Association between rosacea and systemic comorbidities: a matched case-control study using health check-up program data

( Junghwa Yang ),( Yunho Lee ),( Sunmin Yim ),( Jung Yup Kim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Han-saem Kim ),( Young Jun Choi ),( Jae-hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Rosacea is a chronic inflammatory skin disease with various clinical manifestations. Its cause and pathophysiology are not fully understood, but recently it has been shown to have an association with numerous systemic diseases. Objectives: To investigate (1) the association between rosacea and systemic comorbidities and (2) if the subtypes and the severity of rosacea have an effect on comorbidities. Methods: A matched case-control study was conducted using health care center data for three years (2014-2017). Rosacea group was identified by clinical photo review of two dermatologists. Rosacea-free control group was matched to case by age and sex. By using SPSS version 19.0., the data measured in health check-up program were analyzed. Results: Among 1829 subjects who visited our center, 229 (case) and 458 (control) were identified and selected for analysis. Body mass index(BMI), family history of liver disease and past medical history of thyroid cancer, hypertension, and kidney disease are associated with rosacea. Conclusion: Rosacea is associated with several systemic comorbid diseases.

Genetic diversity and population structure of the long-tailed goral, Naemorhedus caudatus, in South Korea.

Choi, Sung Kyoung,Chun, Suwon,An, Junghwa,Lee, Mu-Yeong,Kim, Hyeon Jeong,Min, Mi-Sook,Kwon, Soo-Wan,Choi, Tae Young,Lee, Hang,Kim, Kyung Seok Genetics Society of Japan 2015 Genes & genetic systems Vol.90 No.1

<P>The long-tailed goral, Naemorhedus caudatus, is an internationally endangered species. This species is distributed throughout Northeastern Asia including Northeastern China, the Russian Far East and the Korean peninsula. The population size of long-tailed gorals is currently decreasing in South Korea, and thus effective conservation of the animal is urgently needed. Although the evolution and phylogeny of this animal have been studied, population genetic studies are needed to design effective conservation and management strategies. To evaluate the present status of genetic diversity and genetic structure of long-tailed gorals in South Korea, we investigated genetic variability among 68 goral individuals from different regions, including 11 captive zoo animals, at 12 microsatellite loci. The level of genetic diversity was moderate in wild goral populations, but lower in the captive group. The goral population from the lower northeast region of South Korea was distinct from the upper northeast population, probably due to the natural climatic and geographic conditions. The genetic characteristics of the captive group were more similar to those of the upper northeast population than the lower northeast, confirming that the zoo animals originated in the Seorak Mountain range. Direct translocations between the upper and lower northeast populations are not currently recommended considering the natural population structure and the moderate levels of genetic diversity in the two populations. This study highlights the importance of genetic information in designing effective conservation strategies and translocations of endangered animals, including the Korean goral.</P>

A case of CD30+ T-cell lymphoproliferative disorder following trauma on the scalp

( Junghwa Yang ),( Yeon Gu Choi ),( Gyoo Huh ),( Hyeon Jeong Park ),( Yun Ho Lee ),( Sunmin Yim ),( Jung Yup Kim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

CD30+ lymphoproliferative disorders are the second most common primary cutaneous T-cell lymphoma, which include lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. Recently, CD30+ inflammatory reactions have been reported in a variety of infectious or inflammatory diseases, such as arthropod bites, herpes simplex infection, drug reactions, and atopic dermatitis. Among them, post-traumatic atypical CD30+ T-cell proliferation is an extremely rare case of these entities. It can mimic a cutaneous lymphoma, but clinical presentation or prognosis might quite different. It is important to distinguish these cases from other diseases. A 17-year-old male presented with a solitary 2 cm-sized nodule with yellowish discharge on the vertex. After bumping the scalp four days ago, there was a sore lump that increased in size. He denied other constitutional symptoms except for those associated with skin lesion. On the basis of histopathologic examination, large collected atypical vesicular lymphoid cells and geographic necrosis were observed under the ulcerative epidermis. In immunohistochemical analysis, tumor cells were positive for CD43, CD45, CD4, CD3, CD5, and CD30. The lesion was treated with surgical excision and the postoperative site has been stable without any recurrence. Thus, we report this patient with a reactive CD30+ cells infiltration following trauma.

