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Temporal Changes in the Local Expression of Central HormoneRegulating Factors in Rat Testis
유시온,윤한서,김혜수,박진수,이성호 한국발생생물학회 2024 발생과 생식 Vol.28 No.1
Present study aimed to investigate the temporal changes in expression of some reproductive hormones in testis, originally found in hypothalamus and pituitary. Rats were sacrificed on postnatal day 23 (PND23; immature), pubertal (PND53) and PND 81 (young adult). The testicular RNAs were extracted, and semi-quantitative PCRs for gonadotropin-releasing hormone (GnRH), kisspeptin 1 (KiSS1), pituitary adenylate cyclase-activating polypeptide (PACAP), LH subunits and LH receptor were performed. Transcript levels of GnRH and KiSS1 at PND23 were significantly higher than levels of PND53 and PND81 (p<0.001). PACAP mRNA level at PND23 was significantly lower than those of PND53 and PND81 (p<0.001). The mRNA levels of both testis type and pituitary type luteinizing hormone β subunit (tLHβ and pLHβ, respectively) at PND23 were significantly lower than levels of PND53 and PND81 (p<0.001). The mRNA level of glycoprotein hormone common alpha subunit (Cgα) at PND23 was significantly lower than those of PND53 and PND81 (p<0.001). Present study revealed the intratesticular expression of KiSS1 and GnRH showed a very similar trend while the expression of PACAP in the testis showed reversed pattern. The expressions of LHβ subunits (tLHβ and pLHβ) were very low during immature stage then increased significantly during puberty and early adulthood. Our attempt to study the local role(s) of intratesticular factors will be helpful to achieve precise understanding on the testis physiology and pathology.
마이크로프로세서 기반의 실내 주차정보 제공 시스템 설계 및 구현
유시온(Si-On Yoo),오형진(Hyoung-Jin Oh),오갑석(Kab-Suk Oh) 한국컴퓨터정보학회 2010 韓國컴퓨터情報學會論文誌 Vol.15 No.1
아파트단지, 대형 빌딩, 마트 또는 백화점에는 많은 차량을 수용할 수 있는 실내 주차장이 구비되어 있으나, 운전자는 혼잡한 주차장에서 빈 주차구역을 찾기 위해 상당한 시간을 낭비하고 있다. 본 연구에서는 운전자가 혼잡한 주차장에서 현황모니터를 통해 빈 주차공간을 찾기 위해 배회하는 시간을 줄이고, 주차된 차량의 위치를 찾기 쉽도록 SMS(Short Message Service)를제공하는마이크로프로세서기반의실내주차정보제공시스템을제안한다. 제안시스템은 차량 출입 검출용 RFID(Radio-Frequency IDentification) 시스템, 주차면의 차량유무 관련 정보처리 및 서버와의 통신 등의 기능을 갖춘 마이크로프로세서 시스템, 진출입 차량의 정보처리와 운전자에게 빈 주차공간 및 주차정보를 안내하는 서버 시스템으로 구성하였다. 수작업으로 제작한 8대 규모의 모형주차장에 제안 시스템을 구현하였으며, 주차 현황 모니터와 유료 문자메시지 서비스로 운전자에게 정보를 제공함으로써 실용성을 확인하였다. Apartment complex, buildings, markets and department stores have inner parking lots which can accept many cars but drivers waste lots of times to find the empty parking spaces in crowding parking lots. In this paper, we proposed the inner parking information support system based on microprocessor which can decrease roaming times to find vacant parking spot in confusing parking lots through notice monitor and provide SMS to make it easy to find parked place. Proposed system consist with RFID system for detecting access of cars, microprocessor system for processing data of checking existence of cars on parking spots and communicating with server, and server system which processes information of cars' in and out, guides empty parking spots and parked location to drivers. Suggested system is realized by handmade model parking lot size of 8 cars, and we confirmed practicality by providing information using parking notice monitor and single message service.
웃음요법이 방사선요법을 받는 유방암 여성의 우울, 불안, 스트레스에 미치는 효과
김소희(Kim So Hee),김연희(Kim Yean Hee),김화정(Kim Hwa Jung),이순행(Lee Soon-Haeng),유시온(Yu Si On) 대한종양간호학회 2009 Asian Oncology Nursing Vol.9 No.2
Purpose: The purpose of this study was to investigate the of laughter therapy on depression, anxiety, and stress among patients underwent radiotherapy. Methods: Participants in the study were comprised of 60 breast cancer outpatients who received radiotherapy. Thirty-one of the patients were assigned in the experimental group and the other 29 patients made up the control group. Laughter therapy was consisted of the delivery of information and active motion resulting in laughter. We provided laughter therapy 4 times for 2 weeks. Each session lasted 60 min. The experimental group received laughter therapy intervention as a group. An average attendance frequency per person was 2.7. To evaluate the effect of laughter therapy, the degrees of depression and anxiety were measured by Hospital Anxiety and Depression (HAD) and stress was measured by the Brief Encounter Psychosocial Instrument (BEPSI). Data analysis included a 2-test, t-test, and Fisher’s exact test using SPSS 12.0 and SAS 8.0. Results: There was significant decrease in the degrees of depression, anxiety, and stress in the experimental group compared to those in the control group (p<.01, p=.04, and p<.01, respectively). Conclusion: This study provides evidence that laughter therapy is an effective intervention in improving depression, anxiety, and stress in breast cancer patients.