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랜덤 포리스트를 이용한 비제어 급성 출혈성 쇼크의 흰쥐에서의 생존 예측
최준열,김성권,구정모,김덕원,Choi, J.Y.,Kim, S.K.,Koo, J.M.,Kim, D.W. 대한의용생체공학회 2012 의공학회지 Vol.33 No.3
Hemorrhagic shock is a primary cause of deaths resulting from injury in the world. Although many studies have tried to diagnose accurately hemorrhagic shock in the early stage, such attempts were not successful due to compensatory mechanisms of humans. The objective of this study was to construct a survival prediction model of rats in acute hemorrhagic shock using a random forest (RF) model. Heart rate (HR), mean arterial pressure (MAP), respiration rate (RR), lactate concentration (LC), and peripheral perfusion (PP) measured in rats were used as input variables for the RF model and its performance was compared with that of a logistic regression (LR) model. Before constructing the models, we performed 5-fold cross validation for RF variable selection, and forward stepwise variable selection for the LR model to examine which variables were important for the models. For the LR model, sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (ROC-AUC) were 0.83, 0.95, 0.88, and 0.96, respectively. For the RF models, sensitivity, specificity, accuracy, and AUC were 0.97, 0.95, 0.96, and 0.99, respectively. In conclusion, the RF model was superior to the LR model for survival prediction in the rat model.
권민경,최재림,최준열,장경환,김성권,김덕원,Kwon, M.K.,Choi, J.L.,Choi, J.Y.,Jang, K.H.,Kim, S.K.,Kim, D.W. 대한의용생체공학회 2012 의공학회지 Vol.33 No.2
With rapid increasing usage of smart phones, social concerns have arisen about the possible effects of electromagnetic fields emitted from wideband code division multiple access(WCDMA) mobile phones on human health. The number of people with self-reported electromagnetic hypersensitivity(EHS) who complain of various subjective symptoms such as headache, insomnia etc. has also recently increased. However, it is unclear whether EHS results from physiological or other origins. In this double-blinded study, we investigated physiological changes such as heart rate, respiration rate, and heart rate variability with real and sham exposures for 15 EHS and 17 non-EHS persons using a module inside a dummy phone. Experiment was conducted using a WCDMA module with average power of 24 dBm at 1950 MHz with the specific absorption rate of 1.57 W/kg using a headphone for 32 min. As a conclusion, WCDMA RF exposure did not have any effects on the physiological variables in either group.