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Attract-and-kill: a new strategy for the management of the potato tuber moths Phthorimaea operculella (Zeller) and Symmetrischema tangolias (Gyen) in potato: laboratory experiments towards optimising pheromone and insecticide concentration
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Effects of exercise training on quadriceps muscle gene expression in chronic obstructive pulmonary disease
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인터넷을 활용한 국어과 쓰기 지도의 수업모형 구안과 그 효과
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DYNAMIC CAVITY CONTROL IN A SHORT PULSE FREE-ELECTRON LASER OSCILLATOR
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호흡 기능 향상을 위한 들숨근 강화 훈련 방법 : 위팔운동을 동반한 가로막 호흡과 파워브리드 호흡의 효과 비교
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Population structure and mating system of Ascochyta rabiei in Tunisia: evidence for the recent introduction of mating type 2
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- 저자 : Danny Wong (검색결과 4 건)
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Danny Wong,Changyong Yim,Simon S. Park 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.7 No.2
Novel green electrodes were fabricated through the combination of cellulose nanocrystals (CNC), graphene nanoplatelets (GNP) and copper precursors. Electrodes were produced by a hybrid manufacturing process that included vacuum filtration, intensive pulsed light (IPL) sintering, mechanical hot pressing and heat treatment to reduce the number of junctions and flatten the components into a parallel arrangement. Copper provides excellent electrical conductivity and cost efficiency, but it can be easily oxidized. CNC is a renewable material that acts as a strong binder, allowing the compaction of the electrodes and providing a surface for copper ions to be adsorbed. GNP prevents copper oxidation and acts as conductive bridges. This combination of processes and materials yielded decreases in electrical resistance, even after 5 days of heat treatment at 175 °C that would typically cause oxidation. At this temperature, carbonization of CNC began to occur. After applying a two percent strain to the electrodes, high CNC concentration electrodes maintained a similar electrical performance, whereas low CNC concentration electrodes exhibited a significant reduction in electrical conductivity. The ability to withstand elevated temperatures for long durations and external strains make the nanocomposite electrodes attractive for various applications such as electrodes, electrical devices and sensors
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Flexibility Enhancements of Hybrid Copper Inks with Cellulose Nanocrystals
Lei Liu,Danny Wong,Jihyun Lee,Simon S. Park 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.6
Increasingly, copper nanopowders are commonly used in conductive inks due to their cost-efficiency compared to silver or gold and excellent electrical conductivity. One of the challenges associated with copper inks is oxidation and to address, we have developed a hybrid copper-based ink by removing the oxide layer of copper powders and coat the powders with a silver shell to protect from oxidation. Despite the advances, the inks are prone to fatigue failures when the ink films are repeatedly bent or stretched. In order to overcome this challenge, we proposed to integrate cellulose nanocrystals (CNC) with the copper-based ink on a polymer substrate and use a sintering process based on intense pulsed light in an argon atmosphere. Sintering in argon gas environment improved in electrical conductivity that may be the result of the partial carbonization of the CNC rather than combustion. It has also been experimentally determined that CNC improved adhesion strength of the copper ink fi lm. Moreover, the addition of CNC also reduced the damage caused by bending and stretching. The ink fi lm containing 10% CNC increased the electrical resistance by only 3.82 times after 600 bending cycles versus the resistance increased by 34.4 times without CNC. Under the 30% strain of stretching, the change in resistance of the ink fi lm containing 10% CNC was 1.75 times lower than without CNC. It was observed through microscopy techniques that the presence of CNC reduced the formation of cracks by enhancing mechanical strength.
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Lung-Yi Mak,Danny Wong,Alison Kuchta,Martina Hilfiker,Aaron Hamilton,Ning Chow,Xianhua Mao,Wai Kay Seto,Man Fung Yuen 대한간학회 2023 Clinical and Molecular Hepatology(대한간학회지) Vol.29 No.1
Background/Aims: We investigated the dynamics of serum HBV pre-genomic RNA (pgRNA) and hepatitis B core-related antigen (HBcrAg) in patients receiving nucleos(t)ide analogues (NAs) and their predictability for favourable suppression of serum hepatitis B surface antigen (HBsAg). Methods: Serum viral biomarkers were measured at baseline, weeks 4, 12, 24, 36, and 48 of treatment. Patients were followed up thereafter and serum HBsAg level was measured at end of follow-up (EOFU). Favourable HBsAg response (FHR) was defined as ≤100 IU/mL or HBsAg seroclearance upon EOFU. Results: Twenty-eight hepatitis B e antigen (HBeAg)-positive and 36 HBeAg-negative patients (median, 38.2 years old; 71.9% male) were recruited with median follow-up duration of 17.1 years (interquartile range, 12.8–18.2). For the entire cohort, 22/64 (34.4%) achieved FHR. For HBeAg-positive patients, serum HBV pgRNA decline at week 4 was significantly greater for patients with FHR compared to non-FHR (5.49 vs. 4.32 log copies/mL, respectively; P=0.016). The area under the receiver-operating-characteristic curve (AUROC) for week 4 HBV pgRNA reduction to predict FHR in HBeAg-positive patients was 0.825 (95% confidence interval [CI], 0.661–0.989). For HBeAg-negative patients, instead of increase in serum HBcrAg in non-FHR patients, FHR patients had median reduction in HBcrAg at week 4 (increment of 1.75 vs. reduction of 2.98 log U/mL; P=0.023). The AUROC for week 4 change of HBcrAg to predict FHR in HBeAg-negative patients was 0.789 (95% CI, 0.596–0.982). Conclusions: Early on-treatment changes of serum HBV pgRNA and HBcrAg at 4 weeks predict HBsAg seroclearance or ≤100 IU/mL in NA-treated CHB patients upon long-term FU.
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Lung-Yi Mak,Kwan-Lung Ko,Wai-Pan To,Danny Ka-Ho Wong,Wai-Kay Seto,James Fung,Man-Fung Yuen 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.5
Serum hepatitis B core-related antigen (HBcrAg) was shown to predict the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients undergoing treatment. We investigated the longitudinal profile of HBcrAg in entecavir (ETV)-treated CHB patients with subsequent HCC development. We identified HCC cases diagnosed at ≥1 year after ETV initiation. CHB patients without HCC (matched for age, sex, cirrhosis status, baseline hepatitis B virus [HBV] DNA level, and ETV treatment duration) were identified as controls at an HCC:non-HCC ratio of 1:2. Serum samples were retrieved at baseline (ETV initiation) and at 3 and 5 years of ETV therapy for HBcrAg measurement (log IU/mL). In total, 180 patients (60 HCC patients matched with 120 CHB patients without HCC; median age, 56.5 years; 80.6% male; baseline HBV DNA, 5.9 log IU/mL; median follow-up, 6.8 years) were recruited. The median time from ETV initiation to HCC development was 3.2 years. HBcrAg levels were higher in HCC cases than in controls at all three time points: 5.69 log IU/ mL versus 5.02 log IU/mL (p=0.025), 4.23 log IU/mL versus 3.36 log IU/mL (p=0.007), and 3.86 log IU/mL versus 3.36 log IU/mL (p=0.009), respectively. ETV led to similar rates of decline in HBcrAg from baseline to 3 years in both groups (0.34 log IU/mL/year vs 0.39 log IU/mL/year, p=0.774), although the decline from 3 to 5 years was slower in the non- HCC group (0.05 log IU/mL/year) than in the HCC group (0.09 log IU/mL/year, p=0.055). ETV time-dependently reduced HBcrAg in HCC and non-HCC patients. HBcrAg interpretation should consider the antiviral treatment duration.
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