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1% Pimecrolimus (Elidel(R)) 크림 국소 도포 후 발생한 잠행 백선
최윤림 ( Yun Lim Choi ),김정아 ( Jung Ah Kim ),노낙경 ( Nark Kyoung Rho ),이동윤 ( Dong Youn Lee ),이주흥 ( Joo Heung Lee ),양준모 ( Jun Mo Yang ),이일수 ( Eil Soo Lee ),김원석 ( Won Serk Kim ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.6
Tacrolimus and pimecrolimus represent a new class of topical non-steroidal medication currently used in the treatment of a variety of inflammatory skin lesions. We report a case of a patient in whom topical pimecrolimus therapy resulted in tinea incognito. Mycologic examination, including a KOH smear and fungal culture, was positive for hyphae and colonies of trichophyton mentagrophytes. The lesion was treated with oral griseofulvin and topical clotrimazole. (Korean J Dermatol 2006;44(6):731~733)
경피 전달을 위한 palmitoyl-KTTKS의 최적처방
이규진(Kyu-jin Lee),최윤림(Yun-lim Choi),신영희(Young-hee Shin) 대한약학회 2017 약학회지 Vol.61 No.2
Palmitoyl KTTKS (Pal-KTTKS), a derivative of KTTKS has been known for better skin penetration to stimulate skin matrix replenishment through topical application. The main purpose of this study was to find the opitmal formulation of pal-KTTKS for transdermal delivery. In this study, three kind of formulaion - hydrophilic, hydrophobic and emulsion formualtion were examined. On in vitro retention study, pal-KTTKS was retained with higher amount in stratum corneum than viable layer. The higher retention rate of pal-KTTKS was observed in the emulsion formulation than others.
김정아 ( Jung Ah Kim ),박지호 ( Ji Ho Park ),김송 ( Song Kim ),최윤림 ( Yun Lim Choi ),이동윤 ( Dong Youn Lee ),이일수 ( Eil Soo Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.7
Fibroepithelioma is a rare subtype of basal cell carcinoma (BCC) with a distinct growth pattern. We report a case of a 68 year-old man who presented with a 1.7×1.0×0.5 cm sized pedunculated mass on his left axilla. Histopathologic examination revealed two distinct patterns at the same time; a large nodular mass with a peripheral palisading pattern and a small locus of strands in a fenestrated fashion. In higher magnification, there were long, thin, branching, and anastomosing epithelial strands embedded in a fibrous stroma. Small buds were seen projecting from the epithelial strands, with many of the strands showing connections to the surface epidermis. The tumor was totally excised, and the patient has shown no evidence of recurrence for 4 months. This case shows an example of atypical fibroepithelioma with two distinct histopathologic types. (Korean J Dermatol 2007;45(7):728∼731)