Are Mentalizing Abilities and Insight Related to the Severity of Obsessive-Compulsive Disorder

Leman İnanç,Merih Altıntaş 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.9

Objective The aim of this study is to investigate whether insight and mentalizing abilities are related to the severity of Obsessive Compulsive Disorder (OCD) in treatment resistant OCD. We look at the association between treatment resistance, insight, and mentalizing ability. Methods The study was conducted with 71 OCD patients; 30 of them met the criteria for treatment resistant OCD, whereas the other 41 (57.7%) were labeled as responder group. All patients were assessed with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Reading the Mind in the Eyes Test (RMET), Brown Assessment of Beliefs Scale (BABS), Mini International Neuropsychiatric Interview, Beck Depression Inventory, and Beck Anxiety Inventory. Results The resistant group received higher depression and anxiety mean scores and had significantly longer illness duration. The RMET score was significantly higher for responders. The Y-BOCS insight score and the BABS score were significantly higher for the resistant group. BABS scores were negatively correlated with RMET total scores. RMET scores were found to be significant predictor of insight even when other potential factors were controlled for. Conclusion Results suggest that better mentalizing abilities may be a predictor of better treatment outcome in patients with OCD.

Combined effect of phosphorus, magnesium, yeast extract on lipid productivity of Yarrowia lipolytica grown with molasses

Ece Polat,Gizem Yörücü,Mahmut Altınbaş 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.10

Inadequate global fossil fuel reserves have forced researchers to investigate alternative fuel sources, and oleaginous microorganisms have attracted attention with their potential. Since high lipid production yield is an important criterion for suitable fuel production, in this study an oleaginous yeast, Yarrowia lipolytica, was selected and the lipid and biomass productivity under molasses (M20) substrate and nutrient supplementation was investigated. The effect of phosphorus as dipotassium hydrogen phosphate (K2HPO4), magnesium as magnesium sulphate (MgSO4), and yeast extract supplementation to molasses (M20) were evaluated individually and in combination. In addition, two quadratic models, using Box-Wilson central composite design, were used to correlate the phosphorus, magnesium and yeast extract concentrations that would achieve the highest biomass and lipid productivity. The study has shown that molasses (M20) supplemented with 336mg/L K2HPO4, 0.17 g/L MgSO4 and 4.54 g/L yeast extract had the highest biomass productivity (80.7mg/L/hour) and the highest lipid productivity (28.3mg/L/hour). These productivity results were 1.44-fold and 2.42-fold higher than those of yeast extract-peptone-dextrose (YPD) broth, respectively. With enhanced biomass and lipid productivity, Yarrowia lipolytica can thus be used effectively in the fermentation industry.

A Report of Rabbit Syndrome Who Benefited from Sigma 1 Agonist Fluvoxamine

Yakup Albayrak,Murat Beyazyüz,Özlem Abbak,Ece Altındağ 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.1

Rabbit Syndrome is an uncommon side effect of antipsychotic treatment. Although it is usually associated with typical antipsychotics, it can also be related to atypical antipsychotics. Anticholinergics are the most accepted treatment approach in treating Rabbit Syndrome. Fluvoxamine is a member of selective serotonin reuptake inhibitors and it is a potent agonist of sigma 1 receptors. In this article, we report a Rabbit Syndrome case who has benefited from fluvoxamine, in terms of both depressive disorder and Rabbit Syndrome; and present the data on the effects of sigma 1 agonist fluvoxamine on numerous movement disorders.

Effi cacy of the Combination of Tetracycline, Amoxicillin, and Lansoprazole in the Eradication of Helicobacter pylori in Treatment-Naïve Patients and in Patients Who Are Not Responsive to Clarithromycin-Based Regimens: A Pilot Study

Mesut Sezikli,Züleyha Akkan Çetinkaya,Fatih Güzelbulut,Atakan Yeşil,Mustafa Erhan Altınöz,Nuriye Ulu,Ayşe Oya Övünç Kurdaş 거트앤리버 소화기연관학회협의회 2012 Gut and Liver Vol.6 No.1

