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Mehri, Fereshteh,Bashirian, Saeid,Khazaei, Salman,Jenabi, Ensiyeh The Korean Pediatric Society 2021 Clinical and Experimental Pediatrics (CEP) Vol.64 No.6
Background: The effect of exposure to environmental factors on autism spectrum disorders (ASD), especially during pregnancy, is unclear. Purpose: This meta-analysis investigated the association between exposure to pesticides and polychlorinated biphenyls (PCBs) during pregnancy and ASD risk among children. Methods: We searched Scopus, PubMed, Web of Science, and ProQuest for articles published through September 2019. Random-effects models were used to examine the association among studies using pooled odds ratios (ORs) and their 95% confidence intervals (CI). I2 tests were used to measure interstudy heterogeneity. Results: The pooled OR indicated a significant association between PCB and pesticide exposure during pregnancy and ASD risk among children (OR, 1.80; 95% CI, 1.26-2.34; and OR, 1.20; 95% CI, 1.02-1.39), respectively. Conclusion: Findings of the present study indicate that exposure to pesticides and PCBs during pregnancy may affect the risk of ASD among children.
Mehri, Fereshteh,Jenabi, Ensiyeh,Bashirian, Saeed,Shahna, Farshid Ghorbani,Khazaei, Salman Occupational Safety and Health Research Institute 2020 Safety and health at work Vol.11 No.2
Background: Rheumatoid arthritis (RA) is an autoimmune disease with systemic inflammatory arthritis. This meta-analysis was conducted to examine the association between occupational exposure to silica and the risk of developing RA among different workers. Methods: In this meta-analysis, we searched relevant published studies using major electronic databases including Scopus, PubMed, ISI Web of Science, and Google Scholar search engine up to October 2019, and the references of retrieved articles were also checked for further possible sources. A random-effects model was used to account for heterogeneity among the results of the studies using the pooled odds ratios (ORs) and their 95% confidence intervals (CIs). The Q-statistic and I<SUP>2</SUP> tests were calculated to assess heterogeneity between the studies. Results: The pooled calculation of OR indicated a significant association between occupational exposure to silica and risk of developing RA among different workers (OR = 2.59, 95% CI = 1.73 to 3.45). In addition, the pooled estimates of OR in smokers were statistically significant (OR = 2.49, 95% CI = 1.13 to 3.86). Conclusions: The findings of the present study reveal that occupational exposure to silica may be associated with increased risk of developing RA.
Safety Evaluation of the Lighting at the Entrance of a Very Long Road Tunnel: A Case Study in Ilam
Mehri, Ahmad,Hajizadeh, Roohalah,Dehghan, Somayeh Farhang,Nassiri, Parvin,Jafari, Sayed Mohammad,Taheri, Fereshteh,Zakerian, Seyed Abolfazl Occupational Safety and Health Research Institute 2017 Safety and health at work Vol.8 No.2
Background: At the entrance of a tunnel, reflection of sunlight from the surrounding environment and a lack of adequate lighting usually cause some vision problems. The purpose of this study was to perform a safety evaluation of lighting on a very long road in Ilam, Iran. Methods: The average luminance was measured using a luminance meter (model S3; Hagner, Solna, Sweden). A camera (model 108, 35-mm single-lens reflex; Yashica, Nagano, Japan) was used to take photographs of the safe stopping distance from the tunnel entrance. Equivalent luminance was determined according to the Holliday polar diagram. Results: Considering the average luminance at the tunnel entrance ($116.7cd/m^2$) and using Adrian's equation, the safe level of lighting at the entrance of the tunnel was determined to be 0.7. Conclusion: A comparison between the results of the safe levels of lighting at the entrance of the tunnel and the De Boer scale showed that the phenomenon of black holes is created at the tunnel entrance. This may lead to a misadaptation of the drivers' eyes to the change in luminance level at the entrance of the tunnel, thereby increasing the risk of road accidents in this zone.
Safety Evaluation of the Lighting at the Entrance of a Very Long Road Tunnel: A Case Study in Ilam
Ahmad Mehri,Roohalah Hajizadeh,Somayeh Farhang Dehghan,Parvin Nassiri,Sayed Mohammad Jafari,Fereshteh Taheri,Seyed Abolfazl Zakerian 한국산업안전보건공단 산업안전보건연구원 2017 Safety and health at work Vol.8 No.2
ackground At the entrance of a tunnel, reflection of sunlight from the surrounding environment and a lack of adequate lighting usually cause some vision problems. The purpose of this study was to perform a safety evaluation of lighting on a very long road in Ilam, Iran. Methods The average luminance was measured using a luminance meter (model S3; Hagner, Solna, Sweden). A camera (model 108, 35-mm single-lens reflex; Yashica, Nagano, Japan) was used to take photographs of the safe stopping distance from the tunnel entrance. Equivalent luminance was determined according to the Holliday polar diagram. Results Considering the average luminance at the tunnel entrance (116.7 cd/m2) and using Adrian's equation, the safe level of lighting at the entrance of the tunnel was determined to be 0.7. Conclusion A comparison between the results of the safe levels of lighting at the entrance of the tunnel and the De Boer scale showed that the phenomenon of black holes is created at the tunnel entrance. This may lead to a misadaptation of the drivers’ eyes to the change in luminance level at the entrance of the tunnel, thereby increasing the risk of road accidents in this zone.
The Effects of Resveratrol on Silica-Induced Lung Oxidative Stress and Inflammation in Rat
Esfahani Maryam,Rahbar Amir Hossein,Asl Sara Soleimani,Bashirian Saed,Mir Moeini Effat Sadat,Mehri Fereshteh 한국산업안전보건공단 산업안전보건연구원 2023 Safety and health at work Vol.14 No.1
Background: Chronic exposure to silica is related with the provocation of an inflammatory response and oxidative stress mechanism. Vitamin D has multiple benefits in biological activities particularly respiratory system disease. Method: In this research, 20 male Wistar rats were randomly allocated into four groups (5 rats /group) as follow:Group1 received saline as (negative control) group. The group 2 received a single IT instillation of silica (positive control) group; the group 3was co-administratedwith single ITsilica and Vitamin D (20mg/kg/day) daily for a period of 90 days. The rats of group 4 received Vitamin D daily for a period of 90 days. Results: Silica significantly increased serum and lung total Oxidant Status (TOS). Meanwhile, silica reduced serum and lung total antioxidant capacity (TAC), GSH and tumor necrosis factor-a (TNF-a). Vitamin D treatment meaningfully reversed oxidative stress, antioxidants status and inflammatory response. Also, Vitamin D improved histopathological changes caused by silica. Conclusion: These findings indicate that Vitamin D exerts protective effects against silica-induced lung injury. It seems that Vitamin D has potential use as a therapeutic object for silica induced lung injure.