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Liposarcoma involving the cheek : A case report and review of the literatures
양성익(Sung Ik Yang),이의웅(Eui Wung Lee),김진(Jin Kim),기화영(Wha Young Key) 대한구강악안면외과학회 1984 대한구강악안면외과학회지 Vol.10 No.1
Liposarcoma는 주로 근간 간엽조직으로 부터 기원되며, 남성에게서 약간 더 호발하고 중년 이후의 연령층에서 많이 발생된다. 하지와 복막후강에 가장 호발하며 두경부를 침범하는 경우는 드물고, 특히 구강주위조직을 침범하는 경우는 문헌조사에서 12예만을 발견할 수 있었다. 치료는 광범위한 외과적 절제 및 방사선 치료가 효과적으로 알려져 있다. 본 증례는 안면 좌측 협부의 종창을 주소로 내원한 22세의 여성으로, 전산화 단층사진을 포함한 방사선 사진검사및 조직 생검 결과, round-cell liposarcoma로 진단되어 광범위한 외과적 절제와 술후 악 6주간에 걸쳐 6200 rads의 방사선을 조사하여 치료하였으며 술후 약 5개월이 경과한 현재까지 재발의 증거는 보이지 않고 있다.
양성익(Sung Ik Yang),윤중호(Jung Ho Yoon),이정구(Jung Gu Lee) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.1
The gingival fibromatosis is a peculiar condition of gingival tumor which is characterized by an abnormal increase in the connective tissue elements of the gingival corium. Other names for this condition are elephantiasis gingivae, idiopathic fibrous hyperplasia of gingiva, congenital macrogingivae, gingivoma, hereditary hypertrophy of gum, gigantism of the gingiva, etc. The cause of the overgrowth of gingival tissue is not known, although it is probably genetic. A typical case of Gingival Fibromatosis presents large masses of firm, dense resilient, fibrous tissue that covers the alveolar ridge and varying portions of the crowns of teeth. The hyperplastic tissue is essentially normal in color and stippling, is insensitive and does not bleed easily. The hyperplasia may be noted at an early age and in a few cases even at birth. Teeth does not erupt normally because of the dense fibrous tissues. The patient s complaint is usually that of concern with the cosmetic appearance of the lesions or with interference with mouth functions. Surgical removal of the excess fibrous tissues is the only treatment of value. Recurrence may follow. We experienced a case of Gingival Fibromatosis in 1 10/12 year old female. Heredity was not combined and other abnormalities were not noted. Because of markedly enlarged gingiva on entire maxilla and mandible, no teeth were visible. We could obtain the good results in esthetics and functions by surgical excision of the hyperplastic gingival tissue.
CO₂Laser가 백서의 4-nitroquinoline 1-oxide(4NQO) 유도 구개암에 미치는 영향에 관한 실험적 연구
이의웅(Eui Wung Lee),양성익(Sung Ik Yang) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.2
The carbon dioxide laser has become more available widely in recent years and is now employed in many branches of surgery. It is important to understand the biological effects of CO₂ laser on normal oral mucosa and tumor tissues so that the likely response in patients can be predicted. However, little information is available on the biological effects of CO₂ laser in removing the tumor tissues. The present study was undertaken to investigate the effects of carbon dioxide laser on 4-nitroquinoline 1-oxide (4NQO) induced palatal carcinoma of the albino rats. 113 albino rats, Sprague Dawley strain, 6 week old, were used in this experimental study, divided into control group (15) and experimental group (30) in the first experiment (experimental carcinogenesis), then, normal group (33) and cancer group (35) in the second experiment (Laser irradiation). The first experiment was carried out to produce induced palatal carcinoma by the application of 0.5% 4NQO in propane 1,2-diol on palatal mucosa of the albino rats three times weekly for 30 weeks. The animals of experimental group were sacrificed every other week serially after the application of carcinogen. In the second experiment, CO₂ laser and blade wounds were created on normal palatal mucosa while laser wound on the tumor tissues. All animals were sacrificed serially immediately, 2, 4, 7, 14, 21, 28th day after each wound creation. The palatal mucosa was excised involving the laser or blade wounds. Tissue was examined grossly, light-microscopically and electron-microscopically. The obtained results were as follows. 1. In the experimental carcinogenesis for 4NQO induced palatal carcinoma, mild acanthosis only in 2 to 8th week, marked acanthosis with early acantholysis and epithelial dysplasia in 10 to 22th week and well differentiated squamous cell carcinoma in 24 to 30th week were observed lieht-microscopically. 