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孔福哲,金瑩均 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-
ASARI HERBA CUM RADICE was classified first-class herb by Shinnongbonchokyung(神農本草經) which was written in Chin-Han dynasty(秦漢代). It has been widely used to many diseases connected with nose, lung and cold evils. It can be gathered in many countries in Korea and China, and due to the reason many forgeries were soiled by herb merchant to medical doctors. This study was done in order to assist doctors using ASARI HERBA CUM RADICE more accurately. In small dose ASARI HERBA CUM RADICE has no toxic effect, but if used in large amount of ASARI HERBA CUM RADICE, it can produce many toxic effects. And doctors in past knew it already, so they alarmed it. And in order to exhibit more effects of ASARI HERBA CUM RADICE, it must be used only with root. The origins, shapes and effects of ASARI HERBA CUM RADICE were briefed in many cases, but those were not enough for effective use, so furthur studies ye to be followed in future.
정동균,이종흔,김각균,이공훈,오귀옥,정태영 대한구강생물학회 1980 International Journal of Oral Biology Vol.4 No.1
Those studies were performed to elucidate the effects of several dietary spices on dental caries and to determine which component of spices induced the change of incidence of dental caries in Sprague-Dawley rats which were supplied from SNU animal house. For this study, 132 rats (rats weighing 90-140 gm) were chosen at random with the same number of both sexes and divided into eleven experimental groups which contained the differential components of drinking water and diets for control and experimental group. Control group was fed standard cariogenic diet and tap water. In experimental groups, rats were fed standard cariogenic diet supplemented with capsicum (10%), ash capsicum (1, 10%), garlic (5%), common salt (3%), and analytical salt (3%) for 80 days. Drinking water was tap water containing water extract of capsicum (1, 10%), water extract of garlic (1.1%), and fluoride (50ppm). The results were as follows. 1. 54.6 in caries score was recorded in control group. 2. Rats which drank water containing 50ppm of fluoride showed 18.4% decrease in caries score. 3. Capsicum-fed rats showed 10.7% (capsicum 10%) increase in caries score and rats which drank water containing water extract of capsicum (1, 10%) showed 14.1% (w.e. capsicum 1%) and 0.16% (w.e. capsicum 10%) increase in caries score. But ash capsicum-fed rats showed 18.7% (ash capsicum 1%) and 7.3% (ash capsicum 10%) decrease in caries score. 4. Garlic-fed rats showed 22.1% (garlic 5%) decrease in caries score. But rats which drank water containing 1.1% of water extract of garlic showed 24.1% increase in caries score. 5. 58.4% and 68.0% increase in caries score were recorded in rats which were fed diet containing common salt (3%) and analytical NaCl (3%), respectively.
이종흔,정동균,정태영,김각균,민병무,이공훈 대한구강생물학회 1980 International Journal of Oral Biology Vol.4 No.1
This experiment was performed to elucidate the reported anti-cariogenic effect of capsicum in rats. Streptococcus mutans strain B-13, which was drived from human oral cavity and known to be cariogenic, was cultured in TYG with water-extract of capsicum. Glucose content of water-extract of capsicum was also determined by glucose oxidase method. The results are as follows. 1. Glucose content of water-extract of capsicum was 25.6 (±0.5) %. 2. In logarithmic phase, water-extract of capsicum group showed less steepness in growth curve than control group. 3. In early stationary phase, size of bacterial cell mass was in order of control, 0.5% and 1% water-extract of capsicum group. 4. It appears that water-extract capsicum might contain inhibitory substance to growth of Streptococcus mutans B-13, in spite of its high glucose content.
Ambiguity-free Doppler centroid estimation technique for airborne SAR using the Radon transform
Kong, Young-Kyun,Cho, Byung-Lae,Kim, Young-Soo IEEE 2005 IEEE transactions on geoscience and remote sensing Vol.43 No.4
In synthetic aperture radar (SAR) signal processing, the Doppler centroid estimation technique, called the 'clutter-lock', is important because it is related to the signal-to-noise ratio, geometric distortion, and radiometric error of the final SAR image. Conventional algorithms have either ambiguity problems or somewhat high computational load. Using the fact that the Doppler centroid and the squint angle are directly related, we propose an ambiguity-free Doppler centroid estimation technique using Radon transform, named geometry-based Doppler estimator. The proposed algorithm is computationally efficient and shows good performance of estimating the absolute Doppler centroid.
