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        Study on Morphology, Thermal and Rheological Properties of Polypropylene/Poly(trimethylene terephthalate) Polyblend Fibers

        Mohammad Reza Habibolah Zargar,Atefeh Ghaffarian,Amin Ebrahimzade,Ahmad Mousavi Shoushtari 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12

        In the present work, a systematic study of the variables affecting the production of polypropylene (PP)/poly(trimethylene terephthalate) (PTT) blend fibers such as the PTT and PP-g-MA compatibleizer ratios and take-up speed inthe melt-spinning process was done. Modeling of the melt-spinning process was carried out by using a statistical approachbased on response surface methodology (RSM) to achieve a mathematical model. The formation of the fibrillar structuresthrough different steps of fiber formation was confirmed by scanning electron microscopy (SEM). The lowest mean diameterof nano-fibrils was achieved to be 63 nm, for the hot-drawn fibers consisting of 10 wt.% of PTT. The synergetic effect of thepresence of PTT dispersed phase on the mechanical properties of PP fibers as a matrix was verified by observing a positivedeviation from the blends linear law for the samples with 10 wt.% of PTT. The rheological evaluations suggested theformation of a fibril structure in the blends. The X-ray diffraction spectroscopy and DSC results showed that the presence ofPTT significantly influenced the crystallinity of PP. Moreover, results indicated that the average crystal size of the PP matrixphase was affected by the presence of the PTT dispersed phase, which also confirmed its nucleating effect in the blend.

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        Technical Advances to Accelerate Modular Type I Polyketide Synthase Engineering towards a Retro-biosynthetic Platform

        Bo Pang,Luis E. Valencia,Jessica Wang,Yao Wan,Ravi Lal,Amin Zargar,Jay D. Keasling 한국생물공학회 2019 Biotechnology and Bioprocess Engineering Vol.24 No.3

        Modular type I polyketide synthases (PKSs) are multifunctional proteins that are comprised of individual domains organized into modules. These modules act together to assemble complex polyketides from acyl-CoA substrates in a linear fashion. This assembly-line enzymology makes engineered PKSs a potential retrobiosynthetic platform to produce fuels, commodity chemicals, speciality chemicals, and pharmaceuticals in various host microorganisms, including bacteria and fungi. However, the realization of this potential is restricted by practical difficulties in strain engineering, protein overexpression, and titer/yield optimization. These challenges are becoming more possible to overcome due to technical advances in PKS design, engineered heterologous hosts, DNA synthesis and assembly, PKS heterologous expression, and analytical methodology. In this review, we highlight these technical advances in PKS engineering and provide practical considerations thereof.

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