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      • SCIESCOPUSKCI등재

        Evaluation of dental panoramic radiographic findings in edentulous jaws: A retrospective study of 743 patients "Radiographic features in edentulous jaws"

        Kose, Taha Emre,Demirtas, Nihat,Karabas, Hulya Cakir,Ozcan, Ilknur The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.5

        PURPOSE. The aim of this study was to determine the frequency of significant panoramic radiographic findings and eventual treatment requirements before conventional or implant supported prosthetic treatment in asymptomatic edentulous patients. MATERIALS AND METHODS. A total of 743 asymptomatic edentulous patients were retrospectively evaluated using a digital panoramic system. We analyzed the radiographic findings, including impacted teeth, retained root fragments, foreign bodies, severe atrophy of the posterior maxillary alveolar bone, mucous retention cysts, soft tissue calcifications and radiopaque-radiolucent conditions. RESULTS. Four-hundred-eighty-seven (65.6%) patients had no radiographic finding. A total of 331 radiographic findings were detected in 256 (34%) patients. In 52.9% (n=175) of these conditions, surgical treatment was required before application of implant-supported fixed prosthesis. However, before application of conventional removable prosthesis surgical treatment was required for 6% (n=20) of these conditions. CONCLUSION. The edentulous patients who will have implant placement for implant-supported fixed prosthesis can frequently require additional surgical procedures to eliminate pathological conditions.

      • Could the Platelet-to-Lymphocyte Ratio be a Novel Marker for Predicting Invasiveness of Cervical Pathologies?

        Kose, Mesut,Celik, Fatih,Kose, Seda Kayman,Arioz, Dagistan Tolga,Yilmazer, Mehmet Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

        Purpose: To determine whether the preoperative platelet to lymphocyte ratio (PLR) could predict invasiveness of cervical pathologies. Materials and Methods: Patients with preinvasive and invasive diseases were reviewed retrospectively, over a nine-year period, 2005-2014. The pathological records and completed blood counts of the patients were collected and recorded in the SPSS program. Patients were divided in two groups, preinvasive and invasive. Results: The median PLR was significantly higher in the invasive group than in the preinvasive group (p=0.03). There was a correlation between invasion of cervical cancer and white blood cell count, red cell distributing width (RDW), neutrophil-lymphocyte ratio (NLR), and PLR. Conclusions: This study showed that patients with uterine cervical cancer may present with leukocytosis, increased RDW, NLR and PLR. These cheap and easily available parameters, especially PLR, may provide useful information about the invasiveness of cervical lesions.

      • Mothers' Knowledge and Attitudes about HPV Vaccination to Prevent Cervical Cancers

        Kose, Dilek,Erkorkmaz, Unal,Cinar, Nursan,Altinkaynak, Sevin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

        Background: Cervical cancer which is one of the most preventable cancers is an important public health problem worldwide, and especially in developing countries. The aim of this study was to determine knowledge and attitudes about the HPV vaccination of mothers with 0- to 18-year old children. Materials and Methods: Written approval was taken from the local authorities. The study subjects consisted of 799 mothers who agreed to participate. The data were collected via a "Personal Information Form" which included 30 questions that were prepared by the researchers themselves in line with the literature. The data were collected by face to face interviews with the mothers. Analyses were performed using commercial software. Results: The mean age of the mothers who participated in the study was $32.0{\pm}6.52$, and 88.1% reported no information about HPV, and 83.5% no information about HPV vaccination. Only 0.7% of the mothers had daughters who had HPV vaccination, and 44.3% of the mothers who had sons were found out to be indecisive about having HPV vaccination. There was a significant corelation between the educational status of the mothers and their knowledge about HPV vaccination (p<0.05). However, there was no significant correlation in terms of economic conditions (p>0.05). Conclusions: This study suggested that mothers had very little information on HPV and HPV vaccination. Knowledge of the disease and its vaccination is an essential factor for the success of the vaccination program. It is of great importance that mothers are trained in this subject by health professionals.

      • SCIESCOPUS

        Effects of infill walls on RC buildings under time history loading using genetic programming and neuro-fuzzy

        Kose, M. Metin,Kayadelen, Cafer Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.3

        In this study, the efficiency of adaptive neuro-fuzzy inference system (ANFIS) and genetic expression programming (GEP) in predicting the effects of infill walls on base reactions and roof drift of reinforced concrete frames were investigated. Current standards generally consider weight and fundamental period of structures in predicting base reactions and roof drift of structures by neglecting numbers of floors, bays, shear walls and infilled bays. Number of stories, number of bays in x and y directions, ratio of shear wall areas to the floor area, ratio of bays with infilled walls to total number bays and existence of open story were selected as parameters in GEP and ANFIS modeling. GEP and ANFIS have been widely used as alternative approaches to model complex systems. The effects of these parameters on base reactions and roof drift of RC frames were studied using 3D finite element method on 216 building models. Results obtained from 3D FEM models were used to in training and testing ANFIS and GEP models. In ANFIS and GEP models, number of floors, number of bays, ratio of shear walls and ratio of infilled bays were selected as input parameters, and base reactions and roof drifts were selected as output parameters. Results showed that the ANFIS and GEP models are capable of accurately predicting the base reactions and roof drifts of RC frames used in the training and testing phase of the study. The GEP model results better prediction compared to ANFIS model.

