Brenner Tumor의 1례

홍창수(CS Hong),황순경(SK Whang),이정기(JG Rhee),정구명(KM Chung) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.4

Since Brenner`s original description in 1907, much information on Brenner tumor of the ovary has been recorded such as a grooss and microscopic pathology. But three aspects of this tumor re,mains unsettled, the histogenesis, the possibility of estrogen production and their potential for malignancy. We reviewed a literatues on the Brenner tumor with a case of postmenopausal patient.

임산부와 태아갑상선 기능의 관계

홍창수(CS Hong),이헌영(HY Lee) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.2

저자는 태아와 모체의 갑상선 기능을 규명하기 위해 임신 17주부터 40주까지의 태아와 모체 각각 86예, 발육지연아와 이들의 모체 각각 12예, 산후 8일의 신생아 8예에서 T3 와 T4치를 측정하고 유리 thyroxine지수 T7치를 산출하여 다음과 같은 결론을 얻었다. 1. 17주부터 40주까지 태아의 T3치는 임산부나 비임신부보다 전체적으로 높은 치를 나타내 고 임신주수가 증가함에 따라 감소되는 경향을 보였다. 태아의 T4치는 임신부보다 낮으나 비임신 정상범위였으며 임신주수의 증가에 따라 증가되 는 경향을 보였다. 태아의 T7치는 임산부보다 높고 임신 주수에 따라 증가되는 경향을 보였으나 전예가 비임 부 정상범위내에 머물고 있었다. 임신부 T3치는 태아보다 낮고 비임부 정상치 보다도 낮으며 T4치는 태아와 비임부 정상치 보다 높았으나 T7치는 전예가 정상범위여서 갑상선 기능상태를 잘 반영했다. 2. 발육지연아와 정상아 간의 T3, T4, T7치의 상호 유의차는 발견할 수 없었다. 3. 산후 3일의 신생아는 T3, T4, T7치 모두 증가되어 갑상선 기능 항진상을 보였다. Thyroid funcion was determined with 125I-triiodothyronine resin uptake (T3 value), serum total thyroxime (T4 value) and free thyroxine index (T7 value) in the sera of 86 pairs of the maternal and the cord blood of the fetus of gestational age ranging from 17 to 40 weeks 12 pairs intrauterine growth retared (IUGR) group, and 8 newborns 3days of age . The results. 1. T3, T4, T7 values in the fetus and the pregnant women were summarized as follows. (a) T3 values in the fetus were sighnificantly higher than in the pregnant women, decreasing progressively with gestational age. T3 values in the pregnant women were sighnificantly lower than those of the euthyroid non-pregnant women. (b) T4 values in the fetus were significantly lower than in the pregnant women increasing pregressively with the gestational age, T4 values in the pregnant women were higher than the euthyroid non-pregnant women. (c) T7 values in the fetus increased progressively with gestational age but remained in the euthyroid range. T7 values in the pregnant women were also in the normal range of the euthyroid adult. 2. No significant differences in T3, T4 and T7 values exist between the mother of the IUGR and the term newborns nor between their IUGR infants and the term newborns. 3. T3, T4 and T7 values in the newborns were significantly higher at 3 days of age than at birth.

Fetal distress 에 대한 glucose 치료효과

김기진(KJ Kim),홍창수(CS Hong),최명학(MH Choi),유명렬(MY Yoo) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.10

It has been reported earlier that a certain relation exists between the glycogen content of the fetal heart and survival of the fetus under anoxia. The effests of maternal glucose loading on fetal distress were studies in 40 cases of full term pregnancy. One group of 20 cases server as controls without infusion of glucose, and the other study group of 20 cases was given an infusion of 50ml of 50% glucose solution intravenously 1-2 hours before delivery. Following the infusion of glucose solution, changes of fetal heart rates, plasma glucose levels, CO2 and O2 contents in the cord blood and amniotic fluid pH were determined & compared with those of control group. The results were as follows; 1) The umvilical arterial glucose content at birth was lower than that of umbilical venous blood and both arteral & venous glucose levels of the study group were found to be higer than those of control group. 2) In the cases of glucose loaded fetus, fetal heart activity was improved and stabilized. In the bradycardia group fetal heart rate was increased through whole labor course, but in the tachyc- ardua group the rate was reduced to normal range. (The difference between the control group and study group was highly significant:P<0,001) 3) Fetall amniotic pH, was found to be lower in the control group than in those of glucose laded group both in normal & distress fetus. In the glucose loaded cases the pH was lower in fetal distress group than those of normal group. 4) O2 contents of the corb blood,doth arterial and venous, were slightly higher in the study group than in the control group. 5) CO2 contents od the cord blood, both arterial and venous, were lower in the study group than in the control group. Statistical difference of the umbilical venous blood between the two group was highly significant. It is concluded that the infusion of glucose to the mother during late labor period is beneficial for the fetus to overcome possible distress during the birth.