Background/Aims: The aim of this study was to evaluate the eradication rate of a triple therapy regimen that included a proton pump inhibitor, amoxicillin, and tetracycline instead of clarithromycin in treatment-naïve patients and in patients who did not respond to standard triple therapy. Methods: This study included 110 patients infected with Helicobacter pylori. Patients in groups A and B were treatment-naïve, and those in group C were not responsive to previous standard triple therapy. Patients in group A (n=40) received lansoprazole 30 mg b.i.d., amoxicillin 1,000 mg b.i.d., and clarithromycin 500 mg b.i.d. for 14 days. Patients in groups B (n=40) and C (n=30) received lansoprazole 30 mg b.i.d., amoxicillin 1,000 mg b.i.d., and tetracycline 500 mg q.i.d. for 14 days. Results: In group A, eradication was achieved in 18 (45%) of the 40 patients included in the intention-to-treat (ITT) analysis and in 18 (47.4%) of the 38 patients included in the per-protocol (PP) analysis. In group B, eradication was achieved in 15 (37.5%) of the 40 patients included in the ITT analysis and in 15 (39.3%) of the 38 patients included in the PP analysis. In group C, eradication was achieved in 14 (46.6%) of the 30 patients included in the ITT analysis and in 14 (43.8%) of the 29 patients included in the PP analysis. There was no statistically signifi cant difference among the 3 groups with regard to eradication rates (p>0.05). Conclusions: Despite the low rate of resistance to tetracycline, the combination of lansoprazole, amoxicillin, and tetracycline instead of clarithromycin is not a good option for the eradication of H. pylori.

No Association between Polymorphisms of Vitamin D and Oxytocin Receptor Genes and Autistic Spectrum Disorder in a Sample of Turkish Children

Sevcan Tug Bozdogan,Meryem Ozlem Kutuk,Evren Tufan,Zuhal Altıntaş,Gülhan Orekici Temel,Fevziye Toros 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.4

Objective: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social skills and communication with repetitive behaviors. Etiology is still unclear although it is thought to develop with interaction of genes and environmental factors. Oxytocin has extensive effects on intrauterine brain development. Vitamin D, affects neural development and differentiation and contributes to the regulation of around 900 genes including oxytocin receptor gene. In the present study, the contribution of D vitamin receptor and oxytocin receptor gene polymorphisms in the development of ASD in Turkish community was investigated. To our knowledge, this is the first study examining these two associated genes together in the literature. Methods: Eighty-five patients diagnosed with ASD according to DSM-5 who were referred to outpatient clinics of Child and Adolescent Psychiatry of Başkent University and Mersin University and 52 healthy, age and gender-matched controls were included in the present study. Vitamin D receptor gene rs731236 (Taq1), rs2228570 (Fok1), rs1544410 (Bsm1), rs7975232 (Apa1) polymorphisms and oxytocin receptor gene rs1042778 and rs2268493 polymorphisms were investigated using real time polymerase chain reaction method. Results: No significant difference between groups in terms of distribution of genotype and alleles in each of polymorphisms for these genes could be found. Conclusion: Knowledge of genes and polymorphisms associated with the development of ASD may be beneficial for early diagnosis and future treatment. Further studies with larger populations are required to demonstrate molecular pathways which may play part in the development of ASD in Turkey.

카미카사 하우스

ALTS 디자인(ALTS Design Office),카와무라 켄타(사진) 현대건축사 2023 (월간)Maru Vol.- No.237

ON PRESENTATIONS IN GRAMMARS OF THE DEFINITE AND INDEFINITE ARTICLES WITH AN ATTEMPT AT TEACHING THEM IN A NEW WAY TO THOSE WHOSE MOTHER TONGUE HAS NONE

Roland Alt 대구대학교 인문과학연구소 2008 人文科學硏究 Vol.31 No.-

관사(정관사와 부정관사)가 없는 언어를 모국어로 하는 사람은 관사가 있는 외국어를 배울 때, 관사 사용과 관련하여 많은 어려움을 겪고 있다. 이에, 본 연구에서는 관사가 없는 모국어를 사용하는 외국인이 프랑스어를 학습할 때 “왜 관사사용을 적절하게 할수 없는지”를 파악하고 이에 대한 효율적인 학습방안을 제시하기 위하여, 프랑스어 관사를 소개하는 문법책들을 분석한 후, 프랑스어에 관한 정관사와 부정관사(본 논문에서는 단수형에 국한하였다)의 사용 및 선택을 도와줄 수 있는 새로운 교수방법을 제안하였다.

