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Canine Pneumoconiosis Caused by Fiberglass
김두,정자룡,장욱,박정화,김종택,Kim, Doo,Cheong, Cha-Ryong,Jang, Wook,Park, Jeong-Hwa,Kim, Jong-Taek The Korean Society of Veterinary Clinics 1996 한국임상수의학회지 Vol.13 No.2
Fiberglass may be a pulmonary toxin and carcinogen because it imitates asbestos, as do other man-made mineral fibers. A 5-months-old Jind dog was accidentally exposed to fiberglass extensively for 3 months in a site of apartment construction. Canine acute clinical pneumoconiosis caused by fiberglass was diagnosed by history, ezamination of environment, physical examination, and chest x-ray check of patient. The main signs were anorexia, dyspnea, increased irregular opacities and air trapping in lung field of chest x-ray films. Because the fiverglass which is used for several purpose are dangerous for health of animal and human. fiberglass dust must be controlled to minimize the adverse effects of fiberglass in the environment.
Staphylococcus aureus의 재조합 fibronectin-binding protein의 생산
김두,정자룡,박희명,한홍율,kim, Doo,Cheong, Cha-ryong,Park, Hee-myong,Han, Hong-ryul 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.4
To produce the recombinant fibronectin-binding protein(FnBP) for development of subunit vaccine against Staphylococcus aureus. The fnbp gene was amplified from the chromosomal DNA of S aureus KNU 196 strain using the polymerase chain reaction, and cloned into pGEX-4T-2. Then, the recombinant FnBP fused with glutathione-S-transferase was produced in E coli, purified by affinity chromatography, and identified its antigenicity and immunogenicity by Western blot. The recombinant FnBP produced in this study is considered to have the same property of native FnBP purified from S aureus, and is expected to be useful as a candidate for S aureus subunit vaccine.