처녀막 폐쇄증의 1례

천현(C Hyun),홍창수(CS Hong),박찬동(CD Park),안덕보(DB Ahn) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.12

Abstract Imperforated hymen is a relatively rare congenital anomaly of femaly genital tract. We are presented a case of hematocolpora and hematometra associated with imperforated hymen at the age of 18.

병합임신 1예

이주석(JS Lee),홍창수(CS Hong),서우갑(UG Suh),진성대(SD Jin) 대한산부인과학회 1973 Obstetrics & Gynecology Science Vol.16 No.6

저자들은 우측 난관 임신을 중절후 병합임신으로 진단되어 자궁내 임신이 9개월 후까지 지속한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A case of combined pregnancy which was relatively rare condition, was presented with brief review of literatures. A 29 years old woman, para 3, whose last menstrual period had occurred 9 weeks ago, was admitted complaining of the low abdominal pain, nausea and vomitting. The right salpingectomy was performed under the diagnosis of ectopic pregnancy. The accumulated blood in the abdominal cavity was about 1,000cc, and the uterus was enlarged, early three months gestation size. The Gravindex showed no agglutination on postoperative 7th day. The histologic findings revealed right tubal pregnancy. The uterus enlarged progressively, so it was slight smaller than man`s fist size on postoperative 2 weeks. The height of fundus was 17cm, and fetal heart sound was detected on right low abdomen with cephalic presentation on 11 weeks after operation. Aboue five hundred cases of combined pregnancy were reported until 1961. It has been estimated that combined pregnancy occurs in every 30,000 gestations. It must coexist in a live state at the same time, resulting from one fertilization or two separate fertilizations within a relatively short period of time. It must be therefore assumed that all combined pregnancy are the result of the fertilization of two ova.

거대첨규`콘디롬`의 1례

최명학(MH Choi),홍창수(CS Hong),정구윤(KY Chung),유명렬(MY Yoo) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.8

For the condyloma accuminatum, much informations has been decumented by many reportors but the huge size of condyloma accuminatum which we are going to report is uncommon. We reviewed literatures on the condyloma accuminatum.

자궁내번증의 1례

최진주(JJ Choi),홍창수(CS Hong),이재현(JH Lee) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.2

Inversvon of uterus is a rare obstetrical complication. We present a case of cute puerperal inversion of the uterus with fatal outcome and add a brief review of the literature.

임신 혈장 CBG를 이용한 황체 홀몬의 Competitive Protein Binding Assay에 관한 연구

김승조(SJ Kim),전정일(CI Chun),홍창수(CS Hong) 대한산부인과학회 1973 Obstetrics & Gynecology Science Vol.16 No.3

In order to get available corticosteroid binding globuline (CBG or Transcortin) for the measurement of plasma progesterone, competitive binging analysis with standard progesterone after making tritiated corticosterone-CBG complex was done for the binding specificity and affinity. Preparation and isolation of CBG from the blood plasma of human pregnant women in the third trimester was accomplished with filtration by Whatman 50 and precipitation by neutral salt followed ultracentrifuge. The results was as follows. (1) The presence of CBG with high affinity and specificity for binding progesterone has established in human pregnant women. (2) Competitive binding reaction of progesterone with tritiated corticosterone-CBG complex was satisfactory for the standard curve in which obtained over the useful range of bound percent from 90%(0.5ng) to 30%(16.0ng). (3) Eventhough disc electrophoresis have suggested the presence of albumin and other protein in the stripped and precipitated plasma with neutral salt, the CBG was highly specific and strong affinity to bind with steroids.