Clinical Outcomes of Transcatheter Arterial Embolization after Failed Endoscopic Intervention for Acute Non-Variceal Bleeding Associated with Benign Upper Gastrointestinal Diseases

Sang Yoon Kim,Su Jin Kim,Ayoung Lee,Kichul Yoon,Jun Young Park,Ju Yup Lee,Jae Myung Park 대한상부위장관ㆍ헬리코박터학회 2023 Korean Journal of Helicobacter Upper Gastrointesti Vol.23 No.1

Background/Aims: Transcatheter arterial embolization (TAE) is useful for management of uncontrolled upper gastrointestinal (UGI) bleeding. We investigated clinical outcomes of TAE for non-variceal bleeding from benign UGI diseases uncontrolled with endoscopic intervention. Methods: This retrospective study performed between 2017 and 2021 across four South Korean hospitals. Ninety-two patients (72 men, 20 women) who underwent angiography were included after the failure of endoscopic intervention for benign UGI disease- induced acute non-variceal bleeding. We investigated the factors associated with endoscopic hemostasis failure, the technical success rate of TAE, and post-TAE 30-day rebleeding and mortality rates. Results: The stomach (52/92, 56.5%) and duodenum (40/92, 43.5%) were the most common sites of bleeding. Failure of endoscopic procedures was attributable to peptic ulcer disease (81/92, 88.0%), followed by pseudo-aneurysm (5/92, 5.4%), and angiodysplasia (2/92, 2.2%). Massive bleeding that interfered with optimal visualization of the endoscopic field was the most common indication for TAE both in the stomach (22/52, 42.3%) and duodenum (14/40, 35.0%). Targeted TAE, empirical TAE, and exclusive arteriography were performed in 77 (83.7%), nine (9.8%), and six patients (6.5%), respectively. The technical success rate, the post-TAE 30-day rebleeding rate, and the overall mortality rate were 100%, 22.1%, and 5.8%, respectively. On multivariate analysis, coagulopathy (OR, 5.66; 95% CI, 1.71~18.74; P=0.005) and empirical embolization (OR, 5.71; 95% CI, 1.14~28.65; P=0.034) were independent risk factors for post-TAE 30-day rebleeding episodes. Conclusions: TAE may be useful for acute non-variceal UGI bleeding. Targeted embolization and correction of coagulopathy can improve clinical outcomes.

방재기술 현황분석 및 방재기술 유형에 따른 해외이전 방안수립에 대한 연구

김아영(Kim, Ayoung),윤소연(Yoon, Soyeon),손홍규(Sohn, Hong Gyoo),윤동근(Yoon, Dong Keun) 대한공간정보학회 2017 한국지형공간정보학회 학술대회 Vol.2017 No.5

본 연구는 국내 방재기술의 발전방안을 시장확대, 국제협력 강화 측면으로 모색하는 연구로써, 방재기술의 현황을 분석하고 설문조사를 통해 경쟁력을 보유한 기술을 도출하였다. 방재기술 이전을 위한 상대국가의 수요파악을 위해 국가협력전략(CPS), 국가개발계획, 재난피해 및 특성 등을 검토하였다. 시범사업 대상국가로 선정된 인도네시아의 방재분야 수요분석을 기반으로 기술매칭을 진행하였다. This study aims to develop strategies for disaster prevention technologies in Korea in terms of market expansion and strengthening international cooperation. To analyze demands for disaster prevention technologies in developing countries, Country Partnership Strategy (CPS), National Development Plans, and disaster types and damages of countries were reviewed. Also, a technology matching was proceeded based on the analysis on disaster prevention technology demands in Indonesia.

태양광 발전소의 음영 분석과 발전량 상관관계 분석

오원욱(Oh Wonwook),전성근(Jeon Seonggeun),윤아영(Yoon Ayoung),김대장(Yoon Ayoung),최훈주(Choi hoonjoo) 한국태양에너지학회 2021 한국태양에너지학회 논문집 Vol.41 No.2

A photovoltaic (PV) string consists of PV modules that are connected in series. When partial shading occurs in the PV modules, the total PV string current is lowered. When the partial shading becomes severe, the bypass diode operates. Most PV systems are exposed to partial shading by nearby terrain, rather than an actual shaded flat environment. In this study, shading analysis was performed at 19 points of a 33.2 kWp solar power plant installed on the roof of a building, and the shaded irradiance ratio at the PV module location was estimated using this result. We compared the results of the performance ratio monitored for one year. As a result, the expected output ratio of the shading analysis compared to normal was found to be 89.6%, and the annual performance ratio was 90.2%.

Is Helicobacter pylori Infection Associated With Ulcerative Colitis Activity?