A case of inflamed canaliform median raphe cysts

( Junghwa Yang ),( Yeon Gu Choi ),( Gyoo Huh ),( Hyeon Jeong Park ),( Yun Ho Lee ),( Jung Yup Kim ),( Sunmin Yim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Median raphe cysts are relatively rare congenital anomalies that may occur anywhere along the midline of the ventral side of the male genital area. It usually occurs as a single or a few cysts, but rarely can appear as a canaliform pattern. The pathogenesis of these cysts is not well understood, but is thought to be caused by defects in embryologic development. Most these cysts are asymptomatic until adulthood, but they can be detected earlier when trauma or secondary infections occur, accompanied by symptoms such as swelling, tenderness, and exudates. We report a case of a 5-year old boy with inflamed canaliform median raphe cysts. He presented with multiple yellowish cysts along a cord-like swelling running in the midline extending from the anterior margin of the anus to the lower pole of the scrotum. Especially, one painful scrotal lesion with exudative crusts occurred after swimming in the pool four days ago. Histopathologic findings showed tangentially sectioned invaginated keratin filled lesions with some coccoid form bacterial organisms and focal neutrophilic collections. Bacteroides fragilis was identified on the bacterial culture from the affected area. We treated his lesion with appropriate antibiotics and drainage dressing. Thus, we introduce this as a rare case of inflammatory canaliform raphe cysts in a pediatric patient.

A split-face, single-blinded, randomized controlled comparison of 532nm picosecond Nd:YAG laser versus 532nm Q-switched Nd:YAG laser in the treatment of solar lentigines

( Junghwa Yang ),( Yeon Gu Choi ),( Gyoo Huh ),( Hyeon Jeong Park ),( Yun Ho Lee ),( Sunmin Yim ),( Jung Yup Kim ),( Heun Joo Lee ),( Young-jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: 532 nm wavelength of Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser is widely used for the treatment of solar lentigines. Recently, picosecond (PS) laser is emerging as a better treatment option for solar lentigines. Objectives: To evaluate the clinical efficacy and safety of 532 nm PS and QSNY laser in a split-face design. Methods: A prospective, randomized, split-face study of 532 nm PS laser and 532 nm QSNY laser was designed. Two laser sessions were performed at 2-week intervals. Clinical improvement was assessed by the number of lentigines, melanin index from 3D camera analysis, and 5-point quartile improvement scale (QIS). Development of PIH were also assessed. Results: A total of 24 subjects (23 females and 1 male) with Fitzpatrick skin types III to IV, mean age 50 years, were enrolled. The reduction of lentigo counts was not significantly different between the two groups, but the melanin index change showed a more significant improvement in the pico-arm. (p < 0.05). QIS showed 532 nm PS laser was more effective than 532nm QSNY laser. (p < 0.05) The incidence of PIH was 5% in 532nm PS laser, and 30% in 532nm QSNY laser. Conclusion: Both 532 nm PS laser and 532 nm QSNY laser are effective for the treatment of solar lentigines, however, 532 nm PS laser removed solar lentigines more effectively with less PIH.

