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- 저자 : 노은지 ( Eun Ji Noh ) (검색결과 4 건)
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최수지 ( Su-ji Choi ),최윤석 ( Yunseok Choi ),이연선 ( Yeon Sun Lee ),노은지 ( Eun-ji Noh ),김동일 ( Dong-il Kim ) 경락경혈학회 2021 Korean Journal of Acupuncture Vol.38 No.2
Objectives : The purpose of this study is to review the acupuncture treatment for cold hypersensitivity of hands and feet. Methods : We searched articles in 7 search engines with keywords related to ‘Cold hypersensitivity of hands and feet’ and ‘Raynaud disease’ in March 2021. Clinical studies that used acupuncture for cold hypersensitivity of hands or feet were included. Animal studies and nonclinical data were excluded. Data on acupuncture treatment such as methods, site, duration, frequency, and period were analyzed. Also, network analysis between acupoints was conducted. Results : Of 41 selected articles, there were 32 case reports, 7 randomized controlled trials, and 2 uncontrolled clinical studies. Studies were conducted using manual acupuncture, electroacupuncture, warm needling, pharmacopuncture, fire needling, and auricular acupuncture. Most studies used more than one acupoint (n=40), and there were 111 acupoints selected for acupuncture treatment for cold hypersensitivity of hands and feet. The most commonly used acupoint was LI11 (n=27). In terms of the correlation of acupoints, LI11 had the highest value of degree centrality at 0.6989. The mean treatment time, number of treatments, and duration were 26.8±8.87 minutes, 15.51±15.75 times, and 77.69±132.80 days. Conclusions : The results of this study could be useful in establishing the evidence for performing standardized acupuncture treatment for cold hypersensitivity of hands and feet.
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조기분만진통 임부와 만삭 전 조기양막파열 임부의 정맥혈장내 산화 스트레스 지표
김윤하 ( Yoon Ha Kim ),노은지 ( Eun Ji Noh ),백주아 ( Ju A Back ),김종운 ( Jong Woon Kim ),송태복 ( Tae Bok Song ) 대한주산의학회 2015 Perinatology Vol.26 No.4
목적: 조기분만진통 및 만삭 전 조기양막파열 임부의 정맥혈장내 산화능과 항산화능의 차이를 비교하고 산화 스트레스가 조기양막파열의 병태생리에 어떤 역할을 하는가를 규명하고자 하였다.방법: 75명의 임부를 대상으로 정맥혈을 채취하고 원심분리 후 혈장을 얻었다. (1) A군, 정상 임부 24명, (2) B군, 조기분만진통 임부 25명, (3) C군, 만삭 전 조기양막파열 임부 26명. thiobarbituric acid 반응을 이용하여 지질과산화물 농도를 측정하였고, 2,4-dinitrophenylhydrazine 방법을 이용하여 단백질의 carbonyl 기 함량을 측정하였으며, oxygen radical absorbance capacity assay (ORAC)로 총 항산화능을 측정하였다. Mann-Whitney U test, Kruskal Wallis test를 이용하여 분석하였다. 결과: B군과 C군의 정맥혈장내 지질과산화 치는 A군에 비해 의미있게 높았으며(B군: 4.59±0.30, C군: 5.40±0.22 vs. A군: 3.90±0.26 nmol/mg protein, P<0.05), C군의 정맥혈장내 지질과산화 치는 B군에 비해 의미있게 높았다. C군의 정맥혈장내 carbonyl기 함량은 A군에 비해 의미있게 높았으며(C군: 5.68±0.42 vs. A군: 5.43±0.41 nmol/mg protein, P<0.05), A군과 B군간의 carbonyl기 함량에는 차이가 없었다. 항산화능에 있어서는 B군과 C군이 A군에 비해 의미있게 낮았으며(B군: 117.91±0.48, C군: 111.68±1.23 vs. A군: 119.14±1.12 mM/mL, P<0.05), C군이 B군에 비해 의미있게 낮았다(P<0.05). 결론: 만삭 전 조기양막파열시 조기분만진통에 비해 정맥혈장에서 산화적 변화가 증가되어 있었으며 항산화능은 감소되어 있었다. 