Ayoung Lee,Choe Jung Wan,Sung Woo Jung,Jae Youn Park,Ik Yoon,Seung Young Kim 대한상부위장관ㆍ헬리코박터학회 2024 Korean Journal of Helicobacter Upper Gastrointesti Vol.24 No.1

Objectives: Epidemiological studies have shown an inverse association between Helicobacter pylori infection and ulcerative colitis (UC). In this study, we investigated the protective effects of H. pylori infection on the severity of UC. Methods: This single-center study included 316 patients with newly diagnosed UC based on findings of colonoscopy and upper endoscopy for H. pylori evaluation between January 1994 and December 2015. Patients’ medical records were retrospectively reviewed, and severity of UC was assessed based on endoscopic findings, clinical symptoms, treatment regimens, and Mayo scores. Results: The prevalence of H. pylori infection in patients with UC was 74/316 (23.4%). Based on upper endoscopic findings, the percentage of patients with duodenal ulcers was significantly higher in the H. pylori positive group than that in the H. pylori negative group (27.0% vs. 11.6%, p=0.022). Disease extent and endoscopic severity showed no significant intergroup difference (p=0.765 and p=0.803, respectively). Endoscopic severity was unaffected by the H. pylori infection status, based on the extent of endoscopically documented disease and endoscopic findings. Furthermore, UC-related symptom severity assessed on the basis of stool frequency, rectal bleeding severity, and rate of admission necessitated by UC aggravation was not associated with H. pylori infection (p=0.185, 0.144, and 0.182, respectively). Use of steroids as induction therapy for severe UC did not differ with regard to H. pylori infection (p=0.327). No intergroup difference was observed in disease severity of UC classified using the Mayo score (p=0.323). Conclusions: H. pylori infection was detected in approximately 25.0% of patients with UC. However, the H. pylori infection status was not associated with the severity of UC based on endoscopic disease activity, patients’ symptoms, steroid use, or the Mayo clinic score.

가토의 위장관 및 담췌관에서의 내시경하 봉합사 안전성 및 유해성 검증

채윤석(Yoon-Seok Chae),최진섭(Jin Sub Choi),박영년(Ayoung-Nyun Park),김경식(Kyung-Sik Kim),이우정(Woo-Jung Lee),김병로(Byong-Ro Kim) 한국간담췌외과학회 2001 한국간담췌외과학회지 Vol.5 No.1

⁶⁴Cu-Labeled Repebody Molecules for Imaging of Epidermal Growth Factor Receptor–Expressing Tumors

Pyo, Ayoung,Yun, Misun,Kim, Hyeon Sik,Kim, Tae-Yoon,Lee, Joong-jae,Kim, Jung Young,Lee, Sunwoo,Kwon, Seong Young,Bom, Hee-Seung,Kim, Hak-Sung,Kim, Dong-Yeon,Min, Jung-Joon Society of Nuclear Medicine 2018 The Journal of nuclear medicine Vol.59 No.2

<P>The epidermal growth factor receptor (EGFR) is a member of the erbB family of receptors and is overexpressed in many tumor types. A repebody is a newly designed nonantibody protein scaffold for tumor targeting that contains leucine-rich repeat modules. In this study, 3 <SUP>64</SUP>Cu-labeled anti-EGFR repebodies with different chelators were synthesized, and their biologic characteristics were assessed in cultured cells and tumor-bearing mice. <B>Methods:</B> Repebodies were synthesized with the chelators 2-(<I>p</I>-isothiocyanatobenzyl)-1,4,7-triazacyclononane-<I>N,N′,N,″-</I>triacetic acid trihydrochloride ([<I>p</I>-SCN-Bn]-NOTA), 2,2′,2″-(10-(2-(2,5-dioxopyrrolidin-1-yloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid (DOTA-<I>N</I>-hydroxysuccinimide ester), or 1-(<I>p</I>-isothiocyanatobenzyl)diethylenetriamine pentaacetic acid trihydrochloride ([<I>p</I>-SCN-Bn]-DTPA) in 1.0 M NaHCO<SUB>3</SUB> buffer (pH 9.2) for 24 h. Purified NOTA-, DOTA-, and DTPA-conjugated repebody were radiolabeled with <SUP>64</SUP>Cu in 0.1 M NH<SUB>4</SUB>OAc buffer (pH 5.5). To compare the EGFR-binding affinities of the repebodies, cellular uptake studies were performed with the human non–small cell lung cancer cell line H1650 (high expression of EGFR) and the human colon adenocarcinoma cell line SW620 (low expression of EGFR). Biodistribution and small-animal PET imaging studies were performed using H1650 tumor–bearing mice. <B>Results:</B> Radiochemical yields of the <SUP>64</SUP>Cu-labeled repebodies were approximately 70%–80%. Cellular uptake of the NOTA-, DOTA-, and DTPA-repebodies was over 4-fold higher in H1650 cells than in SW620 cells at 1 h. The 3 repebodies had accumulated specifically in H1650 tumor–bearing nude mice by 1 h after intravenous injection and were retained for over 24 h, as measured by the percentage injected dose per gram of tissue (%ID/g). Tumor uptake of all repebodies increased from 1 to 6 h (at 1 h, 6.28, 8.46, and 6.91 %ID/g for NOTA-, DOTA-, and DTPA-repebody, respectively; at 6 h, 9.4, 8.28, and 10.1 %ID/g, respectively). H1650 tumors were clearly visible after injection of each repebody, with high tumor-to-background ratios (at 1 h, 3.43, 4.89, and 2.38 for NOTA-, DOTA-, and DTPA-repebody, respectively; at 6 h, 3.05, 4.36, and 2.08; at 24 h, 3.81, 4.58, and 2.86). <B>Conclusion:</B> The 3 <SUP>64</SUP>Cu-repebody complexes demonstrated specific and rapid uptake in EGFR-expressing tumors within 1 h and may have potential as novel EGFR imaging agents for PET.</P>

