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제2형 당뇨병환자에서 혈중 글루카곤 농도와 심혈관 질환 위험도의 관계
정우석,문재철,유소연,Jeong, Wooseok,Moon, Jaecheol,Yoo, Soyeon 제주대학교 의과학연구소 2020 The Journal of Medicine and Life Science Vol.17 No.2
Glucagon regulates glucose and fat metabolism as well as being involved in the production of ketone bodies. The new antidiabetic drug, a sodium-glucose co-transporter-2 inhibitor, increases glucagon, and reduces the risk of cardiovascular death and hospitalization due to heart failure. The presence of metabolic syndrome is an important risk factor for cardiovascular diseases(CVD) in type 2 diabetes(T2DM) patients. We, thus, investigated the association between glucagon levels and metabolic syndrome in T2DM patients. This cross-sectional study involved 317 T2DM patients. Fasting and postprandial (30 min after ingestion of a standard mixed meal) glucagon levels were measured. Metabolic syndrome was defined according to the criteria of the International Diabetes Federation. A multiple regression logistic analysis was employed for statistical evaluation. A total of 219 (69%) subjects had metabolic syndrome. The fasting and postprandial glucagon levels did not differ between the group with metabolic syndrome and the group without. Postprandial glucagon levels increased significantly with the increase in the number of metabolic syndrome components, but the fasting levels did not. However, a hierarchical logistic regression analysis revealed that the postprandial glucagon levels did not contribute significantly to metabolic syndrome even after adjusting for other covariates. Fasting and postprandial glucagon levels are not associated with metabolic syndrome in T2DM patients. However, further studies are needed to investigate the relationship between glucagon and cardiovascular risk in patients with T2DM.
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사용후핵연료 처리 및 관리에 대한 시민들의 인식조사와 재공론화를 위한 제언
권근탁(Geun Tak Gwon),김지은(Ji Eun Kim),유소연(Soyeon Yoo),전상현(Sahng Hyun Jun),안삼영(Samyoung Ahn) 한국환경교육학회 2018 環境 敎育 Vol.31 No.3
우리나라는 사용후핵연료를 원자력발전소내에 저장 중이며, 저장량도 약 60∼80%의 포화상태여서 사용후핵연료를 영구처분할 처분장 마련이 매우 시급하다. 2013년부터 20개월 동안이 문제를 다루고 위한 사용후핵연료 공론화위원회가 활동하였지만, 정작 이를 아는 국민들은 거의 없었다. 본 연구는 국민들의 사용후핵연료에 대한 인식정도를 파악하고, 사용후핵연료 공론화위원회의 활동에 대한 평가를 통해 재공론화를 위한 제언을 마련하고자 하였다. 이를 위해 원전소재지, 원전소재지가 아닌 소도시, 지방 및 수도권 대학생 등 모두 네 집단을 대상으로 대면 설문조사하였다. 연구결과, 약 38∼57%의 국민들만 사용후핵연료 용어를 알고 있었으며, 연령별로는 40대와 50대에서 높은 인지도를 보였다. 사용후핵연료의 처리방법에 대해 20∼37%만이 바르게 인지하였다. 사용후핵연료 공론화위원회에 대해 피설문자의 약 80% 이상이 존재 자체를 알지 못하였으며 공론화위원회의 활동에 대해 보통이다라는 답변이 대다수였고, 매우 못했다와 못했다를 합한 비율이 매우 잘했다와 잘했다를 합한 비율보다 높았다. 약 70%의 응답자가 사용후핵연료 처리의 재공론화가 필요하다고 응답하였고, 재공론화 시에 가장 중점적으로 다뤄야 할 사항으로 ‘국민들에게 충분한 정보 제공과 홍보’가 1순위로 선택되었다. 재공론화가 성공하기 위해서는 이해가능한 일상의 언어로 의사소통과 정보제공이 이루어져야 한다는 것과 이를 위한 학교 및 사회 환경교육이 강화될 것을 제언한다. Spent Nuclear Fuel (SNF) from nuclear power plant reactors in Korea is currently stored within nuclear power plants, but having reached 60-80% of the existing storage capacity, determining a disposal site for their ultimate and safe storage is an urgent issue. The Public Engagement Commission on SNF management (PECOS) was launched in 2013 and operated for a period of 20 months to investigate the issue and to draw up suggestions for a consent-based national plan for the management and regulation of SNF and for a safe decommissioning process. However, the outcome of the Commission is little known to the public. In this work, we analyzed the public awareness on SNF and public evaluation of PECOS’ performance. According to the results, about 38-57% of the respondents knew the word SNF. Respondents in their 40s and 50s were twice as likely to know SNF as respondents in their 20s and 30s. Over 80% of the respondents reported that they have not heard of PECOS and of those that have heard of the commission; their evaluation of the performance of PECOS was rated as below average. About 70% of the respondents indicated that a re-launching of PECOS is necessary and an issue of key priority in re-launching the commission, as indicated by the respondents, is to ensure sufficient and transparent provision of information and public awareness raising activities. In conclusion, the study recommends that a re-launching of the commission is necessary, and key elements in this process are, first, to ensure transparent and understandable communication with the public to build trust between all stakeholders and, second, to intensify the environmental education about nuclear power in school and society.
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