공영균(Kong Young Kyun),고보연(Ko Bo Yeon),정재훈(Jeong Jae Hoon) 대한전자공학회 2010 대한전자공학회 학술대회 Vol.2010 No.10
감시정찰용 SAR(Synthetic Aperture Radar)는 실시간 처리가 매우 중요하다. 항공탑재용으로 사용되는 SAR 시스템에서 SAR 데이터의 실시간처리하기 위해서는 보통 분산처리를 수행하며, 이를 위해서는 데이터/알고리즘 분할 방법 및 데이터 전송 구조의 설계의 최적화된 설계를 수행하여야 한다. 본 논문에서는 실시간처리를 위하여 다중 CPU를 사용한 병렬 SAR신호 처리 소프트웨어의 설계 결과 및 처리 결과를 보였고 성능을 평가하였다.
( Young Eun Chon ),( Han Ah Lee ),( Jun Sik Yoon ),( Jun Yong Park ),( Bo Hyun Kim ),( In Joon Lee ),( Suk Kyun Hong ),( Dong Hyeon Lee ),( Hyun-joo Kong ),( Young-joo Won ),( Eunyang Kim ),( Jeong-ho 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Considering the high prevalence and the mortality of hepatocellular carcinoma (HCC) in Korea, accurate statistics for HCC is important. We evaluated the characteristics of newly diagnosed Korean HCC patients between 2012 and 2014. Methods: Data from The Korean Primary Liver Cancer Registry (KPLCR) which consists of approximately 15% random sample of entire HCC patients in the Korean Central Cancer Registry were utilized. Baseline characteristics, treatment modalities, and overall survival (OS) of 4,572 patients with HCC registered in the KPLCR between 2012 and 2014 have been investigated. Results: At the time of HCC diagnosis, mean age was 60.0±10.8 years, with male predominance (79.6%). Hepatitis B virus was the predominant etiology (59.1%). The Barcelona Clinic Liver Cancer (BCLC) stages at diagnosis were 3.9%, 36.9%, 12.5%, 39.4% and 7.3% for BCLC stage 0, A, B, C, and D, respectively. The proportion of HCC diagnosed at BCLC stage 0 or A between 2012 and 2014 were significantly lower compared to that between 2008 and 2011 (40.8% vs. 48.3%, P<0.001). Transarterial therapy (37.5%) was the most commonly performed initial treatment, followed by surgical resection (19.8%), best supportive care (19.1%), and local ablation therapies (10.6%). The median survival was 2.9 years, and the 1-, 3-, and 5-year OS rates were 67.7%, 49.3% and 41.9%, respectively. The OS of HCC patients between 2012 and 2014 was significantly longer than that of patients between 2008 and 2011 (log-rank test, P<0.001). Conclusions: About half of the patients (46.7%) were diagnosed at advanced HCC (BCLC stage C or D). Although large proportion of HCC patients between 2012 and 2014 were diagnosed at advanced stages, the OS has been improved which warrants further analysis.
孔福哲,金塋均 대한한방성인병학회 1998 韓方成人病學會誌 Vol.4 No.1
This study was investigated the inhibitory activity of RADIX ASARI (RA) on type Ⅰ immediate hypersensitivity of the anaphylactic type. RA inhibited compound 48/80 -induced anaphylaxis 100% with a dose of 0.5g/㎏ body weight at 1 h before or 5 and 10 min after injection of compound 48/80. RA also exhibited the dose-dependent inhibitory effect on compound 48/80-induced, substance-p-induced and anti-DNP IgE-induced histamine release from rat peritoneal mast cells. Moreover, it was clearly demonstrated that RA and disodium cromoglycate disodium cromoglycate potently inhibited such type Ⅰ allergic reactions as anaphylactic shocks, suggesting that these drugs, at least in part, share the same mechanism of action. It is suggested that RA may exert a stronger inhibition on the mast cell degranulation process. When I examined the effect of RA on the release of IgE in the mouse spleen whole cells and human myeloma U266131, the release of IgE is inhibited by RA. Stimulation of RBL-2H_3 cells with anti-DNP IgE for 16hr induced the expression of TNF-α mRNA but RA decreased TNF-α mRNA expression. These results suggest the possibility that RA-induced inhibition of type Ⅰ allergic reaction is regulated by histamine, IgE and TNF-α.