2. In electron microscopic observation, we observed decrease of desmosomes and widening of intercelluar space in 6 to 10th week of carcinogenesis. Vacuolar degeneration and decrease of tonofilaments in cytoplasm were also seen in 10 to 20th week progressively. Lately, destruction of desmosome, widening of intercellular space, vacuolar degeneration and swelling of mitochondria in cytoplasm, cytoplasmic process extension with absence of basal lamina, irregular patterns of nucleus and cell features, prominent nucleoli were observed in 24 to 30th week of squamous cell carcinoma. 3. In light microscopic observation of the blade wounds in normal palatal mucosa, necrosis, inflammation and granulation tissue formation were seen until 7th day after wound creation but fibrosis and normal connective tissue formation were observed after 1st week, while in the laser wound, more severe necrosis, inflammation and granulation tissue formation were seen continuously until 3rd week, but fibrosis was seen on 3rd week and similar healing findings compared to blade wound were noted on 4th week. Fibrin thrombi formation was also observed variably within blood vessels. 4. In the laser wound of palatal carcinoma, its healing process was similar to that in normal palatal mucosa with extensive necrosis and fibrin thrombi within blood vessels, but the ultrastructural changes of tumor cell were not observed. Specific morphologic changes of the laser wound were extensive tissue necrosis and fibrin thrombi formation within blood vessels of connective tissue mainly, thus delayed healing was prominent in the early stage, but there were no significant differences between laser and blade wound in the later healing process. It was considered that direct dissemination of the tumor cell was probably inhibited due to vascular occlusion by intravascular thromboses during CO₂ laser surgery for malignant tumor
이충국(Choong Kook Lee),양성익(Sung Ik Yang),이용환(Yong Hwan Lee),이의홍(Eui Hong Lee),심현구(Hyun Goo Shim),차인호(In Ho Cha) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.1
In many cases, orthognathic surgical cases require multiple osteotomies in the maxilla and mandible to achieve the most desirable results. We have treated 7 patients with the dentofacial deformities by simultaneous repositioning of the maxilla and mandible. The results are as follows: 1. The mean duration of the surgical procedure was 9.56 hours. 2. The mean length of hospitalization was 8.86 days. 3. All patients required blood transfusions. They received a mean of 3.86 pints. 4. No patients experienced significant airway embarrasment requring emergency procedures.
증예보고 : Odontogenic Keratocyst 문헌고찰 및 증례보고
최병호(Byung Ho Choi),양성익(Sung Ik Yang) 대한악안면성형재건외과학회 1984 Maxillofacial Plastic Reconstructive Surgery Vol.6 No.1
The odontogenic keratocyst have high recurrence rate, and this lesion must be differentiated from nonkeratinizing cyst. We present a case of odontogenic keratocyst, and the literatures on odontogenic keratocyst are reviewed; the origin, microscopic characteristics, radiographic findings, clinical features, recurrence, and treatment of the lesion are discussed. The results are as follows; 1. This is a case of odontogenic keratocyst occurred on the impacted maxillary 2nd and 3rd molars area. 2. The odontogenic keratocyst have a histological characteristics for high recurrence rate. 3. It is necessary to make prebiopsy diagnosis before enucleation of cyst. The only definitive aid to prebiopsy diagnosis of a keratocyst is aspiration. 4. Patients should be followed postoperatively.
이충국(Choong Kook Lee),양성익(Sung Ik Yang),심현구(Hyun Goo Shim) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.1
This is a report of 5 odontogenic cysts treated by marsupialization and delayed enucleation or marsupialization only. The results were as follows; 1. The marsupialization and delayed enucleation technique allows rapid bone regeneration and eruption of the impacted canine in case 1. 2. Good results were obtained functionally and esthetically in all cases. 3. Follow up studies reveal no complication and recurrence.