depth of invasion and metastasis to lymphnodes. The data of 161 cases of the early gastric canner were all from the reports published in Korea, and the data in Japan were from the noes by Tasaka, Hayashida and Honda. This comparative study showed no difference except for a few respects. In regard to the age disiribution, there were higher frequency of the disease in the forth decade, and lower in the seventh decade in Korea than in Japan. As to their type, Ⅰ, Ⅱa, abd Ⅱb were less frequently discovered, while type Ⅲ was more frequently seen in Korea than in Japan. The case with a lesion lager than 3㎝ in the longest diameter was frequently observed in Korea in Japan. The incidence of the early gastric cancer was 6.5 per cent among 1,910 cases of resected gastric cancer in Korea, which was slightly lower compaired with that of the report by Honda.

Alcohol과 肝疾患

高侊道 大韓法醫學會 1979 대한법의학회지 Vol.3 No.1

Various complex factors including individual variations, sorts of alcoholic beverages, bodily state and manners on drinking as well as material other than alcohol contained in beverages, and quantity and quality of diet play roles in drinking phenomena. Therefore, chronic alcoholic intoxicants have intricate problems. The preceding lesions or conditions not only of the liver but of various organs could exert much influence on the liver. And so the discussions concerning the features of liver damage induced only by alcohol are very hard to make. In this study, acute alcoholic hepatitis and chronic alcoholic liver damage (fatty liver and liver cirrhosis) which can be produced chiefly by a large amount of drinking over a long period have been selected from a common sense standpoint. However, in this country, at present time, in the patients with chronic liver damage due to viral hepatitis, it is likely that there have been many mixed types to which hepatic damage due to drinking are supposed to add. There are cases of drinking too much for a long time in which the liver diseases are entirely absent while the liver diseases such as fatty liver and fatty liver cirrhosis are noted in a few cases of not drinking at all. From the above discussions, the fact that liver damage due to alcohol can be determined by whether dietary factors or constitutional factors is to be a subject of further discussion Furthermore, the discussions referring to the problems the liver damage by alcohol is whether primary or secondary due to the effects from other organs are thought to be necessary in future.

胃腸疾患의 食事療法

高侊道 대한의학협회 1975 대한의학협회지 Vol.18 No.4

Virus性 肝炎의 臨床症狀

高侊道 대한의학협회 1973 대한의학협회지 Vol.16 No.12

肝疾患의 Immunoglobulin量 變動에 관한 臨床的 硏究

金宗克,高侊道 고려대학교 의과대학 1975 고려대 의대 잡지 Vol.12 No.1

Author has studied 62 subjects who had been admitted to the Department of Gastroenterology, Medical College of Korea University and diagnosed by liver biopsy and 10 healthy Koreans from July, 1972 to Sept., 1973. Blood collected from the patients had been stored in freezing at -20 degree centigrade. The results of this study are as follows. 1. Blood level of immunoglobulins (Mean±Standard Deviation) in healthy Koreans are: IgG 1,387±254, IgA 171±78, IgM 94±33. The unit is ㎎/dl. 2. In acute hepatitis including icteric and nonicteric cases IgG is 1,616±314 and increased above normal range in 50 per cent of cases by mild degree with statistical significance. IgA is 313±86 and increased in 63 per cent by high degree with statistical significance and IgM is 133±66 and increased in 44 per cent by moderate degree with statistical significance. 3. In chronic hepatitis IgG is 1,788±302 and increased above normal range in 64 per cent of cases by mild degree with statistical significance. IgA is 347±127 and increased in 73 per cent by high degree with statistical significance. IgM is 143±80 and increased in 45 per cent by moderate degree without statistical significance. 4. In liver cirrhosis IgG is 1,958±449 and increased above normal range in 78 per cent by moderate degree with statistical significance. IgA is 390±129 and increased in 83 per cent by high degree with statistical significance. IgM is 160±69 and increased in 72 per cent by high degree with statistical significance. 5. In primary hepatoma IgG is 1,649±402 and increased above normal range in 71 per cent by mild degree without statistical significance. IgA is 376±171 and increased in 71 per cent by high degree with statistical significance. IgM is 149±66 and increased in 57 per cent by mild degree without statistical significance. 6. In reactive hepatitis IgG is 1,571±383 and increased above normal range in 40 per cent by mild degree without statistical significance. IgA is 333±130 and increased in 80 per cent by high degree with statistical significance. IgM is 123±62 and increased in 40 per cent by mild degree without statistical significance.

