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A Case of Metastatic Renal Cell CarcinomaMimicking Granuloma Pyogenicum
진원우,정지민,정경은,박종욱,김명화 대한피부과학회 2008 Annals of Dermatology Vol.20 No.4
Renal cell carcinoma (RCC) is well known for its frequent metastasis and particularly to the lungs, liver, bones and brain, but metastasis to the skin is rare. We report here on a case of metastatic RCC in a 73-year-old man who presented with a 1.5 cm sized, moist, beefy-red and exophytic nodule on the scalp. The lesion had grown rapidly for 2 months and it clinically mimicked granuloma pyogenicum. A skin biopsy revealed a solid mass composed of clear cells with clear cytoplasm and oval hyperchromatic nuclei, and they were arranged in an alveolar pattern. As skin metastasis from renal cell carcinoma signals widespread systemic metastasis and a poor prognosis, clinicians should conduct a careful inspection of the skin of a patient with RCC and they should also have a high index of suspicion for finding a primary internal organ malignancy in the RCC patients who present with a skin lesion.
Neurocristic Cutaneous Hamartoma의 형태를 보인 진피멜라닌세포 증식증
진원우 ( Won Woo Jin ),정경은 ( Kyoung Eun Jung ),박종욱 ( Jong Wook Park ),김명화 ( Myung Hwa Kim ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9
The dermal melanocytoses include a variety of pigment lesions that are formed from the aberrant development of the neural crest-derived melanocytes as they migrate through the dermis during embryogenesis. Neurocristic cutaneous hamartomas is one type of the dermal melanocytoses, which contain dermal melanocytic, neurosustentacular and fibrogenic components and can undergo malignant transformation. We describe a case of dermal melanocytosis showing features of neurocristic cutaneous hamartoma. (Korean J Dermatol 2008;46(9):1245~1248)