Variation in clinical usefulness of biomarkers of acute kidney injury in young children undergoing cardiac surgery

Baek, Hee Sun,Lee, Youngok,Jang, Hea Min,Cho, Joonyong,Hyun, Myung Chul,Kim, Yeo Hyang,Hwang, Su-Kyeong,Cho, Min Hyun The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.4

Background: Acute kidney injury (AKI) is one of the most significant postoperative complications of pediatric cardiac surgery. Because serum creatinine has limitations as a diagnostic marker of AKI, new biomarkers including neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and interleukin-18 (IL-18) are being evaluated to overcome these limitations and detect AKI at an early stage after cardiac surgery. Purpose: This study aimed to investigate the clinical usefulness of these biomarkers in young children. Methods: Thirty patients with congenital heart diseases who underwent cardiac surgery using cardiopulmonary bypass (CPB) were selected, and their urine and blood samples were collected at baseline and 6, 24, and 48 hours after surgery. Serum creatinine and blood urea nitrogen levels as well as NGAL, KIM-1, and IL-18 levels in urine samples were measured, and clinical parameters were evaluated. Results: Of the 30 patients, 12 developed AKI within 48 hours after cardiac surgery. In the AKI group, 8 of 12 (66.6%) met AKI criteria after 24 hours, and urine KIM-1/creatinine (Cr) level (with adjustment of urine creatinine) peaked at 24 hours with significant difference from baseline level. Additionally, urine KIM-1/Cr level in the AKI group was significantly higher than in the non-AKI group at 6 hours. However, urine NGAL/Cr and IL-18/Cr levels showed no specific trend with time for 48 hours after cardiac surgery. Conclusion: It is suggested that urine KIM-1/Cr concentration could be considered a good biomarker for early AKI prediction after open cardiac surgery using CPB in young children with congenital heart diseases.

Evaluation of BMI as an Obesity Index for Korean

Kim, Youngok,Lee, Soon-Young,Kim, Seon-Woo,Kim, Kyung-Hee 대한지역사회영양학회 2000 Journal of community nutrition Vol.2 No.2

The purpose of the present study is to evaluate the validity of the BMI as an indicator of obesity for Koreans. The usefulness of the BMI to represent overweight and obesity was evaluated by measuring the relative validity of sensitivity and specificity, and was compared with the validity of triceps skinfold thickness(mm). To measure the relative validity of the BMI and triceps skinfold thickness, body fat(%) was used as a reference measure of obesity. The study population included 844 participants aged 20-69 years who resided in Kuri City in Kyunggi province. Participants were measured regarding weight, height, triceps skinfold thickness and body fat. The prevalence of obesity for male subjects was 32.0%, 66.2%, and 0.9%, and for female subjects, 17.6%, 56.1%, 12.4% based on the BMI, triceps skinfold thickness, and body fat(%) respectively. The prevalence of obesity was higher based on the BMI or triceps skinfold thickness than body fat measurement. The sensitivity and specificity of the BMI were 33.3% and 67.9% in male subjects and 77.7% and 90.8% in female subjects. Sensitivity of the BMI was lower, and specificity was higher than those of triceps skinfold thickness. In summary, BMI as an indicator of obesity for Korean showed a tendency of overestimation of obesity prevalence. Therefore, there is a need to develop a more reliable obesity index other than the BMI for Koreans.

Caffeine이 지방세포주 3T3-L1 분화에 미치는 영향 : 영양유전체학적 접근

김미자(Kim Mi-Ja),김영옥(Kim Youngok),정주호(Chung Joo-Ho),김종우(Kim Jong-Woo),김혜경(Kim Hye-Kyung) 韓國營養學會 2005 Journal of Nutrition and Health Vol.38 No.8

Study on Motion Recognition Scheme Using Acceleration Sensor in Mobile Devices

Younghoon Kim,Sangyub Kim,Dongmin Kang,Hwangsoo Park,Nammoon Kim,Sung Hyun Yang,Youngok Kim 보안공학연구지원센터 2013 International Journal of Smart Home Vol.7 No.6

