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다발성 골전이를 동반한 진행된 원발성 반지세포 폐암종(Primary Signet Ring Cell Carcinoma of Lung) 1예
신도현 ( Do Hyun Shin ),김형일 ( Hyoung Il Kim ),임선교 ( Seon Kyo Lim ),이승원 ( Seung Won Lee ),정연무 ( Youn Mu Jung ),최영인 ( Young In Choi ),신승수 ( Seung Soo Sheen ),박주헌 ( Joo Hun Park ),오윤정 ( Yoon Jung Oh ),박광주 ( 대한결핵 및 호흡기학회 2004 Tuberculosis and Respiratory Diseases Vol.57 No.6
전수진 ( Su Jin Jeon ),이광재 ( Kwang Jae Lee ),이명희 ( Myung Hee Lee ),임선교 ( Seon Kyo Lim ),강창준 ( Chang Jun Kang ),김진홍 ( Jin Hong Kim ) 대한소화기학회 2010 대한소화기학회지 Vol.56 No.4
Background/Aims: The individual course of Crohn`s disease is diverse, and some patients may require bowel resection. The aims of this study were to determine the early surgery rate of Crohn`s disease and to identify risk factors associated with early surgery in Korea. Methods: Ninety six patients with Crohn`s disease (68 men; median age at the time of diagnosis: 25 years), who had been followed up more than a year, were retrospectively analyzed. Early surgery was defined as a bowel operation for Crohn`s disease or its complications occurring within 3 years from diagnosis. Early surgery rate and risk factors for early surgery were identified. Results: Fifteen patients (15.6%) underwent early surgery. The cumulative surgery rate was 8.6% after 6 months, 11.9% after 12 months, 14.1% after 18 months, and 16.7% after 24 to 36 months. Multivariate analysis revealed penetrating or stricturing behavior to be an independent risk factor for early surgery (p<0.001, Exp (B)=2.97 CI 1.39-6.37). Conclusions: The cumulative early surgery rate in Korean patients seems to be lower than Western patients. Penetrating or stricturing behavior is significantly associated with early surgery, requiring early aggressive medical treatments. (Korean J Gastroenterol 2010;56:236-241)