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      • SCOPUSKCI등재

        非小細胞性肺癌의 放射線治療 成績

        김일한(Il Han Kim),한성환(Sung Whon Ha),박찬일(Charn Il Park),심영수(Young Soo Shim),김락경(Noe Kyeong Kim),김건열(Keun Youl Kim),한용철(Yong Chol Han) 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.2

        From 1979 to 1982, 80 patients with unresectable non-small-cell lung cancer without metastasis were treated with high-dose radiotherapy to the primary and to regional lymph nodes with or without supraclavicular lymphatics in the Department of Therapeutic Radiology, Seoul National University Hospital. Of these, 56 patients(70%) were completely evaluable and 59 patients(74%) had squamous cell carcinoma, 13% large cell undifferentiated carcinoma and 8% adenocarcinoma, 21 patients(26%) had StageⅡ and 59 patients(74%) had Stage Ⅲ. The complete and parial response rate in the high-dose(≈6,000 rad) radiotherapy was 70% with 19% complete response, 69 patients(86%) failed in the treatment, by the failure pattern, 64% had local failure alone, 35% had local failure and distant metastasis and 1% had distant metastasis alone. The failure rate in the thorax were 76% in squamous cell carcinoma, 40% in adenocarcinoma and 20% in large cell undifferentiated carcinoma. Preliminary result shows that actuarial survival at 1, 2 and 3 years were 56%, 26% and 20% in overall patients and 64%, 37% and 21% in StageⅡ and 54%, 21% and 18% in StageⅢ, respectively. Overall median survival was 14 months; 17 months in StageⅡ and 13 months in StageⅢ. 8 patients(10%) have lived a minimum of 2 years with no evidence of disease. There was no fatal complication confirmed to be induced by radiotherapy, so definitive high-dose radiotherapy was tolerated well without major problems and resulted in good local control and survival.

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