엘라스틱 스택에 기반한 실시간 웹서비스 관제 시스템의 설계와 구현

김종민(Jongmin Kim),김채윤(Chae Yoon Kim),김호준(HoJun Kim),Khin Chan Myae Aung,손미정(Mijeong Son),김영옥(YoungOk Kim),권오흠(Oh-Heum Kwon),송하주(Ha-Joo Song) 한국정보과학회 2018 한국정보과학회 학술발표논문집 Vol.2018 No.6

Structural Behavior of KSTAR CS Magnet During Plasma Operation

Ahn, Hee-Jae,Park, Hyun-Ki,Kim, Jinsub,Kim, YoungOk,Kim, Kwang Pyo,Chu, Yong,Kim, Hyun-Seok,Park, Kaprai,Oh, Yeong-Kook,Lee, Sudo,Kim, Yong Hwan Institute of Electrical and Electronics Engineers 2018 IEEE transactions on applied superconductivity Vol.28 No.3

<P>The finite element model of KSTAR central solenoid (CS) magnet has been developed with new smeared orthotropic material properties of CS coils and the effective coefficient of thermal expansion of the magnet structures. The accuracy of structural analysis for assembly and cool-down processes is higher than in previous studies. Electromagnetic analysis was performed to evaluate Lorentz forces of poloidal field (PF) coils during a long pulse discharge. The analyzed structural behavior of the CS magnet was clearly consistent with the measured data and calculated Electromagnetic (EM) forces during the plasma operation. The current of PF4 coil had a significant effect on axial compression and the minimum preloading was maintained at 2.0 MN in the end of plasma. Equivalent EM force can easily predict the axial compression of CS magnet without complicated structural analysis. The study on the structural behavior of CS magnet is expected to provide the optimal combination of PF coil current limits for large plasma current and long pulse discharges.</P>

Dietary Patterns and Health Behaviors of Hypertensive Korean Adults

Kim, Youngok,Lee, Soon-Young The Korean Society of Food Science and Nutrition 2002 Preventive Nutrition and Food Science Vol.7 No.2

Findings from European and American studies have indicated such health behaviors as smoking, drinking, lack of exercise, and insufficient intake of grains, fruits and vegetables as risk factors for hypertension. However, because dietary pattern and health behaviors of Korean differ from people of other countries, the risk factors for Koreans could be different. Therefore, the aim of this study was to identify food consumption patterns and health behavior characteristics of Korean hypertensive adults. Data on food consumptions and other health behaviors such as smoking, drinking, and exercise together with development of hypertension were collected from 597 persons aged 20 to 69 years in a local community. The first stage of analysis utilized cluster analysis to aggregate individuals into different health behavior and food consumption groups. Four health behavior groups were characterized by passive cluster, smoker cluster, fitness cluster and drinker cluster. Food consumption patterns of the subjects were also aggregated into 4 different clusters: dairy cluster, grain & vegetable cluster, fruit cluster, and fish & meat cluster. Then univariate analysis was followed to identify the variables associated with hypertension. The final stage of analysis was the identification of the relative importance of the variables selected from the univariate analysis on hypertension, using multiple logistic analysis. The results showed that heavy drinking was the most significant health behavior associated hypertension, which was similar to the findings in European and American studies. However, unlike the findings from foreign studies, grain and vegetable consumption appeared to be a risk factor for hypertension. A possible reason for the contradictory results between Korean and Western studies may be the dependence of Koreans on white rice as the major staple food, and/or the frequent consumption of salted vegetables, rather than fresh vegetables as is customary in Europe and America.

