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Commissioning Status of the Linac for the Facility for Rare Isotope Beams
Lidia S.,Ao H.,Barnes B.,Bennett R.,Bernal-Ruiz E.,Bollen G.,Brandon J.,Bull B.,Bultman N.,Casagrande F.,Chabot D.,Cogan S.,Compton C.,Davidson K.,Daykin E.,Georgiobani D.,Gibson P.,Grender I.,Kim S.- 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.77 No.5
The Facility for Rare Isotope Beams will be completed in late 2021. We report here on the current efforts to commission the first stages of the 200-MeV/u superconducting, continuous wave heavy-ion linac. The statuses of the cryogenic plant and its distribution system, the accelerator cryomodule commissioning and operations, the ion source and front end transport development, the radio-frequency quadrupole commissioning, and thenbeam dynamics development to support high-power operation are reviewed. Plans for commissioning the remainder of the linac systems are presented.
Yoo, Yun Joo,Kim, Sun Ah,Bull, Shelley B. Hindawi Publishing Corporation 2015 BioMed research international Vol.2015 No.-
<P>Gene-based analysis of multiple single nucleotide polymorphisms (SNPs) in a gene region is an alternative to single SNP analysis. The multi-bin linear combination test (MLC) proposed in previous studies utilizes the correlation among SNPs within a gene to construct a gene-based global test. SNPs are partitioned into clusters of highly correlated SNPs, and the MLC test statistic quadratically combines linear combination statistics constructed for each cluster. The test has degrees of freedom equal to the number of clusters and can be more powerful than a fully quadratic or fully linear test statistic. In this study, we develop a new SNP clustering algorithm designed to find cliques, which are complete subnetworks of SNPs with all pairwise correlations above a threshold. We evaluate the performance of the MLC test using the clique-based CLQ algorithm versus using the tag-SNP-based LDSelect algorithm. In our numerical power calculations we observed that the two clustering algorithms produce identical clusters about 40~60% of the time, yielding similar power on average. However, because the CLQ algorithm tends to produce smaller clusters with stronger positive correlation, the MLC test is less likely to be affected by the occurrence of opposing signs in the individual SNP effect coefficients.</P>
Roh, H.,Uguru, G. C.,Ko, H.-J.,Kim, S.,Kim, B.-Y.,Goodfellow, M.,Bull, A. T.,Kim, K. H.,Bibb, M. J.,Choi, I.-G.,Stach, J. E. M. American Society for Microbiology 2011 Journal of Bacteriology Vol.193 No.13
<P>Verrucosispora maris AB-18-032 is a marine actinomycete that produces atrop-abyssomicin C and proximicin A, both of which have novel structures and modes of action. In order to understand the biosynthesis of these compounds, to identify further biosynthetic potential, and to facilitate rational improvement of secondary metabolite titers, we have sequenced the complete 6.7-Mb genome of Verrucosispora maris AB-18-032.</P>