      • Biohydrogen production from engineered microalgae Chlamydomonas reinhardtii

        Kose, Ayse,Oncel, Suphi S. Techno-Press 2014 Advances in energy research Vol.2 No.1

        The green microalgae Chlamydomonas reinhardtti is well-known specie in the terms of $H_2$ production by photo fermentation and has been studying for a long time. Although the $H_2$ production yield is promising; there are some bottlenecks to enhance the yield and efficiency to focus on a well-designed, sustainable production and also scaling up for further studies. D1 protein of photosystem II (PSII) plays an important role in photosystem damage repair and related to $H_2$ production. Because Chlamydomonas is the model algae and the genetic basis is well-studied; metabolic engineering tools are intended to use for enhanced production. Mutations are focused on D1 protein which aims long-lasting hydrogen production by blocking the PSII repair system thus $O_2$ sensitive hydrogenases catalysis hydrogen production for a longer period of time under anaerobic and sulfur deprived conditions. Chlamydomonas CC124 as control strain and D1 mutant strains(D240, D239-40 and D240-41)are cultured photomixotrophically at $80{\mu}mol\;photons\;m^{-2}s^{-1}$, by two sides. Cells are grown in TAP medium as aerobic stage for culture growth; in logarithmic phase cells are transferred from aerobic to an anaerobic and sulfur deprived TAP- S medium and 12 mg/L initial chlorophyll content for $H_2$ production which is monitored by the water columns and later detected by Gas Chromatography. Total produced hydrogen was $82{\pm}10$, $180{\pm}20$, $196{\pm}20$, $290{\pm}30mL$ for CC124, D240, D239-40, D240-41, respectively. $H_2$ production rates for mutant strains was $1.3{\pm}0.5mL/L.h$ meanwhile CC124 showed 2-3 fold lower rate as $0.57{\pm}0.2mL/L.h$. Hydrogen production period was $5{\pm}2days$ for CC124 and mutants showed a longer production time for $9{\pm}2days$. It is seen from the results that $H_2$ productions for mutant strains have a significant effect in terms of productivity, yield and production time.

      • Competence in Healthcare Managers: HLA Model

        Aslı Kose Unal KINFORMS 2017 Management Review Vol.12 No.2

        In recent years, competencies in corporations have been used in the performance assessment process in the field of human resources. When competencies are accepted as observable behaviors including distinctive knowledge, skills and attitudes in achieving excellent performance. Performance is a concept that determines the outcome of an intentional and planned activity quantitatively or qualitatively. Competencies in assessing corporation and individual performance are key roles. In particular, the determination of the competencies of the managers adds positive value to the managers and to the corporation. It is an effective factor in achieving success and what the managers are aiming for health managers as well, like other managers, to be aware of their competencies. One of the models developed to assess the competencies of health care managers is the Healthcare Leadership Alliance (HLA). This article contains the model for assessment of the competences of the healthcare managers developed by the American College of Healthcare Executives and the studies conducted in this field.

      • KCI등재
      • KCI등재후보
      • SCOPUSKCI등재

        Quorum quenching for effective control of biofouling in membrane bioreactor: A comprehensive review of approaches, applications, and challenges

        Borte Kose-Mutlu,Tulay Ergon-Can,Ismail Koyuncu,Chung-Hak Lee 대한환경공학회 2019 Environmental Engineering Research Vol.24 No.4

        In comparison to alternative advanced wastewater treatment technologies, the main problem associated with membrane bioreactor (MBR) technology, which has become prominent in recent years, is biofouling. Within these systems, biofouling is typically the result of a biofilm layer resulting from bacterial gathering. One biological system that can be employed to interrupt the process of bacterial gathering is called ‘Quorum Quenching (QQ)’. Existing QQ applications can be classified using three main types: 1) bacterial/whole-cell applications, 2) direct enzyme applications, and 3) natural sourced compounds. The most common and widely recognized applications for membrane fouling control during MBR operation are bacterial and direct enzyme applications. The purpose of this review was to identify and assess biofilm formation mechanism and results, the suggestion of the QQ concept and its potential to control biofilm formation, and the means by which these QQ applications can be applied within the MBR and present QQ MBR studies.

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