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- 저자 : Jin Ming-liang (검색결과 42 건)
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Statistic Analysis on Nonuniformity of Electrical Parameters of ZnO Varistors
Jin-Liang He,Shui-Ming Chen,Se-Won Han,Han-Goo Cho,Hyung-Boo Kang 한국정보과학회 1998 Journal of Electrical Engineering and Information Vol.3 No.5
Analyzing the nonuniformity of electrical parameters of ZnO varistors is useful to select and coordinate the ZnO varistors in parallel operation to increase the protection capability of ZnO varistors. The nonuniformity of 1[mA] DC voltage and impulse residual voltage in ZnO varistors for commercial low- and high-voltage were estimated by a statistic analysis in this paper. The relative standard deviations of 1[mA] DC voltages ZnO varistors for low-voltage and rugh-voltage were 1.98[%] and 4.10[%], respectively. The respective relative standard deviations of impulse residual voltages were 2.24[%] and 3.14[%], respectively. For the distribution of 1[mA] DC voltage and impulse residual voltage, results in ZnO varistors for low- and high-voltage agreed well with the Minimum Gobble Distribution according to the Kolmogorov-Smirnov test. A close relation between the impulse residual voltage and 1[mA] DC voltage was verified by both the t-test and another test method, and the impulse residual voltage could be estimated by a voltage ratio and 1[mA] DC voltage. The current overload of ZnO varistor with reduced residual voltage was not serious at the tested deviation range by simulation analysis, therefore, there was no problem for these varistors operating in parallel.
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Jin-Fang Yin,Donghai Wang,Zhao-Ming Liang,Chong-Jian Liu,Guo-Qing Zhai,Hong Wang 한국기상학회 2018 Asia-Pacific Journal of Atmospheric Sciences Vol.54 No.1
Simulations of the severe precipitation event that occurred in the warm sector over southern China on 08 May 2014 are conducted using the Advanced Weather Research and Forecasting (WRF-ARWv3.5.1) model to investigate the roles of microphysical latent heating and surface heat fluxes during the severe precipitation processes. At first, observations from surface rain gauges and groundbased weather radars are used to evaluate the model outputs. Results show that the spatial distribution of 24-h accumulated precipitation is well reproduced, and the temporal and spatial distributions of the simulated radar reflectivity agree well with the observations. Then, several sensitive simulations are performed with the identical model configurations, except for different options in microphysical latent heating and surface heat fluxes. From the results, one of the significant findings is that the latent heating from warm rain microphysical processes heats the atmosphere in the initial phase of the precipitation and thus convective systems start by self-triggering and selforganizing, despite the fact that the environmental conditions are not favorable to the occurrence of precipitation event at the initial phase. In the case of the severe precipitation event over the warm sector, both warm and ice microphysical processes are active with the ice microphysics processes activated almost two hours later. According to the sensitive results, there is a very weak precipitation without heavy rainfall belt when microphysical latent heating is turned off. In terms of this precipitation event, the warm microphysics processes play significant roles on precipitation intensity, while the ice microphysics processes have effects on the spatial distribution of precipitation. Both surface sensible and latent heating have effects on the precipitation intensity and spatial distribution. By comparison, the surface sensible heating has a strong influence on the spatial distribution of precipitation, and the surface latent heating has only a slight impact on the precipitation intensity. The results indicate that microphysical latent heating might be an important factor for severe precipitation forecast in the warm sector over southern China. Surface sensible heating can have considerable influence on the precipitation spatial distribution and should not be neglected in the case of weak large-scale conditions with abundant water vapor in the warm sector.
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Ming Xie,Jin-Long Liang,Han-Dong Huang,Mai-Jian Wang,Tao Zhang,Xue-Feng Yang 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4
Purpose Nonylphenol (NP) is an endocrine disruptor found in products such as cleaners, plastics, and detergents. It exerts actions similar to endogenous 17-estradiol (E2) and is reported to influence various cancers. However, its role in colon cancer remains elusive. Materials and Methods Colon cancer cell lines COLO 205 and SW480 were employed in our study. The cells were treated with NP or E2 followed by measurement of apoptosis and proliferation using flow cytometry and MTT assays, respectively. G protein–coupled estrogen receptor 30 (GPR30) expression was visualized using immunofluorescence and Western blot. To investigate the underlying mechanism, the expression levels of GPR30, p-protein kinase A (PKA), c-myc, cyclin D1, and ERK1/2 were analyzed using Western blot. Meanwhile, the GPR30 antagonist G15 was utilized to validate the role of GPR30 in colon cancer progression. Finally, the effect of a GPR30 inhibitor on tumor growth was determined in vivo using tumor xenograft mouse models. Results NP facilitated the proliferation of colon cancer cells and induced apoptosis failure in vitro. Western blot revealed increased GPR30 expression levels in response to NP treatment. Cyclin D1, p-PKA, c-myc, and proliferating cell nuclear antigen, proteins that regulate the cell cycle, were all upregulated by NP, and NP-mediated ERK1/2 activation and subsequent cell proliferation were abrogated by the GPR30 inhibitor G15. Moreover, colon cancer mice that received G15 administration demonstrated impaired tumor growth in vivo. Conclusion Low dose NP promotes the growth of colon tumors through GPR30-mediated activation of ERK1/2 signaling.
