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      • KCI등재

        Flux‑coupling fault current limiter design for VSC DC grids

        Jun Xu,Lei Gao,Guangyang Zhou,Huiyuan Zhang 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.1

        DC circuit breakers (DCCBs) are used to clear short-circuit faults in several milliseconds. However, short-circuit fault current can reach extreme values. Fault current limiters (FCLs) can present high inductance values during the short-circuit fault period. Thus, they have received considerable attention for reducing the high current breaking requirements of DCCBs. Three types of magnetic flux-coupling solid-state FCLs are designed in this paper, which include mutual inductors and several power electronic switches. In addition, the FCL impedance can be controlled by power electronic switches. By comparing the current limit capacities and structural complexities among the three types of FCLs, a more applicable limiter referred to as a flux-coupling DC current limiter (FCDCCL) can be installed on VSC DC grids. Finally, a simulation model is built in PSCAD/EMTDC based on a ± 10 kV/400 A DC system. The simulation results verify that a significant change in the limiting current can be achieved by the proposed FCDCCL, which can be extended to actual VSC DC grids.

      • KCI등재

        Novel Ceramides from Aerial Parts of Saussurea involucrata Kar. et. Kir.

        Wei Wu,Yang Qu,Huiyuan Gao,Jingyu Yang,Jianguo Xu,Lijun Wu 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.9

        Novel ceramides, together with nine known compounds were isolated from aerial parts of the Saussurea involucrata Kar. et. Kir. The novel structures were determined by spectroscopic methods and microscale chemical degradation. The ceramides showed appreciable cytotoxicity against three human tumor cell lines including human promyelocytic leukemia (HL-60), human melanoma (A375-S2) and human cervical carcinoma (HeLa) cell lines. The results suggested that this class of ceramides may have potential as an antitumor agent.

      • SCIESCOPUSKCI등재

        Two Novel A-seco-Rearranged Lanostane Triterpenoids From Abies Sachalinensis

        Sun, Bohang,Hou, Bailing,Huang, Jian,Wu, Lijun,Kuroyanagi, Masonori,Gao, Huiyuan 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.12

        Further chemical study led to two new A-seco-rearranged lanostane triterpenoid derivatives (1-2) and one known compound Abiesanolide C (3) from the ethyl acetate (EtOAc) soluble fraction of the MeOH extract of Abies sachalinensis needles. The new compounds were identified as 3,4-seco-8-($14{\rightarrow}13R$)abeo-17, l3-friedo-$9{\beta}$-lanosta-4(28), 7, 14, 24-tetraen- 26,23-olide-23-hydroxy-3-oic acid and methyl-3,4-seco-8-($14{\rightarrow}13R$) abeo-17,13-friedo-$9{\beta}$-lanosta-4(28), 7, 14, 24-tetraen-26,23-olide-23-hydroxy-3-oate, respectively. Structural determination of these compounds were carried out by the spectral studies especially by the two digital (2D)-NMR and high-resolution (HR)-MS experiences.

      • KCI등재

        Two Novel A-seco-Rearranged Lanostane Triterpenoids From Abies Sachalinensis

        Bohang Sun,Bailing Hou,Jian Huang,Lijun Wu,Masonori Kuroyanagi,Huiyuan Gao 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.12

        Further chemical study led to two new A-seco-rearranged lanostane triterpenoid derivatives (1-2) and one known compound Abiesanolide C (3) from the ethyl acetate (EtOAc) soluble fraction of the MeOH extract of Abies sachalinensis needles. The new compounds were identified as 3,4-seco-8-(14→13R)abeo-17,13-friedo-9β-lanosta-4(28), 7, 14, 24-tetraen-26,23-olide-23-hydroxy-3-oic acid and methyl-3,4-seco-8-(14→13R) abeo-17,13-friedo-9β-lanosta-4(28), 7, 14, 24-tetraen-26,23-olide-23- hydroxy-3-oate, respectively. Structural determination of these compounds were carried out by the spectral studies especially by the two digital (2D)-NMR and high-resolution (HR)-MS experiences.

      • KCI등재

        Quinetides: diverse posttranslational modified peptides of ribonuclease-like storage protein from Panax quinquefolius as markers for differentiating ginseng species

        Qiang Zhao,Yunpeng Bai,Dan Liu,Nan Zhao,Huiyuan Gao,Xiaozhe Zhang 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.5

        Background: Peptides have diverse and important physiological roles in plants and are ideal markers for species identification. It is unclear whether there are specific peptides in Panax quinquefolius L. (PQ). The aims of this study were to identify Quinetides, a series of diverse posttranslational modified native peptides of the ribonuclease-like storage protein (ginseng major protein), from PQ to explore novel peptide markers and develop a new method to distinguish PQ from Panax ginseng. Methods: We used different fragmentation modes in the LTQ Orbitrap analysis to identify the enriched Quinetide targets of PQ, and we discovered Quinetide markers of PQ and P. ginseng using ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry analysis. These “peptide markers” were validated by simultaneously monitoring Rf and F11 as standard ginsenosides. Results: We discovered 100 Quinetides of PQ with various post-translational modifications (PTMs), including a series of glycopeptides, all of which originated from the protein ginseng major protein. We effectively distinguished PQ from P. ginseng using new “peptide markers.” Four unique peptides (Quinetides TP6 and TP7 as markers of PQ and Quinetides TP8 and TP9 as markers of P. ginseng) and their associated glycosylation products were discovered in PQ and P. ginseng. Conclusion: We provide specific information on PQ peptides and propose the clinical application of peptide markers to distinguish PQ from P. ginseng.

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