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폐 장외 증상을 동반한 크론병의 성공적인 아달리무맙 치료 증례
신동열 ( Dongyeol Shin ),박병규 ( Byung Kyu Park ),서정훈 ( Jeonghun Seo ),원선영 ( Sun Young Won ),이미경 ( Mi Kyoung Lee ),홍용국 ( Yong Kook Hong ),조용석 ( Yong Suk Cho ) 대한소화기학회 2018 대한소화기학회지 Vol.72 No.3
Pulmonary extraintestinal manifestation is rare in Crohn’s disease and has been reported in only a few cases. Despite the presence of pulmonary abnormalities in a significant proportion of patients with inflammatory bowel disease, there are only few case reports, due to complicated diagnosis and low recognition by clinicians. Currently, treatment guidelines for pulmonary Crohn's disease have not been established. There are some case reports of pulmonary Crohn’s disease that achieved remission after infliximab treatment. Clinical and radiological remission of pulmonary extraintestinal involvement in Crohn's disease after adalimumab therapy has not been reported yet. Here, we report one case of lung involvement of Crohn’s disease, which shows radiological and clinical remission after adalimumab treatment. (Korean J Gastroenterol 2018;72:141-145)
정재헌 ( Jae Heon Jeong ),신상윤 ( Sang Yun Shin ),손명균 ( Myoung Kyun Son ),이영주 ( Young Joo Lee ),김세현 ( Se Hyun Kim ),기정혜 ( Jeong Hae Kie ),최윤정 ( Yoon Jung Choi ),홍용국 ( Yong Kook Hong ),한창훈 ( Chang Hoon Hahn 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.2
악성 흉수의 원인은 폐암, 유방암, 및 악성 림프종, 백혈병이 그 대부분을 차지하며 내분비 종양에 의한 악성 흉수는 매우 드물며 특히 유두상 갑상선 암에 의한 흉수는 거의 없다. 저자들은 유두상 갑상선 암이 폐 전이를 거치지 않고 유방 전이를 거쳐 흉막 전이 일으킨 것으로 보이는 1예를 경험하였기에 보고하는 바이다. 아울러 원인이 명확하지 않은 악성 흉수의 원인 감별에 유두상 갑상선 암도 고려 대상으로 할 필요가 있다고 생각한다. Lung cancer, breast cancer and lymphoma are the common oncologic causes of malignant pleural effusion, comprising more than the half of the causes. However, an endocrinologic carcinoma associated malignant effusion is very rare. Recently, we encountered a case of papillary thyroid carcinoma causing malignant effusion. An 83-year-old female patient presented with dyspnea due to massive pleural effusion in her left side. The pleural biopsy, pleural fluid cytology and breast needle aspiration biopsy results were consistent with a metastatic papillary thyroid carcinoma. Thyroid ultrasonography showed two thyroid masses, but the patient refused a thyroid biopsy. This case highlights the need for considering the possibility of papillary thyroid carcinoma when the cause of malignant pleural effusion cannot be found because one of the rare clinical manifestations of a papillary thyroid carcinoma can be dyspnea due to malignant effusion. (Tuberc Respir Dis 2007; 63: 188-193)