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Ming, Jun,Wu, Yingqiang,Liang, Guanfeng,Park, Jin-Bum,Zhao, Fengyu,Sun, Yang-Kook The Royal Society of Chemistry 2013 Green chemistry Vol.15 No.10
<P>The salt effect of Na<SUB><I>x</I></SUB>A (A = SO<SUB>4</SUB><SUP>2−</SUP>, Cl<SUP>−</SUP>, NO<SUB>3</SUB><SUP>−</SUP>, <I>etc</I>.) on the hydrothermal carbonization of biomass is reported. It is a new catalyst and recyclable template to more simply and effectively prepare carbon-based materials, such as porous carbon-coated anode materials (<I>e.g.</I>, Fe<SUB>3</SUB>O<SUB>4</SUB>@porous-C) in lithium-ion battery applications with enhanced performance.</P> <P>Graphic Abstract</P><P>The sodium salt effect on hydrothermal carbonization of biomass and as a catalyst for carbon-based nanostructured materials for lithium-ion battery applications is reported. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3gc40480c'> </P>
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Li, Ming-Huan,Shang, Dong-Ping,Chen, Chen,Xu, Liang,Huang, Yong,Kong, Li,Yu, Jin-Ming Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Background: The purpose of this study was to prospectively evaluate the predictive value of perfusion computed tomography (CT) for response of local advanced esophageal carcinoma to radiotherapy and chemotherapy. Materials and Methods: Before any treatment, forty-three local advanced esophageal squamous cell carcinomas were prospectively evaluated by perfusion scan with 16-row CT from June 2009 to January 2012. Perfusion parameters, including perfusion (BF), peak enhanced density (PED), blood volume (BV), and time to peak (TTP) were measured using Philips perfusion software. Seventeen cases received definitive radiotherapy and 26 received concurrent chemo-radiotherapy. The response was evaluated by CT scan and esophagography. Differences in perfusion parameters between responders and non-responders were analyzed, and ROCs were used to assess predictive value of the baseline parameters for treatment response. Results: There were 25 responders (R) and 18 non-responders (NR). Responders showed significantly higher BF (R:34.1 ml/100g/min vs NR: 25.0 ml/100g/min, p=0.001), BV (23.2 ml/100g vs 18.3 ml/100g, p=0.009) and PED (32.5 HU vs 28.32HU, P=0.003) than non-responders. But the baseline TTP (R: 38.2s vs NR: 44.10s, p=0.172) had no difference in the two groups. For baseline BF, a threshold of 36.1 ml/100g/min achieved a sensitivity of 56%, and a specificity of 94.4% for detection of clinical responders from non-responders. Conclusions: The results suggest that the perfusion CT can provide some helpful information for identifying tumors that may respond to radio-chemotherapy.
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Zhao-Ming Liang,Ying Liu,Jin-Fang Yin,Chong-Jian Liu 한국기상학회 2019 Asia-Pacific Journal of Atmospheric Sciences Vol.55 No.2
The effects of a synoptic situation on the motion and development of warm-sector mesoscale convective systems (MCSs) in a heavy rainfall event occurred in South China on 8 May 2014 are investigated using high-resolution observational data and ERA-Interim data. The results show that the blocking of an eastward moving low-level trough over southwestern China by a stable anticyclone over eastern China induced strong southerly winds ahead of the trough and an eastward vertical slant of the wind speed maximum. Consequently, a southeastward low-level wind shear formed in the region under the southerly jet, which caused a southeastward turning of the motion of a large inland MCS. Meanwhile, a northeastward/eastward low-level wind shear formed in the region under the east side of the southerly jet, leading to northeastward/eastward movement of some small MCSs in the coastal region. The continuous merging of the southeastward-moving MCS with the northeastward/eastward-moving MCSs resulted in heavy rainfall along the coastal region. On the other hand, the intensification and expansion of associated low and high mean-sea-level pressure (MSLP) centers caused southeastward migration of strong boundary-layer moisture flux convergence and high convective available potential energy zones, which promoted the persistent development of the large MCS and the later development of the small MCSs. Moreover, the strong boundary-layer southeasterly winds associated with the high MSLP center continuously enhanced the frontal ascent of the large MCS. These southeasterly winds also triggered the small MCSs through the convergence induced by differential surface friction between the land and sea or the convergence of them with the southwesterly winds from the South China Sea.
