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Bonita Hampton Research Institute of Asian Women Sookmyung Women' 2005 Asian Women Vol.21 No.-
The purpose of this paper is to describe the cultural context within which African American women embrace spirituality and religion as coping strategies to deal with clinical diagnosis of HIV/AIDS. The paper is part of an on going research project began in 1992 to investigate the impact of HIV/AIDS on the lives of African American women with the virus. It utilizes data collected in face to face audio taped interviews with respondents obtained from three New York State agencies that provide services to people with the virus.
Peroxiredoxins and the Regulation of Cell Death
Hampton, Mark B.,O'Connor, Karina M. Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.1
Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.
Tree-Based Ensemble Methods: Predicting Asphalt Mixture Dynamic Modulus for Flexible Pavement Design
Hampton Worthey,Jidong J. Yang,S. Sonny Kim 대한토목학회 2021 KSCE Journal of Civil Engineering Vol.25 No.11
The hot mix asphalt (HMA) dynamic modulus (|E*|), or stress/strain response measurement under dynamic loading, is considered the primary mechanical property input for flexible pavement in the Mechanistic-Empirical Pavement Design Guide (MEPDG). The current MEPDG software, AASHTOWare Pavement ME Design (PMED) Version 2.5, employs the Witczak equation for |E*| estimation when laboratory-measured |E*| data is unavailable. This study investigates the feasibility of developing alternative |E*| prediction models with modern machine learning techniques based on an established data library of Georgia HMA mixtures involving varying binder sources, binder grades, and nominal maximum aggregate sizes. Specifically, tree-based ensemble methods, including bagging, random forest, and gradient boosting, were applied considering their superior performance, and balanced versatility and interpretability. The results revealed that the gradient boosting model produced the most accurate predictions with an R2 coefficient of determination of 0.982 as compared to the nationally calibrated Witczak model, which has an R2 of 0.392, using the same test data set. The stark discrepancy in the |E*| predictions emphasizes the need of local calibration for the MEPDG models and the high potential for developing greatly improved models using modern machine learning techniques with the local data sources. Ultimately, this study provides an excellent example for other state highway agencies to follow to facilitate their MEPDG implementation.
The Circle-Dance of God: Toward a Trinitarian Theology of Youth Ministry
James K. Hampton 한국기독교교육정보학회 2007 Journal of Christian education information tech Vol.0 No.11
Historically, youth ministry as a discipline has not given proper weight to the task of theology, instead focusing almost exclusively on the social sciences. As a result, it has tended to fall prey to the multiplicity of youth ministry approaches that are pervasive, often adopting methods that are antithetical to one’s specific theological tradition. Addressing two specific adolescent developmental needs (identity formation and faith development), this paper seeks to and propose a move toward a theology of youth ministry based on the perichoresis of the trinity, specifically the community, dynamism, and self-giving love of the Godhead. Using these Trinitarian categories, a proposal toward what youth ministry should look like will be proposed.
Peroxiredoxins and the Regulation of Cell Death
Mark B. Hampton,Karina M. O'Connor 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.1
Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.