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Shelvin Kumar Vadi,Devendra Kumar Chouhan,Arun Kumar Reddy Gorla,Jaya Shukla,Ashwani Sood,Bhagwant Rai Mittal 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.3
Primary synovial osteochondromatosis (PSOC) is a rare but clinically significant cause of morbidity especially in the male population. Surgery is the primary treatment of choice, but the recurrence rate is reported to be high. Moreover, the presence of widespread loose bodies makes it a cumbersome procedure. The complete removal of the disease is tough at times and results in early recurrence. Radiosynovectomy is an established technique for treating various joint arthropathies. The role of radiosynovectomy in case of PSOC has not yet been explored. This case report described the case of a young male with PSOC of the knee joint who was treated with radiosynovectomy for pain relief. The patient reported complete relief from the pain along with significant improvement in joint mobility. The post-therapy three-phase bone scan also validated the reduction in joint inflammation. The patient was taken for surgical removal of the redundant loose bodies after a significant improvement in the pain and reduction in inflammation. Post-therapy radiation fibrosis of the synovium also helped in the en bloc removal of the disease. The role of radiosynovectomy in PSOC needs to be further explored concerning its potential role as an adjuvant to surgical procedures.
Jain Tarun Kumar,Singh Harmandeep,Kumar Rajender,Bal Amanjit,Sood Ashwani,Mittal Bhagwant Rai 대한핵의학회 2020 핵의학 분자영상 Vol.54 No.5
Pulmonary blastoma (PB) is a rare thoracic malignancy and preoperative diagnosis is challenging. A young man presented with dyspnea and chest pain for 3–4 months and chest-computed tomography (CT) revealed large mass in the left lung upper lobe and pleural effusion. Repeated CT-guided fine-needle aspiration cytology from the lesion and pleural fluid aspiration was negative for malignancy. F-18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) revealed heterogeneous tracer avidity in left lung mass with areas of necrosis. Real-time PET-CT-guided biopsy from metabolically active component of the lesion revealed biphasic PB on histopathology.
Niti Pathak,Ashwani Kumar Rai,Supradip Saha,Suresh Walia,Soumitra Kumar Sen,Kangila Venkataraman Bhat 한국작물학회 2014 Journal of crop science and biotechnology Vol.17 No.3
Sesame (Sesamum indicum L.) is one of the oldest oilseed crops grown in India and worldwide. This oilseed crop has high nutritionalvalue due to the presence of antioxidants such as lignans and tocopherols. Screening of oilseed germplasm for important nutritionalattributes is of prime importance in quality breeding programs. In the present study, the content of lignans (sesamin andsesamolin) and tocopherol homologues (α-, γ -, and δ-tocopherol) was determined using reverse phase HPLC (RP-HPLC) in 143sesame lines collected from diverse agro-ecological zones of India. Exploitable levels of sesamin, sesamolin, γ-, and δ-tocopherolwas observed in the studied sesame lines. Sesamum indicum cultivar CO 1, introgressed line MKN 9, and Sesamum malabaricumshowed high values for sesamin. Exotic and indigenous accessions of S. indicum (EC 542283 and IC 132176, IC 204681, IC 204773)showed high sesamolin contents. Cultivars, AKT 64, AKT 101, Phule til 1, and Tapi A showed high values for γ - and δ-tocopherol. The average content of sesamin and sesamolin was 0.86 and 0.50 mg g-1 seed, respectively. The average tocopherol content (292 μgg-1 seed) found in this study indicates the presence of a high amount of tocopherol in Indian sesame germplasm. Superior genotypesof sesame reported in this study could be utilized in sesame breeding programs for enhancing oil yield and nutritional attributes
Venkata Subramanian Krishnaraju,Kumar Rajender,Sood Ashwani,Jaya Shukla,Karthikeyan Subramanian,Nandita Kakkar,Naresh Panda,Mittal Bhagwant Rai 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.3
Chondrosarcoma is a cartilaginous tumor of mesenchymal origin. The histology and grade of the tumor determine the chances of relapse and survival. These tumors usually respond poorly to chemo-radiotherapy in cases of non-resectable and recurrent disease. 18F-FDG PET/CT has been used in evaluation of recurrence. However, these tumors show only mild to moderate FDG avidity due to their lower mitotic activity and large acellular matrix. These tumors are known to have a high degree of angiogenesis, especially in those of higher grade. We present a case of a 53-year-old man with grade II chondrosarcoma of the left femur showing only mild avidity on 18F-FDG PET/CT but showing moderate to intense tracer avidity on 68Ga-DOTA-RGD2 PET/CT. This may enable the use of angiogenesis-targeted positron and beta-emitting radiopharmaceuticals as a potentially new theranostic alternative treatment in cases of refractory metastatic chondrosarcoma.