5W/m·K급 방열소재가 적용된 프로젝션 타입 클러스터의 열적 특성 및 시인성에 관한 연구

오미혜(Meehye OH),김아영(Ayoung Kim),장은진(Eunjin Jang),윤여성(Yeoseung Yoon),오석철(Suckchul Oh),김문수(Moonsoo Kim) 한국자동차공학회 2017 한국자동차공학회 학술대회 및 전시회 Vol.2017 No.11

인스타그램 해시태그 기반의 전시관람경험에 대한 반응 분석

박지현(Jihyun Park),석아영(Ayoung Seok),윤영준(Youngjun Yoon),이보아(Bo-A Rhee) 한국컴퓨터정보학회 2018 한국컴퓨터정보학회 학술발표논문집 Vol.26 No.2

박물관 3.0시대의 도래와 함께 박물관 경영 측면에서 빅데이터 분석, 그리고 공유와 개방의 관점 및 커뮤니케이션 플랫폼과 마케팅 도구로써 소셜 미디어의 영향력이 증대되고 있다. 모바일 애플리케이션이나 비콘에 의존했던기존의 박물관 빅데이터 분석과는 달리, 본 연구에서는 전시에 대한 인스타그램의 해시태그를 분석함으로써, 관람객 분석도구로써 인스타그램 해시태그의 효용성과 가치를 입증하는데 목적을 두고 있다. 이를 위해 최근 2년 동안 국내에서 개최된 다섯 개의 전시의 인스타그램 해시태그를 수집 및 시각화했다. 그 결과, 모든 전시의 인스타그램의 해시태그는 전시명, 전시장소, 전시회, 지역명, 작가명에 집중되었다. 결론적으로 인스타그램의 해시태그는 전시관람 경험에 대한 분석을 위한 빅데이터로 사용하는 것이 부적합했다. 또한 관람객 개발을 위한 도구로써 인스타그램 해시태그의 효용성과 가치는 입증되지 못한 반면, 노출형에 해당하는 해시태그의 정보 확산에 대한 잠재력은 확인되었다.

프랜차이즈 커피 전문점의 프로모션 종류가 고객 만족도와 행동의도에 미치는 영향

남아영,윤지영,Nam, Ayoung,Yoon, Jiyoung 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.1

This research was conducted to examine coffee shop customers' preference and satisfaction by different types of promotion. Research samples ware adults with experience of any form of coffee shop promotion (n=209). Descriptive statistics, Chi-square, t-test and one-way ANOVA were used to analyze the relations among variables. Results showed that 'free coupon' was the most preferred ones. SNS was the most frequently used search method for coffee shop coupon promotion information. The most preferred event promotion was 'freebies', and preference levels were significantly different by age and employment status. 'Barista experience' was ranked highest in preference among cultural experience events. Drinking coffee was the most important purpose of visiting coffee shops, especially among unemployed, twenties, and women respondents. Coupon was evaluated the highest in usefulness and satisfaction among the three promotion methods. Event and cultural experience were preferred more by respondents in their twenties than those in their thirties. Results indicated that all promotion strategies are effective for increasing customer satisfaction and for inducing revisit. Findings also showed that preference for promotion was affected by customer characteristics such as age and gender. Therefore, coffee shops should consider using the most effective and attractive promotion strategy for their target market, while maintaining a consistent service quality level to fulfill customer expectation.

An Analysis of Instagram Hashtags Related to the Exhibitions in Korea

Jihyun Park(박지현),Ayoung Seok(석아영),Youngjun Yoon(윤영준),Boa Rhee(이보아) 한국컴퓨터정보학회 2019 韓國컴퓨터情報學會論文誌 Vol.24 No.3

The purpose of this study is to analyze the characteristics and meanings of Instagram hashtags related to the exhibitions as a online communication platform of museums. At the same time, it focuses on efficiency of hashtags as a reference framework of inferring viewing experiences. We collect and visualize Instagram hashtags of exhibitions held in Korea for the past two years including ‘Paper Present (2017)’, ‘YOUTH (2017)’, ‘Monet, Draw Light Exhibition (2018)’, ‘Van Gogh Inside (2016)’, ‘Drawn by the Wind: Shin yun-bok & Jeong Seon’. To sum up, significant data related to viewing experiences are not derived, and hashtags as a reference framework of inferring viewing experiences are turned out to be inefficient. Meanwhile, we conclude that potential for distributing information about the exhibitions is inherent in hashtags. In terms of informational characteristics, we notice that the influence of hashtags related to regional information is presented more than the response toward the viewing experiences. This result shows that Instagram users in the exhibitions are worthy of place making rather than viewing experiences.