Digital Transformation in the Restaurant Industry: Current Developments and Implications

Alt, Rainer Smart Tourism Research Center 2021 Journal of smart tourism Vol.1 No.1

Restaurants are an important area of the hospitality industry. This industry sector has not only experienced severe consequences of the recent lockdowns, but it has also seen the rise of digital technologies. As known from other industries, the digital transformation impacts products, processes and business models alike. Starting from the classical distinction of a restaurant's front- and back-of-the-house processes, this paper presents an overview on current developments in the restaurant industry and based on an analysis of current digital services, it derives some implications for future directions. Among the observations are that restaurants need to cover more touch points, provide more individualized offerings and strive for more automation as well as integration of their systems.

Etude de vocabulaire franc¸ais : Le "Voulez-vous + INF?" analyse se´mantique, dangers e´ventuels d'interpre´tation pour l'e´tranger semantic analysis, translation traps

Alt, Roland 대구대학교 인문과학 예술문화연구소 2003 人文科學硏究 Vol.25 No.-

The purpose of the present short study is to give to the foreign teacher of french, especially to a non-occidental reader, an overall view of the different possible values of the french expression (or structure) "Voulez-vous + INF?". Though the semi-auxiliary verb "vouloir", in regard of its main role in conversation, can be found in even the smallest bilingual french dictionary, the different values of this verb are not found in extenso in many mid-size dictionnary, and even in bigger ones. In these last ones which give usually more accurate information, all different values are not always be found in appropiate distinct paragraphs, in the "vouloir" verb entry. As an example Voulez-vous + INF is sometimes treated only as an another form or "Veuillez + INF, though this last form cannot generally be used as an equivalent of the former. In particular, must be remembered the fact that "Voulez-vous + INF?", though being grammatically a question, may have the value of a polite and/or formal command, and under its grammatical polite disguise, may even be cold and unsympathetic. When it corresponds to such disguised command, one have to understand that there is anyway a fondamental contradiction in this expression which is (grammatically) asking a question and at the same time (semantically) could be issuing a command to the very same person. This may bring difficulties of interpretation for the foreign student not yet clearly award of this fact. In addition we analyse why this unwareness may stay with a semi-beginner in French Language, longer than one may think in the first place.

Quelques aspects typographiques et orthographiques de la langue francaise de 1783 a travers l'etude d'une petite piece moraliste (1)

Alt, M. Roland 대구대학교 인문과학연구소 1992 人文科學硏究 Vol.10 No.-

"Some aspects of the typography and the orthography of the French Language of 1783 through the study of a small moralistic play" The aim of this paper is not so much to show that the French Language was not in 1783 much different from the French Language of to-day, which is quite a trivial observation, than to give the reader a real practical view of this fact. It is why we have thought it to be of the most importance to give here, with our remarks, and comments, not a transcription, but a copy of the original text printed in 1783, which allows the reader to feel at once some of the differences with the modern language, and first, some aspects of its typography. We begin indeed with a particularity of the typography, the different writings of the "s" minuscule, written with two different forms according to its position, and continue with some aspects of words orthography(accents, hyphen, diaresis), and grammatical orthography(adjectives, present participles, writing of the diphtongue "oi" instead of the modern "ai" in some grammatical endings) Also we have tried to give a mathematical assessment (percentages), of how much, in each case of difference, the text of 1783 is different from the modern language, which led us to give some statistical lists of occurences, and think of the best way to calculate the percentages. (Note : because of its length and, for printing management reasons, this paper is divided in two parts, the second being printed by the Institute of Foreign Language Studies of the same University. we ask the reader to refer in this second part to the photographical reproduction of the original text of 1783 studied here).