4차 산업혁명 시대 한국교회 진로지도 방향에 대한 제안

최중화 ( Junghwa Choi ) 한국교회교육·복지실천학회 2023 교회교육·복지실천 연구 Vol.5 No.1

The purpose of this study is to suggest the direction of youth career guidance for Korean churches in the era of the Fourth Industrial Revolution. This article also aims to once again find and reflect on the fundamental principles of ordinary but important career guidance that we all know in the Bible at this point in the 4th industrial revolution and the corona era. A few arguments include: 1) There is no vocational education in the modern sense in the Bible. However, the Bible tells us the fundamental principles and direction of career guidance. 2) Career guidance in the Bible is a little different from modern career education. Rather than focusing on ‘which job to choose’, the focus is on ‘how should I live my life?’. Ultimately, biblical career guidance deals with core values and identity. The core value and identity of the Bible is the kingdom of God enjoyed by the image of God. 3) In the rapidly diversifying era of the 4th Industrial Revolution, church career education should be interactive. It is thought that realistic and ultimate career guidance is to properly introduce the Gospel and form identity and core values as Christians. At the same time, it is necessary to introduce specialized vocational education programs that keep up with the rapidly changing society and vocational education.

온톨로지 기반 개인 미디어 메타데이터 자동 생성

최정화(Junghwa Choi),서희철(HeeCheol Seo),박영택(Youngtack Park) 한국정보과학회 2006 한국정보과학회 학술발표논문집 Vol.33 No.2B

개인 디지털 콘텐츠 증가에 따른 개인 미디어의 관리를 위해 대량의 메타데이터를 자동으로 생성하는 연구가 반드시 필요하다. 본 논문에서는 온톨로지 기반의 추론을 이용하여 개인 미디어 메타데이터를 자동으로 생성하는 방법을 제안한다. 제안한 방법은 부족한 정보로부터 적합한 의미를 추출하여 메타데이터를 자동 생성하므로 콘텐츠관리의 어려운 문제점을 해결한다. 본 논문에서 제안하는 방법을 사용자가 메모를 부착하기만 하면, 온톨로지 기반 추론을 통해 메타데이터를 자동 생성하는 방법으로 다음과 같은 세가지 기술과 특징을 갖는다. 첫째, 개인 미디어 온톨로지를 정의한다. 둘째, 미디어 메타데이터 표준을 정의한다. 미디어의 종류가 다르더라도 정의한 표준의 키워드만 추출할 수 있다면 미디어의 통합관리가 가능하다. 셋째, 메타데이터 자동 생성 기술을 연구한다. 단순히 온톨로지에 정의된 키워드의 의미만을 보지 않고, 온톨로지 기반의 추론엔진을 이용하여 사용자를 중심으로 관련 키워드의 관계를 고려한 메타데이터 생성의 정확성을 높인다. 이러한 기술을 기반으로 시맨틱 검색도 가능하며, 기존의 메타데이터 저작도구와 비교하여 보다 정확한 메타데이터 자동생성과 검색이 가능하다.

유아기 자녀를 둔 어머니의 아동권리 인식이 자녀의 행복감에 미치는 영향

최정화(Junghwa Choi),김정화(Jeongwha Kim) 한국보육지원학회 2021 한국보육지원학회지 Vol.17 No.6

Objective: This study is to confirm the effect of mothers perception of children s rights on the happiness of infants under the UN Convention on the Rights of the Child. Methods: This study was conducted on 383 mothers with children aged 3 to 5 attending daycare centers in Jeollanam-do, South Korea. Results: First, the difference in perception of children s rights according to the mother s general background did not show a significant difference in the mother s perception of children s rights, and the child s sense of happiness showed a statistically significant difference in the mother s education and child s gender. Second, there was a positive correlation between the mother s perception of child rights and the child s sense of happiness. Third, the effect of mothers perception of child rights on children s happiness was significant, and in the sub-factors, it was found that the perception of participation rights had a significant effect on children s happiness. Conclusion/Implications: In this study, it was confirmed that mothers perception of children s rights is important in promoting the happiness of early childhood children. Through this study, we would like to raise the need for parental education based on education on children s rights for mothers awareness and practice of children s rights.

