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      • Simultaneous Entities and Relationship Extraction from Unstructured Text

        Jingtai Zhang,Jin Liu,Xiaofeng Wang 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.6

        Entity recognition and entity relationship extraction are two very important tasks in information extraction. Most research work in the literature treats these two work independently when processing the text. This paper proposes a novel method for performing entity recognition and entity relationship extraction simultaneously from unstructured text based on Conditional Random Fields (CRFs). This method makes use of entity features, entity relationship features and features of the triples which is composed of entities and their relationship to conduct the model training. Experiment results show that this method can recognize entity and extract entity relationship effectively.

      • Synthesis of hairpin DNA mediated Au-Ag bimetallic nanomushrooms for antibacterial application

        Fu, Jingtai,Huang, Lu,Yu, Zhongning,Zhang, Zhuomin,Li, Gongke Techno-Press 2021 Advances in nano research Vol.11 No.1

        Precise control of the synthesis of bimetallic nanoparticles with specific morphology and structure is of great significance due to their excellent catalytic, optical and biological property. DNA molecules are considered as a kind of efficient templates to mediate the precise synthesis of bimetallic nanoparticles with homogeneous morphology due to their specific and controllable structure. In this study specific hairpin DNA strands were successfully utilized as templates to mediate the synthesis of special mushroom-like Au-Ag bimetallic nanoparticles with a high yield of > 90%. Several key factors greatly influencing the precise control of the morphology and UV-Vis characteristics of the proposed Au-Ag nanomushrooms during synthesis were investigated and optimized in detail, including the structure of template DNA, loading amounts of DNA, types of reductant agents and surfactants. Then, the formation mechanism of hairpin DNA mediated Au-Ag nanomushrooms was studied. Finally, the proposed Au-Ag nanomushrooms with good biocompatibility were applied for the antibacterial study by the growth curve of E. coli. The proposed Au-Ag nanomushrooms showed the effective inhibition capability for the growth of E. coli. The results suggested that these DNA mediated Au-Ag nanomushrooms possessed great potential applications for biomedical science in future.

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