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        알코올 의존 환자에서 진전섬망과 금단증상의 연관성

        임지섭(Ji-Seop Lim),김현정(Hyun-Jung Kim),김임규(Im-Kyu Kim),강은찬(Eun-Chan Kang),이상민(Sang-Min Lee),공보금(Bo-Geum Kong),강제욱(Je-Wook Kang),문정준(Jung-Joon Moon),전동욱(Dong-Wook Jeon),정도운(Do-Un Jung) 대한노인정신의학회 2014 노인정신의학 Vol.18 No.2

        Objective:This study was performed to analyze the clinical variables associated with occurrence of delirium tremens (DT) in inpatients with alcohol dependence initially admitted with diseases unrelated to alcohol. Methods:This study included 132 inpatients seeking treatment for medical problem with acute alcohol withdrawal. The cases were divided into two groups : with DT group (n=44), without DT group (n=88). We compared the epidemiologic data, alcohol withdrawal symptoms and serum analysis data between two groups. We used the logistic regression to predict risk factors for DT. Results:The DT group had more severe alcohol withdrawal symptoms, more amount of drinking alcohol, more number of drinking per month, higher blood urea nitrogen (BUN), creatinine, amylase, C-reactive protein and lower serum total protein than the without-DT group. According to the result of a logistic regression, occurrence of DT showed correlation with the following factors : sweating, hallucination, agitation, amount of alcohol consumption, number of drinking per month. Conclusion:Our study suggests development of DT was correlated with severe alcohol withdrawal symptoms, high BUN, creatinine and low total serum protein. Therefore, during assessment of alcohol dependent patients, clinicians should keep these parameters in mind in order to prevent DT.

      • KCI등재

        자살 임박 시기 알코올 사용과 자살 기도의 특성

        김임규(Im-Gyu Kim),임지섭(Ji-Seop Lim),공보금(Bo-Geum Kong),강제욱(Je-Wook Kang),문정준(Jung-Joon Moon),전동욱(Dong-Wook Jeon),김성진(Sung-Jin Kim),김현정(Hyun-Jung Kim),정도운(Do-Un Jung) 대한생물치료정신의학회 2016 생물치료정신의학 Vol.22 No.1

        Objective:The aim of this study was to analyze the clinical characteristics of individuals who used alcohol at the time of attempting suicide. Methods:We divided 143 individuals who attempted suicide by consuming drugs into two groups on the basis of their blood alcohol concentration level: drinker group(n=79) and non-drinker group(n=64). We compared epidemio¬logical characteristics and suicidal behavior between the groups by using the Suicidal Intent Scale(SIS) and the Risk Rescue Rating Scale(RRRS). In addition, we administered the Glasgow Coma Scale(GCS) and the Acute Physiology and Chronic Health Evaluation-II(APACHE-II) to evaluate the medical lethality of the individuals who attempted sui¬cide. We used Student’s t-test, Pearson’s correlation analysis, and multiple linear regression to analyze the data. Results:The drinker group scored lower on the SIS’s planning subscale than the non-drinker group did(p=0.022). The drinker group’s blood alcohol concentration levels were negatively correlated with the rescue potential of their suicidal attempt(p=0.031) and the APACHE-II score(p=0.003). Higher blood alcohol concentration levels predicted poorer medical outcomes measured by the APACHE-II(p=0.004). Conclusion:Our findings support the notion that alcohol use increases suicidal impulsivity, decreases rescue po¬tential, and worsens medical outcomes. Therefore, suicide prevention programs need to include education and counseling about the risks associated with alcohol use.

      • KCI등재

        조현병 환자에서 정신병리와 인지 기능과의 연관성

        김성진(Sung-Jin Kim),심주철(Joo-Cheol Shim),공보금(Bo-Geum Kong),강제욱(Je-Wook Kang),문정준(Jung-Joon Moon),임지섭(Ji-Seop Lim),김임규(Im-Gyu Kim),김연수(Yeon-Sue Kim),오민경(Min-Kyung Oh),정도운(Do-Un Jung) 대한생물치료정신의학회 2013 생물치료정신의학 Vol.19 No.2

        Objectives:Cognitive dysfunction is one of the major symptoms of schizophrenia, and has a diverse effect on the prognosis and course of schizophrenia. Several studies have been done about the correlation between cognitive dysfunction and clinical symptoms of schizophrenia, but the results of those studies were not clear. This study was performed to confirm the correlation between cognitive dysfunction and clinical symptoms of schizophrenia. Methods:We studied 117 patients with schizophrenia. We assessed clinical symptoms and the cognitive function of the patients, and analyzed the statistical correlation between clinical symptoms and the cognitive function. For clinical symptoms, Positive and Negative Syndrome Scale(PANSS), Clinical Global Impression-Severity(CGI-S) and Hamilton Depression Rating Scale(HDRS) were performed. For cognitive function, Digit Span Test, Visual Span Test, Stroop Color Word Test(SCWT), Continuous Performance Test(CPT), Wisconsin Card Sorting Test(WCST), and Digit Symbol Substitution Test(DSST) were performed. Results:There was significant correlation between CPT and clinical symptoms. The WCST revealed that Categories Achieved(CA) have significant correlation with disorganization symptoms among 5-factor model of PANSS (p<0.05). DSST revealed that the total score(p<0.01), negative syndrome(p<0.01), general psychopathology(p<0.01) among 3 kind major area classification of PANSS and disorganization symptoms of 5-factor model of PANSS(p<0.001) have significant correlation. Conclusion:This study revealed the correlation between the cognitive function and a part of clinical symptoms in patients with schizophrenia, as shown through the CPT, WCST and DSST.

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