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      • KCI등재

        Incidence of Listeria in Egyptian Meat and Dairy Samples

        Ahmed Abdel-Rhman Ismaiel,Ali El-Sayed Ali,Gamal Enan 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.1

        A total of 180 food samples including meat(raw lean beef, frozen lean beef, and frozen chicken) anddairy products (raw milk, Zabady and Kareesh cheese)were analysed for Listeria. Isolates were differentiatedusing morphological, cultural, and biochemical tests and anAPI-Listeria kit. Zabady cheese was completely free ofListeria. The highest incidence rate (13.33%) was in frozenlean beef. Raw lean beef and milk products showed anincidence rate of 6.67%. The lowest incidence rate (3.33%)was in Kareesh cheese and frozen chicken meat samples. L. monocytogenes showed the lowest incidence rate(0.55%), isolated from one frozen lean beef sample. L. ivanovii and L. grayi showed the highest incidence rate(2.22%), isolated from 4 samples. L. innocua and L. seeligeri were positive in 3 samples (1.67%), and L. welshimeri in 2 samples (1.11%). L. monocytogenes and L. ivanovii were positive for virulence factors (hemolyticproperties, and extracellular enzyme activities).

      • SCIESCOPUSKCI등재

        Some Nucleophilic Substitutions in 2,4- and 2,4,8-Trichloro- pyrido [3,2-d] pyrimidines

        Boyomi, Said M.,Ismaiel, Abdel-Kader M.,Eisa, Hassan M.,El-Kerdawy, Mohamed M. The Pharmaceutical Society of Korea 1989 Archives of Pharmacal Research Vol.12 No.1

        Reaction of 6-(acetoxymethyl) -2,4-dichloropyrido [3,2-d] pyrimidine (I) with some nucleophiles was investigated. When I reacted with sodium azide afforded 2,4-diazido derivative (II). Treatment of II with sodium hydroxide underwent cyclization of the 2-azido group to tetrazolo, replacement of 4-azido group by hydroxide ion, and hydrolysis of 6-ace-foxy moiety to hydroxy methyl derivative (III). While, reaction of I with hydrazine hydrate resulted in the formation of 2,4 dihydrozino-6-hydroxymethyl derivative (lV).

      • KCI등재

        Food Group Intake of Pregnant Jordanian Women Based on the Three Pregnancy Trimesters

        Reema Tayyem,Sabika S. Allehdan,Narmeen J. Al-Awwad,Razan M. Alatrash,Ismaiel Abu Mahfouz,Fida Alasali 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.4

        Inadequate diets have adverse effects on maternal, fetal, and, possibly, childhood health. This cross-sectional study aimed to examine daily food group intake of pregnant Jordanian women during the three pregnancy trimesters and to compare these to the recommended servings of the five food groups reported by The United States Department of Agriculture and My Plate Plan. A total of 283 pregnant Jordanian women were recruited during their antenatal visits. Data were obtained by interviewer-administered structured questionnaires. Our results showed that 1.1% of participants consumed the recommended number of servings for all five food groups during pregnancy and 10.2% did not consume the minimum number of servings of the five food groups. Nearly half of the participants in the first trimester met the recommended daily servings for three food groups but only approximately two-third of participants met the minimum recommended daily servings for one or two food groups in the second and third trimesters. Consumption of grains and sweets was significantly higher in the third trimester compared with the first and second trimesters. Overall, the majority of pregnant Jordanian women in this study did not consume the recommended number of servings for all five food groups during pregnancy.

      • KCI등재후보

        Nicotine impact on rat substantia nigra compacta

        Sanaa A M Elgayar,Ola A Hussein,Heba A Mubarak,Amany M Ismaiel,Asmaa M.S. Gomaa 대한해부학회 2021 Anatomy & Cell Biology Vol.54 No.1

        Nicotine neuronal interactions exert an adverse potential in some brain regions and a significant link has been established between tobacco smoke/nicotine and vascular impairment. This work addresses nicotine impact on various components of the substantia nigra compacta (SNc) in rat. Twenty adult male Albino rats were divided equally into two groups: Group I, vehicle-control group (received saline [1 ml/kg body weight intra peritoneally] for 11 days). Group II; nicotine group (received 1.5 mg/kg body weight/day Sc) for 11 days. Nicotine levels were detected in the serum. Specimens were taken from the mid brain, processed and examined using biochemical, immunohistochemical, ultrastructural and morphometric techniques. In nicotine group, biochemical analysis revealed reduction in total antioxidant capacity (TAC), decrease in dopamine and malondialdehyde (MDA) levels. The mean number of light cells, and the mean surface area of nerve cells/field were significantly reduced, with an increase of dark cells were found in nicotine group compared to control. Immunoreactivity in nicotine group revealed an increase in neuronal α-synuclein, reduction in tyrosine hydroxylase enzyme, an increase in caspase 3 and ultrastructure changes suggestive of neuronal apopto. The blood capillaries were markedly affected. Nicotine induced endothelial and pericytic apoptotic changes, irregular lumena and indistinct endothelial junctional complex. Nicotine administered subcutaneously in a small dose may have a deleterious effect on SNc, mainly involving dopaminergic neurons and blood capillaries. This effect seems to be secondary to an oxidative stress that might be produced by reduced TAC and increased MDA levels.

      • Implications of Sex Hormone Receptor Gene Expression in the Predominance of Hepatocellular Carcinoma in Males: Role of Natural Products

        Ahmed, Hanaa H,Shousha, Wafaa Gh,Shalby, Aziza B,El-Mezayen, Hatem A,Ismaiel, Nora N,Mahmoud, Nadia S Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

        The present study was planned to investigate the role of sex hormone receptor gene expression in the pathogenesis of hepatocellular carcinoma (HCC). Adult male Wistar rats were divided into seven groups. Group (1) was negative control. Groups (2), (5), (6), and (7) were orally administered with N-nitrosodiethylamine for the induction of HCC, then group (2) was left untreated, group (5) was orally treated with curcumin, group (6) was orally treated with carvacrol, and group (7) was intraperitoneally injected with doxorubicin, whereas groups (3) and (4) were orally administered only curcumin and carvacrol, respectively. The HCC group showed significant upregulation in the androgen receptor (AR) and the estrogen receptor-alpha ($ER{\alpha}$) gene expression levels in the liver tissue. On the contrary, HCC groups treated with either curcumin or carvacrol showed significant downregulation in AR and $ER{\alpha}$ gene expression levels in the liver tissue. In conclusion, the obtained data highlight that both AR and $ER{\alpha}$ but not estrogen receptor-beta ($ER{\beta}$) gene expression may contribute to the male prevalence of HCC induced in male rats. Interestingly, both curcumin and carvacrol were found to have a promising potency in alleviating the male predominating HCC.

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