유비쿼터스 환경에서의 온톨로지 기반 시간 추론

최정화(Junghwa Choi),서일홍(llHong Suh),박영택(Youngtack Park) 한국정보과학회 2006 한국정보과학회 학술발표논문집 Vol.33 No.2B

유비쿼터스 시스템은 개인화 서비스를 위한 사용자 모델링이 필요하다. 사용자 모델링은 더 정확한 컨텍스트 모델을 만들기 위한 중요한 단계이다. 본 논문에서는 컨텍스트 모델을 기반으로 사용자에게 적당한 서비스를 제공하기 위한 방법을 연구한다. 이를 위해서 우리는 개념 의존(conceptual dependency)을 이용한 온톨로지 기반 컨텍스트 모델링 방법을 제안한다. 이 모델은 관찰된 사용자 행동을 모델링한다. 우리는 사용자 행동을 모델링하기 위해서 개념 의존 이론을 기반으로 컨텍스트 온톨로지를 설계한다. 컨텍스트 모델러는 사용자 행동을 모니터하고 행동을 표현하기 위해 온톨로지 인스턴스를 생성한다. 더 정확한 행동 표현을 위해 본 연구에서는 시간 개념(temporal concept)을 기반으로 시간 추론을 사용하여 컨텍스트 모델을 구축한다. 생성된 시간 컨텍스트 모델은 온톨로지 추론을 이용하여 유비쿼터스 컴퓨팅을 위한 상위 컨텍스트의 추론이 가능하다.

초대교회의 이웃사랑의 차별성에 기초한 교회 사회복지 실천함의

최중화 ( Junghwa Choi ) 한국교회교육·복지실천학회 2018 교회교육·복지실천 연구 Vol.1 No.1

본 연구는 국가 및 사회적으로 복지 제도와 서비스가 다각화되고 교회의 사회복지 실천에 대하여도 보다 전문적이고 객관적인 평가와 기대가 요구되는 가운데, 초대교회의 이웃사랑 특성 및 동시대 그레코-로마 종교들의 이웃사랑과의 차별성을 분석하여 성경적 이웃사랑 관점을 도출함으로써 교회 사회복지 실천이 갖는 고유의 의의와 함의를 제공하고자 한다. 이러한 연구 목적에 따라 초대교회의 이웃사랑의 특성 및 차별성을 검토한 결과, 초대교회의 이웃사랑은 우선 이웃사랑의 대상이 제한적이지 않고 사회와 인종을 뛰어 넘어 도움이 필요한 사람을 모두 대상으로 한다는 점에서 유대교와 다르며, 이웃사랑이 윤리적 차원을 넘어 신앙으로 승화되었다는 점에서 그레코-로마 종교들과 구별된다. 또한 예수 그리스도의 피를 통한 회개와 성령의 역사하심이 이웃사랑을 실천하는 주요한 열쇠가 된다는 점에서 당시 다른 종교들과 확연히 다름을 볼 수 있다. 이러한 초대교회의 이웃사랑의 차별성은 오늘날의 교회 사회복지 실천에 적용될 수 있으며, 이러한 회개의 열매이자 하나님과의 관계를 비롯한 신앙의 차원, 성령의 역사하심을 통한 실현 등을 통해 교회는 사회 내 구별되는 사랑과 사회복지 실천을 다할 수 있을 것이다. The purpose of this study is to deliberate the meaning and implication of church social work practice through analyzing the distinction of the neighbor-love of the early church comparing to other religions of the Greco-Roman Era. The study first showed that objects of neighbor-love of the early church were not limited to the homogeneous community and it rather served everyone who was in need regardless of nation, race or society, which is different from that of Judaism. Secondly, the neighbor-love of the early church was developed to spirituality beyond ethical level while other religions of the Greco-Roman Era regarded love and service as ethical actions. In addition, it is repentance by the blood of Jesus Christ and action of the Holy Spirit that the neighbor-love of the early church is different from other religion of such Era. These distinctions give the meaningful implication on today’s church social work practice, which leads a distinctive love and social work practice based on repentance, faith and the action of the Holy Spirit.