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Glycididazole Sodium Combined with Radiochemotherapy for Locally Advanced Nasopharyngeal Carcinoma
Li, Ming-Yi,Liu, Jin-Quan,Chen, Dong-Ping,Qi, Bin,Liang, Yu-Ying,Yin, Wen-Jing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6
Background: To evaluate efficacy and side effects of glycididazole sodium (CMNa) combined with chemotherapy (cisplatin plus 5-FU/folic acid, PLF) and radiotherapy in treating patients with locally advanced nasopharyngeal carcinoma. Materials and Methods: Patients with III~IV stage nasopharyngeal carcinoma (NPC),were randomly divided into treatment group (46 patients) and control group (45 patients). Both groups received radiotherapy concomitant with PLF chemotherapy. The treatment group at the same time cwas given CMNa ($800mg/m^2$ before radiotherapy), by l h intravenous drip, three times a week. Results: When the dose of radiation was over 60 Gy, complete response rates of nasopharyngeal tumor and lymph node metastases in treatment group were significantly higher than in the control group (93.5% vs 77.8%; 89.1% vs 93.5%, p<0.05). Three months after radiotherapy, complete response rate of nasopharynx cancer and lymph node metastases in treatment group was both 97.8%, again higher than in the control group (84.4% and 82.2%) (p<0.05). In the treatment group, 1, 3, 5 year disease-free survival rates were 95.7%, 86.7% and 54.5%; and in control group, the corresponding disease-free survival rates were 93.3%, 66.2% and 38.6%, respectively, the difference being statistically significant (log-rank =5.887, p=0.015). One, 3, 5 year overall survival rates in two groups of patients were 97.8%, 93.5%, 70.4% and 95.5%, 88.07%, 48.4%, respectively, again with a statistically significant difference (log-rank=6.470, p=0.011). Acute toxicity and long-term radiotherapy related toxicity in the two groups did not differ (p>0.05). Conclusions: Glycididazole sodium could improve curative effects without increasing adverse reactions when treating paitents with locally advanced nasopharyngeal carcinoma.
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Wang, Yun-Liang,Dong, Feng-Lin,Yang, Jian,Li, Zhi,Zhi, Qiao-Ming,Zhao, Xin,Yang, Yong,Li, De-Chun,Shen, Xiao-Chun,Zhou, Jin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Background: Epidermal growth factor-like domain multiple 7 (EGFL7), a secreted protein specifically expressed by endothelial cells during embryogenesis, recently was identified as a critical gene in tumor metastasis. Epithelial-mesenchymal transition (EMT) was found to be closely related with tumor progression. Accordingly, it is important to investigate the migration and EMT change after knock-down of EGFL7 gene expression in human pancreatic cancer cells. Materials and Methods: EGFL7 expression was firstly testified in 4 pancreatic cancer cell lines by real-time polymerase chain reaction (Real-time PCR) and western blot, and the highest expression of EGFL7 was found in PANC-1 cell line. Then, PANC-1 cells transfected with small interference RNA (siRNA) of EGFL7 using plasmid vector were named si-PANC-1, while transfected with negative control plasmid vector were called NC-PANC-1. Transwell assay was used to analyze the migration of PANC-1 cells. Real-time PCR and western blotting were used to detect the expression change of EGFL7 gene, EMT markers like E-Cadherin, N-Cadherin, Vimentin, Fibronectin and transcription factors like snail, slug in PANC-1, NCPANC-1, and si-PANC-1 cells, respectively. Results: After successful plasmid transfection, EGFL7 gene were dramatically knock-down by RNA interference in si-PANC-1 group. Meanwhile, migration ability decreased significantly, compared with PANC-1 and NC-PANC-1 group. Meanwhile, the expression of epithelial phenotype marker E-Cadherin increased and that of mesenchymal phenotype markers N-Cadherin, Vimentin, Fibronectin dramatically decreased in si-PANC-1 group, indicating a reversion of EMT. Also, transcription factors snail and slug decreased significantly after RNA interference. Conclusions: Current study suggested that highly-expressed EGFL7 promotes migration of PANC-1 cells and acts through transcription factors snail and slug to induce EMT, and further study is needed to confirm this issue.
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