內視鏡的 胃粘膜像과 貧血에 關한 臨床的 硏究

金丞鎭,高侊道 고려대학교 의과대학 1973 고려대 의대 잡지 Vol.10 No.1

I performed the endoscopic examinations to 78 cases of anemia without hemorrhagic disorders in the G-I??tract among the admitted cases and O.P.D ones who had been treated in this hospital and observed their relation with the endoscopic gastric lesions following results were obtained. Distribution of anemia cases: Iron-deficiency anemia was 56 cases, aplastic anemia 6, chronic myelocytic leukemia 3, myxedema 2 and chronic hepatitis 11. The appearance of gastric mucosa of anemia cases surveyed by endoscopic examination: Visible mucous patterns are most frequently observed in 43.7%, vascular transparency in 32%, thinning patterns in 26.9%, granular in 26.9%, hemorrrhagic in 17.9% and pale in 16.7%. The findings obtained by endoscopic diagnosis: Normal gastric mucosa was 30.8%, atrophic gastritis 29.5% and hypertrophic gastritis 1.3%. The hemorrhagic pictures of gastric mucosa, subcutaneous hemorrhage and prolonged bleeding time: Anemia cases parallel with the prolonged bleeding time intimately. However, subcutaneous hemorrhage is not remarkable. The relationships between endosopic diagnosis and hemoglobin concentration in the anemia cases: There is a tendency that the cases of normal gastric mucosa are decreased in the cases of lower hemoglobin concentration. And the most cases of chronic gastritis are contained in the hemoglobin concentration of 7.1 to 10.9g/㎗ The relationships with gastric acid secretion: Achlorhydria is noted in 6.2% of cases of the normal gastric mucosa while 35.3% of cases of the chronic gastritis. As shown above, it suggests that the heterogenous organic pathologic lesions with main accompaniment of atrophic gastritis are not uncommon in the gastric lesions of anemia cases.

肝炎患者에 있어서 免疫 globulin 量과 肝機能檢査 所見에 관한 硏究

金文洙,高侊道 고려대학교 의과대학 1975 고려대 의대 잡지 Vol.12 No.3

The immunoglobulins(IgG, IgA and IgM) have been estimated in 26 cases of acute viral hepatitis and 22 cases of chronic hepatitis who had been admitted to this clinic by means of agar immunodiffusion method and the correlation with liver function test was observed which had been performed at the same time. All of the cases were confirmed by liver biopsy and other clinical patterns. The correlation was determined by probability acquired with Fisher's table after the correlation coefficient had been calculated statistically. The following results were obtained in this report. 1. In acute viral hepatitis the slope is negative between the value of IgG, serum albumin and to a certain degree and remarkably positive among total globulin, gamma globulin, S.G.O.T. and T.T.T. In chronic hepatitis the slope is positive only among the value of IgG, serum albumin and T.T.T. and remarkably negative between the value of IgG and S.G.P.T. 2. The value of IgA shows the remarkable positive slope with gamma globulin, total bilirubin, alkaline phosphatase, S.G.O.T. and T.T.T. However, all of the cases of chronic hepatitis have no correlation. 3. In acute viral hepatitis the positive slope is observed among the value of IgM and total globulin, gamma globulin and T.T.T. In chronic hepatitis albumin, total globulin and gamma globulin shows positive slope but negative with total bilirubin, S.G.O. and S.G.P.T. 4. No significant correlation coefficient is noted between the value of immunoglobulins(IgG, IgA, and IgM) and absolute lymphocyte count in acute viral hepatitis and chronic hepatitis.

內視鏡에 依한 慢性萎縮性胃炎의 臨床的 硏究

曺相圭,高侊道 고려대학교 의과대학 1973 고려대 의대 잡지 Vol.10 No.1

On performing the diagnosis of chronic gastritis the endoscopic examination is usually more useful than X-ray fluoroscopy. There have been many discussions concerning the classifications and etiologies about the chronic gastritis since Schindler. However, the clear -cut pattern of gastritis still has not been distinct as long as such discussions are concerned. In the face of these points of view, in this report, I studied 172 cases of subjects with primary chronic atrophic gastritis by means of endoscopic examinations such as gastrocamera or gastrofiberscope. Those results are as follows: On the age and sex distributions, 72.7 percent of all the cases are contained in the range of 40 to 59 years of age and the increase of incidence keeps pace with the older age groups. There is a tendency that male (62.2%) is more frequently invaded than female (37.8%), 40 percent of cases have the duration of 5 to 10 years and the majority of cases have the clinical courses of long duration with progression and remission. On the clinical symptoms, abdominal pain is complained of in 90.1 percent of all the cases and the nature of pain is not periodic 80.7% and dull ache 56.2%, The locations are distributed at the lower substernal areas in 60 percent of cases. In the relationships to meal, postprandial pain is complained of in 69.8 percent of cases. Of the other complaints, abdominal fullness are 57.6 percents, insomnia 52.3 percent, general fatiguability 48.8 percent and anorexia 68.6 percent. On the favorites, smoking is observed in 79.1 percent of all the cases but cases without alcohol or drinking coffee are noted in 57.6 percent and 71.5 percent each. The subjects would take slight red pepper diet in 35.5 percent. On the laboratory tests, gastric analysis, are revealed that hypoacidity is 52.9 percent and achlorhydria is 12.2 percent each. By X-ray examinations, normal results are obtained in 74.5 percent and in 16.8 percent of cases the results are same as ones by endoscopic findings. On the clinical course, the involved atrophic gastric mucosa in hardly thought to be recorvered to the normal states.