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RISS 인기검색어
- 검색키워드
- 저자 : Jiu-Hong Chen (검색결과 4 건)
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Hosgood III, H. Dean,Wang, Wen-Chang,Hong, Yun-Chul,Wang, Jiu-Cun,Chen, Kexin,Chang, I-Shou,Chen, Chien-Jen,Lu, Daru,Yin, Zhihua,Wu, Chen,Zheng, Wei,Qian, Biyun,Park, Jae Yong,Kim, Yeul Hong,Chatterje Springer-Verlag 2012 HUMAN GENETICS Vol.131 No.7
<P>A recent genome-wide association study (GWAS) of subjects from Japan and South Korea reported a novel association between the TP63 locus on chromosome 3q28 and risk of lung adenocarcinoma (p = 7.3 10(-12)); however, this association did not achieve genome-wide significance (p 10(-7)) among never-smoking males or females. To determine if this association with lung cancer risk is independent of tobacco use, we genotyped the TP63 SNPs reported by the previous GWAS (rs10937405 and rs4488809) in 3,467 never-smoking female lung cancer cases and 3,787 never-smoking female controls from 10 studies conducted in Taiwan, Mainland China, South Korea, and Singapore. Genetic variation in rs10937405 was associated with risk of lung adenocarcinoma [n = 2,529 cases; p = 7.1 10(-8); allelic risk = 0.80, 95% confidence interval (CI) = 0.74-0.87]. There was also evidence of association with squamous cell carcinoma of the lung (n = 302 cases; p = 0.037; allelic risk = 0.82, 95% CI = 0.67-0.99). Our findings provide strong evidence that genetic variation in TP63 is associated with the risk of lung adenocarcinoma among Asian females in the absence of tobacco smoking.</P>
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Ren, Hong-Xuan,Chen, Xing,Huang, Xing-Jiu,Im, Maesoon,Kim, Dong-Haan,Lee, Joo-Hyung,Yoon, Jun-Bo,Gu, Ning,Liu, Jin-Huai,Choi, Yang-Kyu Royal Society of Chemistry 2009 Lab on a chip Vol.9 No.15
<P>We use a conventional and straightforward route to fabricate scalable morphology-controlled regular structures. This route is based on the etching of PDMS microlens array in CF<SUB>4</SUB> and CF<SUB>4</SUB>/O<SUB>2</SUB> plasma. PDMS microlens array can be changed to regularly isolated microdot structures array in CF<SUB>4</SUB> plasma. Microbowl shaped structures array can be reached in CF<SUB>4</SUB>/O<SUB>2</SUB> plasma. Moreover, a set of structures after CF<SUB>4</SUB> plasma treatment display superhydrophobicity, while a set of structures after CF<SUB>4</SUB>/O<SUB>2</SUB> plasma treatment present hydrophilicity. DNA molecules can be readily enriched on the hydrophilic surface. We believe that the regular structure array surfaces provide a useful inspiration towards biomolecular detection and transportation in biochips.</P> <P>Graphic Abstract</P><P>Morphology-controlled regular structures and their opposite wettabilities can be obtained based on the etching of PDMS microlens array in CF<SUB>4</SUB> and CF<SUB>4</SUB>/O<SUB>2</SUB> plasma. DNA molecules enrichment is also investigated. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b905804d'> </P>
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Jing Chen,Ji-Qing Qiu,Peng Shi,Hong-Jiu Yang 제어·로봇·시스템학회 2010 International Journal of Control, Automation, and Vol.8 No.2
In this paper, the problem of stochastic robust stability of time-varying delay neutral system with Markovian jump parameters is investigated. The jumping parameters are considered as a continuous-time, continuous state Markov process. Based on the Lyapunov-Krasovskii functional approach, a new delay-dependent stochastic stability criteria is presented in terms of LMIs. A numerical example is given to illustrate the effectiveness of the developed method.
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Kai Sun,Rui-Juan Han,Li-Jun Ma,Li-Jun Wang,Li-Gang Li,Jiu-Hong Chen 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6
Objective: To assess the image quality and effective radiation dose of prospectively electrocardiogram (ECG)-gated high-pitch spiral acquisition mode (flash mode) of dual-source CT (DSCT) coronary angiography (CTCA) in patients with high heart rates (HRs) as compared with retrospectively ECG-gated spiral acquisition mode. Materials and Methods: Two hundred and sixty-eight consecutive patients (132 female, mean age: 55 ± 11 years) with mean HR > 65 beats per minute (bpm) were prospectively included in this study. The patients were divided into two groups. Collection was performed in group A CTCA using flash mode setting at 20-30% of the R-R interval, and retrospectively ECG-gated spiral acquisition mode in group B. The image noise, contrast-to-noise ratio (CNR), image quality scores, effective radiation dose and influencing factors on image quality between the two groups were assessed. Results: There were no significant differences in image quality scores and proportions of non-diagnostic coronary artery segments between two groups (image quality scores: 1.064 ± 0.306 [group A] vs. 1.084 ± 0.327 [group B], p = 0.063; proportion of non-diagnostic coronary artery segments: segment-based analysis 1.52% (group A) vs. 1.74% (group B), p = 0.345; patient-based analysis 7.5% (group A) vs. 6.7% (group B), p = 0.812). The estimated radiation dose was 1.0 ± 0.16 mSv in group A and 7.1 ± 1.05 mSv in group B (p = 0.001). Conclusion: In conclusion, in patients with HRs > 65 bpm without cardiac arrhythmia, the prospectively high-pitch spiral-acquisition mode with image-acquired timing set at 20-30% of the R-R interval provides a similar image quality and low rate of non-diagnostic coronary segments to the retrospectively ECG-gated low-pitch spiral acquisition mode, with significant reduction of radiation exposure. Objective: To assess the image quality and effective radiation dose of prospectively electrocardiogram (ECG)-gated high-pitch spiral acquisition mode (flash mode) of dual-source CT (DSCT) coronary angiography (CTCA) in patients with high heart rates (HRs) as compared with retrospectively ECG-gated spiral acquisition mode. Materials and Methods: Two hundred and sixty-eight consecutive patients (132 female, mean age: 55 ± 11 years) with mean HR > 65 beats per minute (bpm) were prospectively included in this study. The patients were divided into two groups. Collection was performed in group A CTCA using flash mode setting at 20-30% of the R-R interval, and retrospectively ECG-gated spiral acquisition mode in group B. The image noise, contrast-to-noise ratio (CNR), image quality scores, effective radiation dose and influencing factors on image quality between the two groups were assessed. Results: There were no significant differences in image quality scores and proportions of non-diagnostic coronary artery segments between two groups (image quality scores: 1.064 ± 0.306 [group A] vs. 1.084 ± 0.327 [group B], p = 0.063; proportion of non-diagnostic coronary artery segments: segment-based analysis 1.52% (group A) vs. 1.74% (group B), p = 0.345; patient-based analysis 7.5% (group A) vs. 6.7% (group B), p = 0.812). The estimated radiation dose was 1.0 ± 0.16 mSv in group A and 7.1 ± 1.05 mSv in group B (p = 0.001). Conclusion: In conclusion, in patients with HRs > 65 bpm without cardiac arrhythmia, the prospectively high-pitch spiral-acquisition mode with image-acquired timing set at 20-30% of the R-R interval provides a similar image quality and low rate of non-diagnostic coronary segments to the retrospectively ECG-gated low-pitch spiral acquisition mode, with significant reduction of radiation exposure.
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