An Enhanced 3D Positioning Scheme Exploiting Adaptive Pulse Selection for Indoor LOS Environments

Kim, Youngok,Kim, Nammoon Springer-Verlag 2014 WIRELESS PERSONAL COMMUNICATIONS Vol.77 No.4

Changing Patterns of Diet in Korea

Kim, Youngok 中央醫學社 1991 中央醫學 Vol.56 No.12

1960년대이후 한국사회의 급격한 변하로 한국인의 질병 및 사망양상이 크게 변화해 가고있다. 사망원인의 연차적 변동을 보더라도 60년대 중반까지는 전염성질환이 주종을 이루던 것이 1970년대말에는 만성퇴행성질환에 의한 사망이 전체의 50%에 이르는 것을 볼 수 있다. 이러한 변화는 국민 식생활의 변화와도 무관하지 않을 뿐만아니라 이 기간동안에 일어난 국민식이섭취 유형의 변화는 질병양상의 변화를 이해하는데 도움이 된다. 이에 본 연구는 1960년대이후 25년간의 국민식생활의 변화추이를 두가지의 자료원을 이용하여 고찰하여 보았다. 그 하나는 식품구급표를 통해 나타나는 식품의 공급량이고 다른 하나는 국민영양조사보고서를 통해 나타난 식품 및 영양소의 섭취량이다. 이상의 자료를 이용하여 국민식생활 양상의 양적, 질적 변화를 관찰하였다. 우선 첫번째 단계로 년도별 식품공급량의 변화를 보았고, 두번째로는 이러한 공급량의 변화가 실지로 국민의 식품섭취량에 어떤 양상으로 반영되었느냐 하는 것이고, 세째로는 국민식생활의 질적변화를 영양소섭취 내용의 변화를 통해 관찰하였는데 전체섭취하는 열량중 탄수화물, 단백질, 지방의 기여도를 중심으로 관찰하였다. 관찰결과를 요약하면 감자를 제외한 모든 식품군의 공급량의 증가추세를 보였으며 가장 공급량이 크게 증가한 식품군은 우유와 유제품이었다. 곡류의 공급은 전 관찰기간을 통해 거의 변화없이 일정한 수준이었다. 다음으로 국민영양조사 보고서상 나타난 실질적인 섭취량은 공급량의 변화없이 일정한 수준이었다. 다음으로 국민영양조사 보고서상 나타난 실질적인 섭취량은 공급량의 변화와 거의 같은 유형을 보여주고 있다. 단 곡류와 채소의 경우는 공급량은 증가하였는데 실질적인 섭취량은 감소하는 것으로 간주어 식품공급의 추세가 반드시 섭취의 양상으로 그대로 나타나지 않는 것을 알 수 있었다. 전체열량 섭취중 탄수화물의 기여도는 25년 관찰기준중 81%에서 74%로 떨어졌고 지방의 기여도는 7%에서 12%로 증가했으나 단백질의 기여도는 거의 변화하지 않았다. 이상의 관찰결과는 요약하면 25년의 관찰기간중 식품의 공급과 섭취량이 점진적 증가를 보인 반면 단백질을 중심으로 본 식이의 질적변화는 극히 적었던 것으로 관찰되었다. 뿐만아니라 1980년대 전반까지도 칼슘, 비타민 A₁, 비타민 B₂의 섭취수준이 권량량에 미치지 못하는 수준이었다.

3D positioning scheme exploiting nano-scale IR-UWB orthogonal pulses

Kim, Nammoon,Kim, Youngok Springer 2011 NANOSCALE RESEARCH LETTERS Vol.6 No.1

<P>In these days, the development of positioning technology for realizing ubiquitous environments has become one of the most important issues. The Global Positioning System (GPS) is a well-known positioning scheme, but it is not suitable for positioning in in-door/building environments because it is difficult to maintain line-of-sight condition between satellites and a GPS receiver. To such problem, various positioning methods such as RFID, WLAN, ZigBee, and Bluetooth have been developed for indoor positioning scheme. However, the majority of positioning schemes are focused on the two-dimension positioning even though three-dimension (3D) positioning information is more useful especially in indoor applications, such as smart space, U-health service, context aware service, etc. In this paper, a 3D positioning system based on mutually orthogonal nano-scale impulse radio ultra-wideband (IR-UWB) signals and cross array antenna is proposed. The proposed scheme uses nano-scale IR-UWB signals providing fine time resolution and high-resolution multiple signal specification algorithm for the time-of-arrival and the angle-of-arrival estimation. The performance is evaluated over various IEEE 802.15.4a channel models, and simulation results show the effectiveness of proposed scheme.</P>