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송인성(In Sung Song),김정룡(Chung Yong Kim),이효석(Hyo Suk Lee),김용일(Yong Il Kim),김웅(Woong Kim),권현철(Hyeon Cheol Gwon),정현채(Hyun Chai Chung),윤용범(Yong Bum Lee) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.2
Primary biliary cirrhosis is a rare disease in Asia. A few case have been reported in Japan and only one case has been reported in Korea so far. The authors have experienced a case of primary biliary cirrhosis with Sjogren's syndrome in 49 year-old female who has suffered from eyeball pain and dry mouth since 4 years ago, and generalized pruritus since 1 month ago. She was treated with D- penicillamine and ursodeoxycholic acid with biochemical improvement. We report the second case of primary biliary cirrhosis in Korea and it is the first case of primary biiiary cirrhosis with Sjogren's syndrome in this country.
윤석주(Suk Joo Youn),정원재(Won Jae Jung),최상운(Sang Woon Choi),정현채(Hyun Chai Chung),김해련(Hae Ryun Kim),이효석(Hyo Suk Lee),윤용범(Yong Bum Youn),송인성(In Sung Song),김정룡(Chung Yong Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.5
N/A Between Nov. 1985 to Mar. 1987, we have administered endoscopic injection sclerotherapy to 54 patients who had bled from esophageal varices by intravariceal method and obtained following results: 1) In 27 patients who had reached complete sclerosis of esophageal varices, it took 4.7±1.9 (mean+SD) sessions (range 1-11 sessions) for complete sclerosing to occur. And taking the drop-out rate into consideration, complete sclerosis might be obtained in about 72% of patients with upto 7 sessions of treatment. 2) The failure rate of sclerotherapy representing death due to uncontrollable variceal hemorrhage and resort to operative management due to poor sclerosing response was below 10%. 3) Among those who have reached complete sclerosis, 11 patients were followed up for 1-11 months and in five of them (45%) further episodes of variceal bleeding were observed all of which were related to re-appearance of varices. 4) To prevent rebleeding from esophageal varices, it is important to maintain complete obliteration of varices and we recommend follow-up after complete sclerosis at 3 months` interval at least for the first one year. 5) Fatal complications have occurred at a rate of 1% on terms of treatment sessions in 5.5% of patients but with proper medical management no mortality has resulted. In conclusion, the endoscopic sclerotherapy using flexible endoscope and intravariceal injection method seems to be highly safe and may be an effective way of managing the patients with variceal hemorrhage both in acute control and long term prevention of variceal bleeding and therefore shou1d be considered as first line therapy prior to resort to operative measures.