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( Hongtao Liu ),( Seng Zhu ),( Yingying Sun ),( Na Li ),( Jingmin Gu ),( Changjiang Sun ),( Xin Feng ),( Wenyu Han ),( Jianxia Jiang ),( Liancheng Lei ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.1
Meningitis caused by Streptococcus suis serotype 2 (S. suis 2) is a great threat to the pig industry and human health. Virulence factors associated with the pathogenesis of meningitis have yet to be clearly defined, even though many potential S. suis 2 virulence factors have been identified. This greatly hinders the progress of S. suis 2 meningitis pathogenesis research. In this study, a co-culture blood-brain barrier (BBB) model was established using primary porcine brain microvascular endothelial cells and astrocytes, and the whole genome library of S. suis 2 was constructed using phage display technology. Finally, a total of 14 potential virulence factors contributing to S. suis 2 adherence to and invasion of the BBB were selected by analyzing the interactions between the phage library and the co-culture model. Twelve of these factors have not been previously reported in meningitis-related research. The data provide valuable insight into the pathogenesis of S. suis 2 meningitis and potential targets for the development of drug therapies.
A phosphorene–graphene hybrid material as a high-capacity anode for sodium-ion batteries
Sun, Jie,Lee, Hyun-Wook,Pasta, Mauro,Yuan, Hongtao,Zheng, Guangyuan,Sun, Yongming,Li, Yuzhang,Cui, Yi Nature Publishing Group 2015 Nature nanotechnology Vol.10 No.11
Sodium-ion batteries have recently attracted significant attention as an alternative to lithium-ion batteries because sodium sources do not present the geopolitical issues that lithium sources might. Although recent reports on cathode materials for sodium-ion batteries have demonstrated performances comparable to their lithium-ion counterparts, the major scientific challenge for a competitive sodium-ion battery technology is to develop viable anode materials. Here we show that a hybrid material made out of a few phosphorene layers sandwiched between graphene layers shows a specific capacity of 2,440 mA h g<SUP>−1</SUP> (calculated using the mass of phosphorus only) at a current density of 0.05 A g<SUP>−1</SUP> and an 83% capacity retention after 100 cycles while operating between 0 and 1.5 V. Using in situ transmission electron microscopy and ex situ X-ray diffraction techniques, we explain the large capacity of our anode through a dual mechanism of intercalation of sodium ions along the x axis of the phosphorene layers followed by the formation of a Na<SUB>3</SUB>P alloy. The presence of graphene layers in the hybrid material works as a mechanical backbone and an electrical highway, ensuring that a suitable elastic buffer space accommodates the anisotropic expansion of phosphorene layers along the y and z axial directions for stable cycling operation.
( Hongtao Yu ),( Lijun Sun ),( Fuzhi Zhang ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.9
Collaborative filtering recommender systems are vulnerable to shilling attacks in which malicious users may inject biased profiles to promote or demote a particular item being recommended. To tackle this problem, many robust collaborative recommendation methods have been presented. Unfortunately, the robustness of most methods is improved at the expense of prediction accuracy. In this paper, we construct a robust Bayesian probabilistic matrix factorization model for collaborative filtering recommender systems by incorporating the detection of user anomaly rating behaviors. We first detect the anomaly rating behaviors of users by the modified K-means algorithm and target item identification method to generate an indicator matrix of attack users. Then we incorporate the indicator matrix of attack users to construct a robust Bayesian probabilistic matrix factorization model and based on which a robust collaborative recommendation algorithm is devised. The experimental results on the MovieLens and Netflix datasets show that our model can significantly improve the robustness and recommendation accuracy compared with three baseline methods.
Studies on Ionic Conduction in Ce0.95Eu0.05P2O7 at Intermediate Temperatures
Hongtao Wang,Lin Sun,Chunhua Luo,Suhua Fan 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.5
In this study, an intermediate temperature ionic conductor, Ce0.95Eu0.05P2O7, was prepared by solid state reaction. The variation of conductivities with the pressure pH2O or time were studied. The highest conductivity of Ce0.95Eu0.05P2O7 sample was observed in dry air atmosphere at 300 °C to be 1.1 × 10−4 S·cm−1 and in wet air atmosphere (pH2O = 7.4 × 103 Pa) at 100 °C to be 1.4 × 10−3 S·cm−1, respectively. The log σ ~ log (pO2) plot result indicated that Ce0.95Eu0.05P2O7 was almost a pure ionic conductor under high oxygen partial pressure and a mixed conductor of ion and electron under low oxygen partial pressure.
Wang, Hongtao,Sun, Lin,Luo, Chunhua,Fan, Suhua Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.5
In this study, an intermediate temperature ionic conductor, $Ce_{0.95}Eu_{0.05}P_2O_7$, was prepared by solid state reaction. The variation of conductivities with the pressure $pH_2O$ or time were studied. The highest conductivity of $Ce_{0.95}Eu_{0.05}P_2O_7$ sample was observed in dry air atmosphere at $300^{\circ}C$ to be $1.1{\times}10^{-4}S{\cdot}cm^{-1}$ and in wet air atmosphere ($pH_2O=7.4{\times}10^3Pa$) at $100^{\circ}C$ to be $1.4{\times}10^{-3}S{\cdot}cm^{-1}$, respectively. The log ${\sigma}$ ~ log ($pO_2$) plot result indicated that $Ce_{0.95}Eu_{0.05}P_2O_7$ was almost a pure ionic conductor under high oxygen partial pressure and a mixed conductor of ion and electron under low oxygen partial pressure.
Tingting Xie,Hongtao Hu,Donghui Chen,Pengzhe Sun 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.7
(B4C/C)-β-PbO2 electrodes were prepared by high-pressure molding technique and characterized by X-ray diffraction, scanning electron microscopy, polarization curves, cyclic voltammetry curves, and corrosion resistance test. In this paper, the effects of initial concentration, current density, electrolyte concentration, pH, and electrode spacing on tetracycline hydrochloride (TCH) degradation were investigated. Results indicated that modified electrode had high electrochemical activities, high oxygen evolution potential, and excellent corrosion resistance. The maximum removal rate of TCH could reach 90.87% at initial concentration of 300 mg/L after 120 min electrolysis with Na2SO4 concentration of 0.2 mol/L, electrode spacing of 1 cm, current density of 30 mA/cm2, and pH 3. Pseudo-first-order kinetics equation was followed during electrocatalytic degradation of TCH with 20%(B4C/C)-β-PbO2 electrode.