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      • KCI등재

        고위험 임신부에서 양수내 Estriol , Human Placental Lactogen 및 Cortisol값과 Contraction Stress Test 성적과의 상관관계

        이진우(JW Lee),김기원(KW Kim),장봉림(BR Jang),노영숙(YS Roh),전은의(EE Chun) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.10

        임신 제 34-41주의 정상임신 87명의 양수내 estriol, human placental lactogen 및 cortisol을 측정하여 임신말기의 각 호르몬의 정상값을 구하였고, 임신 제 36-42주이상의 고위험 임신 부 158명에서 양수를 채취하여 estriol, human placental lactogen 및 cortisol을 측정하였으며 contraction stress test를 시행하여 contraction stress test 양성군과 음성군의 양수내 호르몬 측정치를 비교하고 진통중 태아감시 결과와 비교한 각 호르몬과 CST의 일치도를 점상관계 수로 구하여 다음과 같은 결론을 얻었다. 1. 정상임신의 임신 제 34, 36, 38 및 40 주에 따른 estriol값은 각각 340.7±132.04, 425.3±136348, 636.5±196.95, 906.1±295.72 ng/ml로 임신이 진행됨에 따라 점차 상승하였고 human placental lactogen값은 각각 0.60±0.203, 0.74±0.320, 0.63±0.262 0.53±0.171 ug/ml로 임신 제 36주까지 상승하다 그후 점차 감소하였으며 cortisol의 값은 각각 10.1+-3.08, 10.4±3.57, 17.6±4.38, 26.5±7.00 ng/ml로 임신 38주후에 급격히 상승하였다. 2. 고위험 임신에 있어서 저 estriol측정치에서 contraction stress test 양성율이 유의하게 높았 으나 human placental lactogen cortisol은 호르몬 값에 따른 contraction stress test 양성율과 유의한 차이가 없었으며 contraction stress test 와 양수내 estriol의 진통중 태아감시 결과와 의 일치도는 양수내 human placental lactogen cortisol에 비하여 유의하게 높았다. 3. 고위험 임신에 있어서 contraction stress test 와 양수내 estriol 측정의 진통중 태아 감시 결과와의 일치도는 각각 0.55와 0.71이었으나 2가지를 동시에 관찰하였을때는 0.85로 높아졌 다. 이상의 결과로 보아 양수내 제 estriol 이 CST결과에 만발성 태아심음수 감소상을 보임을 관 찰하였고 고위험 임신의 생리적 검사인 contraction stress test 결과의 관리지침을 얻기위해 서 생화학적 검사인 양수내 estriol측정을 함께 시행함이 바람직하다고 결론을 얻었다. Contraction stress test (CST) and measurement of three kinds of hormones in amniotic fluid were performed on 158 cases of term high-risk pregnancy during the period of antepartum care, and in 151 cases of them, the pattern of fetal heart rate curves of intrapartum fetal monitoring were analysed. the results were as follows; 1. The concentration of estriol in amniotic fluid between the 34th and 41st week of gestation increased to a mean value between 340.7-906.1 ng/ml, hPL decreased to a mean value 0.74-0.53 ug/ml and cortisol rapidly increased to a mean value between 10.1-26.5 ng/ml 2. There was significantly difference in CST positive rate between normal and low levels of estriol in amniotic fluid from high-risk pregnancy. In contrast there were no significant difference in CST positive rate between normal and abnormal levels of hPL and cortisol in amniotic fluid, the coefficients of estriol and CST analysed with the results of intrapartum fetal monitring were sighnificantly higher than that of hPL and cortisol. 3. the coefficients of estriol and CST were 0.71 and 0.55. When the results of both estriol and CST were analysed with those of intrapartum fetal monitoring simultaneously the coefficient increase to be 0.85. It can be concluded that among the concentration of hormones in amniotic fluid, the level of estriol is mostly well correlated with the results of CST, and the level of estriol is a parameter to analyse the interpretation of the less dependable CST during the period of antenatal care.

      • KCI등재

        전위분만에 관한 임상통계학적 고찰

        김대훈(DH Kim),허필형(PH Hur),김기원(KW Kim),한구택(GT Han),전은의(EE Chun) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.6

        1. The incidence of the breech presentation was 4.29% (1:23.3) 2. The age distribution was mostly concentrated between the age of 26 and 30 (57.8%). The frequency of the breech presentation was 53.22% in the primipara. 3. As to the gestational weeks, the frequency was mostly concentrated in the primipara between 37 and 40 gestational weeks (30.21%) and the multipara between 37 and 40 gestational weeks (26.0%) respectively. 4. The frank breech incidence was 51.90% complete breech incidence was 25.52% incomplete breech incidence was 20.1% and the compound breech incidence was 2.37%. 5. The prematurity was most common etiological factor and the next frequent factor was multiple pregnancy. The other contributable factors were the CPD, the low birth weight, the growth retardation, the PROM, the placenta-membrane cause and the congenital anomalies respectively. 6. The cesarean section rate was 46.61% and the vaginal delivery rate was 52.39% 7. As to the prognosis of the infants estimated by Apgar score, the depression rate of the infants by vaginal delivery was 3.5 times higher than that of cesarean section delivery and 5 times higher if the fetal weight was over 2500 gm. 8. The corrected perinatal mortality rate was 19.8% in the breech delivery and it was 5.9% in the case of the cesarean section delivery and 5 times higher in the vaginal delivery than in cesarean section delivery. The overall perinatal mortality rate was 5.88% if the fetal weight was over 2500gm

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