Production of Kittens from Non-Surgical Intrauterine Insemination of Frozen Epididymis Semen in Cat
Young-Ho Lee,Dae-Joong Yu,Hyo-Sang Lee,Youn-Gil Seo,Se-Sin Jeon,Su-Jin Cho,Young-Ho Kim,Xi-Jun Yin,Seong-Kyun Cho,In-Hyu Bae,Il-Keun Kong 한국동물생명공학회(구 한국동물번식학회) 2004 Reproductive & Developmental Biology(Supplement) Vol.28 No.2s
Determinants of the Socio-economic and Emotional Status of the Elderly in Korea
Kong-Kyun Ro(노공균),So-Young Cho(조소영),Dong-Sook Shin(신동숙),Tae-Hoon Lee(이태훈) 한국인구학회 1991 한국인구학 Vol.14 No.2
1. 問題點(Setting of Problems) 産業의 急進的인 進步는 高度의 技術社會(high-tech societies)를 創出해 내었고, 이로 인해 生産樣式뿐만 아니라, 價値體系 및 生活樣式이 急進的으로 變化하였다. 동시에, 産業化 및 生活水準의 向上은 人口統計學的 變遷(demographic transition)을 가져와, 人口의 老齡化가 이루어졌다. 産業化에 의해 發生된 이러한 現狀들 즉, 價値體系의 變化와 人口의 老齡化가 바로 問題의 核心인 것이다. 産業化는 效率(efficiency)에 높은 價値를 賦與함으로서, 精神的인 人間體系側面의 重要性을 無視하고, 老齡化란 多次元的(multi-dimensional) 問題를 일으켰다. 이러한 問題들의 解決策으로서 西歐的인 價値槪念은 老人들의 生活의 質(quality of life)을 向上시키지 못한 것으로 생각된다. 따라서, 物質的인 面 이외에 精神的인 面의 接近法을 必要로 하게 되는 것이다. 2. 硏究의 目的(Objective of the Study) 이 硏究의 目的은 韓國에 있어서의 人口의 老齡化의 原因과 結果에 대한 硏究를 하는데 있다. 이러한 硏究에 의해 老齡化라는 多次元的 問題에 대한 智識을 얻으므로써, 社會, 共同體 및 家族 水準에서의 老齡化 問題를 다루는데 있어 非西歐的 接近法 및 政策的 戰略에 관한 方案을 提示하게 되기를 希望한다. 3. 方法論(Methodology) 1) 資料 蒐集(Data Collection) 資料는 다음 세가지 源泉으로부터 얻어졌다. 첫째, 出版된 資料 및 會議書類 둘째, 韓國保健社會硏究院과의 協助로 行해진 說問紙 調査 셋째, 自體 硏究팀에 의해 行해진 面談 2) 資料分析(Data Analysis) 原因分析(cause - effect types of analyses)은 probit, logit, path analyses에 의해 行해졌다. 이 硏究論文에는 trend analysis의 結果는 提示되지 않았는데, 이는 多樣한 政府機關에 의해 出刊된 分析들과 類似하기 때문이다. 4. 硏究分析의 結果 첫째, 經濟的 要因은 老人들의 生活狀態를 決定하는데 가장 중요한 要因이라는 것을 알 수 있다. 둘째, 老人의 社會的인 統合이 ?할수록 보다 幸福한 生活을 營爲하는 것으로 나타났다. 셋째, 性(sex), 敎育程度, 住居地域 등의 老人의 雇傭狀態 및 所得水準과 큰 關係가 있다. 넷째, 敎育程度, 社會的 統合(social integration) 등이 健康狀態와 密接한 關係가 있다. 다섯째, 社會的 統合, 健康狀態, 獨立心 등이 老人의 情緖的 狀態에 큰 影響을 미친다.