이는 조기양막파열시 산화적 스트레스가 증가되어 있을 가능성을 시사한다. Purpose: This study was performed to investigate the oxidation and antioxidation capacity in the maternalvenous plasma of preterm labor with intact membranes, and premature rupture of membranes (PPROM), andalso to evaluate their roles in the pathophysiology of PPROM. Methods: Seventy five women in the following categories had venous blood retrieved: (1) Group A, normal pregnancy (n=24). (2) Group B, preterm labor with intact membranes (n=25). (3) Group C, preterm premature rupture of membranes (n=26). Malondialdehyde (MDA) levels as a marker of lipid peroxidation by thiobarbituric acid reaction, protein carbonyl content by 2,4-dinitrophenylhydrazine reaction, and total antioxidant capacity by oxygen radical absorbance capacity assay (ORAC) were measured. Mann-Whitney U test, Kruskal-Wallis test were used for statistical analysis. Results: Lipid peroxide levels in the venous plasma of group B and C were significantly higher than those of group A (group B: 4.59±0.30, group C: 5.40±0.22 vs. group A: 3.90±0.26 nmol/mg protein, P<0.05). Lipid peroxide levels in the venous plasma of group C were significantly higher than those of group B (P<0.05). Protein carbonyl levels in the venous plasma of group C were significantly higher than those of group A (group C: 5.68±0.42 vs. group A: 5.43±0.41 nmol/mg protein, P<0.05). There was no significant difference of protein carbonyl levels in the venous plasma between group A and B. ORAC levels in the venous plasma of group B and C were significantly lower than those of group A (group B: 117.90±0.48, group C: 111.68±1.23 vs. group A: 119.14±1.12 mM/mL, P<0.05). ORAC levels in the venous plasma of group C were significantly lower than those of group B (P<0.05). Conclusion: In the blood of the women with preterm premature rupture of membranes, the lipid peroxidation was increased and the antioxidant capacity was decreased compared to women with normal pregnancy and preterm labor with intact membranes. These results suggest that oxidative stress was increased in preterm premature rupture of membranes.
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산후풍의 진단적 정의 확립을 위한 전문가 델파이 조사 연구
오수경 ( Su-Kyoung Oh ),노은지 ( Eun-ji Noh ),최수지 ( Su-ji Choi ),김동일 ( Dong-il Kim ) 대한한방부인과학회 2021 大韓韓方婦人科學會誌 Vol.34 No.2
Objectives: The aim of this study was to establish a clear diagnostic definition of Sanhupung using the Delphi method. Methods: This study used the Delphi technique. A panel consisting of 21 experts of Korean medicine, particularly in of gynecologic medicine, participated in the Delphi examination that included answering the 4th round survey. The Delphi examination was carried out through evaluating and correcting the questionnaire by e-mail. Results: Through the Delphi survey, we have reached on an agreement regarding the basic concepts, time, cause, essential symptoms, and accessory symptoms of Sanhupung. They are as follows: 1) Sanhupung is a culture bound syndrome reflecting Korea's cultural specificity. 2) Sanhupung can be diagnosed even after the miscarriage. 3) For the diagnosis of Sanhupung, the main cause of symptoms should not be classified as other disease. 4) Sanhupung can be diagnosed based on essential symptoms and accessory symptoms. 5) Essential symptoms include local symptoms such as joint pain at specific areas, partial sensory impairment and general symptoms including pain of all the joints, whole body sensory impairment, increased sweating, feeling of wind coming into the body, worsened symptoms with the cold, intolerance to cold, and pain of all the muscles. Conclusions: The basic concepts and diagnostic definition of Sanhupung were suggested based on the Delphi survey among experts in the field. Further research is necessary to improve reliability and validity of diagnostic definition of Sanhupung in clinical trials.
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